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An aroA mutant of Yersinia pestis is attenuated in guinea-pigs, but virulent in mice.
Oyston PC, Russell P, Williamson ED, Titball RW. Oyston PC, et al. Among authors: russell p. Microbiology (Reading). 1996 Jul;142 ( Pt 7):1847-53. doi: 10.1099/13500872-142-7-1847. Microbiology (Reading). 1996. PMID: 8757748
A mutant of Burkholderia pseudomallei, auxotrophic in the branched chain amino acid biosynthetic pathway, is attenuated and protective in a murine model of melioidosis.
Atkins T, Prior RG, Mack K, Russell P, Nelson M, Oyston PC, Dougan G, Titball RW. Atkins T, et al. Among authors: russell p. Infect Immun. 2002 Sep;70(9):5290-4. doi: 10.1128/iai.70.9.5290-5294.2002. Infect Immun. 2002. PMID: 12183585 Free PMC article.
A single dose sub-unit vaccine protects against pneumonic plague.
Williamson ED, Eley SM, Stagg AJ, Green M, Russell P, Titball RW. Williamson ED, et al. Among authors: russell p. Vaccine. 2000 Oct 15;19(4-5):566-71. doi: 10.1016/s0264-410x(00)00159-6. Vaccine. 2000. PMID: 11027822
In killed whole cell vaccinees, physiologically significant levels of IgG to F1 only were detectable and the levels of F1-specific IgG in serum and in broncho-alveolar washings were significantly lower (p<0.05) compared with sub-unit vaccinees. In sub-unit vaccinees, an …
In killed whole cell vaccinees, physiologically significant levels of IgG to F1 only were detectable and the levels of F1-specific IgG in se …
Efficacy of the latest fluoroquinolones against experimental Yersinia pestis.
Steward J, Lever MS, Russell P, Beedham RJ, Stagg AJ, Taylor RR, Brooks TJ. Steward J, et al. Among authors: russell p. Int J Antimicrob Agents. 2004 Dec;24(6):609-12. doi: 10.1016/j.ijantimicag.2004.06.011. Int J Antimicrob Agents. 2004. PMID: 15555886
Passive protection against Burkholderia pseudomallei infection in mice by monoclonal antibodies against capsular polysaccharide, lipopolysaccharide or proteins.
Jones SM, Ellis JF, Russell P, Griffin KF, Oyston PCF. Jones SM, et al. Among authors: russell p. J Med Microbiol. 2002 Dec;51(12):1055-1062. doi: 10.1099/0022-1317-51-12-1055. J Med Microbiol. 2002. PMID: 12466403
The SCID/Beige mouse as a model to investigate protection against Yersinia pestis.
Green M, Rogers D, Russell P, Stagg AJ, Bell DL, Eley SM, Titball RW, Williamson ED. Green M, et al. Among authors: russell p. FEMS Immunol Med Microbiol. 1999 Feb;23(2):107-13. doi: 10.1111/j.1574-695X.1999.tb01229.x. FEMS Immunol Med Microbiol. 1999. PMID: 10076907
Comparison of the immunological and protective responses elicited by microencapsulated formulations of the F1 antigen from Yersinia pestis.
Reddin KM, Easterbrook TJ, Eley SM, Russell P, Mobsby VA, Jones DH, Farrar GH, Williamson ED, Robinson A. Reddin KM, et al. Among authors: russell p. Vaccine. 1998 May;16(8):761-7. doi: 10.1016/s0264-410x(97)00305-8. Vaccine. 1998. PMID: 9627932
Antigen encapsulated in PLG microparticles induced high serum titres when injected i.p. in mice: mucosal IgA was also detected. ...
Antigen encapsulated in PLG microparticles induced high serum titres when injected i.p. in mice: mucosal IgA was also detected. ...
Efficacy of doxycycline and ciprofloxacin against experimental Yersinia pestis infection.
Russell P, Eley SM, Green M, Stagg AJ, Taylor RR, Nelson M, Beedham RJ, Bell DL, Rogers D, Whittington D, Titball RW. Russell P, et al. J Antimicrob Chemother. 1998 Feb;41(2):301-5. doi: 10.1093/jac/41.2.301. J Antimicrob Chemother. 1998. PMID: 9533478
A sub-unit vaccine elicits IgG in serum, spleen cell cultures and bronchial washings and protects immunized animals against pneumonic plague.
Williamson ED, Eley SM, Stagg AJ, Green M, Russell P, Titball RW. Williamson ED, et al. Among authors: russell p. Vaccine. 1997 Jul;15(10):1079-84. doi: 10.1016/s0264-410x(96)00303-9. Vaccine. 1997. PMID: 9269050
Levels of F1-specific IgG in serum, secreted from spleen cells and in BAL were significantly higher (P < 0.01) in sub-unit compared with killed whole cell vaccinees. ...

Levels of F1-specific IgG in serum, secreted from spleen cells and in BAL were significantly higher (P < 0.01) in sub-unit compare

A new improved sub-unit vaccine for plague: the basis of protection.
Williamson ED, Eley SM, Griffin KF, Green M, Russell P, Leary SE, Oyston PC, Easterbrook T, Reddin KM, Robinson A, et al. Williamson ED, et al. Among authors: russell p. FEMS Immunol Med Microbiol. 1995 Dec;12(3-4):223-30. doi: 10.1111/j.1574-695X.1995.tb00196.x. FEMS Immunol Med Microbiol. 1995. PMID: 8745007
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