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Notch is a direct negative regulator of the DNA-damage response.
Vermezovic J, Adamowicz M, Santarpia L, Rustighi A, Forcato M, Lucano C, Massimiliano L, Costanzo V, Bicciato S, Del Sal G, d'Adda di Fagagna F. Vermezovic J, et al. Among authors: rustighi a. Nat Struct Mol Biol. 2015 May;22(5):417-24. doi: 10.1038/nsmb.3013. Epub 2015 Apr 20. Nat Struct Mol Biol. 2015. PMID: 25895060 Free article.
HMGA1 inhibits the function of p53 family members in thyroid cancer cells.
Frasca F, Rustighi A, Malaguarnera R, Altamura S, Vigneri P, Del Sal G, Giancotti V, Pezzino V, Vigneri R, Manfioletti G. Frasca F, et al. Among authors: rustighi a. Cancer Res. 2006 Mar 15;66(6):2980-9. doi: 10.1158/0008-5472.CAN-05-2637. Cancer Res. 2006. PMID: 16540646 Free article.
Inhibition of the peptidyl-prolyl-isomerase Pin1 enhances the responses of acute myeloid leukemia cells to retinoic acid via stabilization of RARalpha and PML-RARalpha.
Gianni' M, Boldetti A, Guarnaccia V, Rambaldi A, Parrella E, Raska I Jr, Rochette-Egly C, Del Sal G, Rustighi A, Terao M, Garattini E. Gianni' M, et al. Among authors: rustighi a. Cancer Res. 2009 Feb 1;69(3):1016-26. doi: 10.1158/0008-5472.CAN-08-2603. Epub 2009 Jan 20. Cancer Res. 2009. PMID: 19155306
A Pin1/mutant p53 axis promotes aggressiveness in breast cancer.
Girardini JE, Napoli M, Piazza S, Rustighi A, Marotta C, Radaelli E, Capaci V, Jordan L, Quinlan P, Thompson A, Mano M, Rosato A, Crook T, Scanziani E, Means AR, Lozano G, Schneider C, Del Sal G. Girardini JE, et al. Among authors: rustighi a. Cancer Cell. 2011 Jul 12;20(1):79-91. doi: 10.1016/j.ccr.2011.06.004. Cancer Cell. 2011. PMID: 21741598 Free article.
Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast.
Rustighi A, Zannini A, Tiberi L, Sommaggio R, Piazza S, Sorrentino G, Nuzzo S, Tuscano A, Eterno V, Benvenuti F, Santarpia L, Aifantis I, Rosato A, Bicciato S, Zambelli A, Del Sal G. Rustighi A, et al. EMBO Mol Med. 2014 Jan;6(1):99-119. doi: 10.1002/emmm.201302909. Epub 2013 Dec 15. EMBO Mol Med. 2014. PMID: 24357640 Free PMC article.
43 results