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The unc-86 gene product couples cell lineage and cell identity in C. elegans.
Finney M, Ruvkun G. Finney M, et al. Among authors: ruvkun g. Cell. 1990 Nov 30;63(5):895-905. doi: 10.1016/0092-8674(90)90493-x. Cell. 1990. PMID: 2257628
Regulation of the mec-3 gene by the C.elegans homeoproteins UNC-86 and MEC-3.
Xue D, Finney M, Ruvkun G, Chalfie M. Xue D, et al. Among authors: ruvkun g. EMBO J. 1992 Dec;11(13):4969-79. EMBO J. 1992. PMID: 1361171 Free PMC article.
Dominant gain-of-function mutations that lead to misregulation of the C. elegans heterochronic gene lin-14, and the evolutionary implications of dominant mutations in pattern-formation genes.
Ruvkun G, Wightman B, Bürglin T, Arasu P. Ruvkun G, et al. Dev Suppl. 1991;1:47-54. Dev Suppl. 1991. PMID: 1742500
Negative regulatory sequences in the lin-14 3'-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development.
Wightman B, Bürglin TR, Gatto J, Arasu P, Ruvkun G. Wightman B, et al. Among authors: ruvkun g. Genes Dev. 1991 Oct;5(10):1813-24. doi: 10.1101/gad.5.10.1813. Genes Dev. 1991. PMID: 1916264
Temporal regulation of lin-14 by the antagonistic action of two other heterochronic genes, lin-4 and lin-28.
Arasu P, Wightman B, Ruvkun G. Arasu P, et al. Among authors: ruvkun g. Genes Dev. 1991 Oct;5(10):1825-33. doi: 10.1101/gad.5.10.1825. Genes Dev. 1991. PMID: 1916265
Regulation of transcription and cell identity by POU domain proteins.
Ruvkun G, Finney M. Ruvkun G, et al. Cell. 1991 Feb 8;64(3):475-8. doi: 10.1016/0092-8674(91)90227-p. Cell. 1991. PMID: 1991317 Review. No abstract available.
Molecular genetics of the Caenorhabditis elegans heterochronic gene lin-14.
Ruvkun G, Ambros V, Coulson A, Waterston R, Sulston J, Horvitz HR. Ruvkun G, et al. Genetics. 1989 Mar;121(3):501-16. Genetics. 1989. PMID: 2565854 Free PMC article.
Caenorhabditis elegans has scores of homoeobox-containing genes.
Bürglin TR, Finney M, Coulson A, Ruvkun G. Bürglin TR, et al. Among authors: ruvkun g. Nature. 1989 Sep 21;341(6239):239-43. doi: 10.1038/341239a0. Nature. 1989. PMID: 2571091
The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors.
Finney M, Ruvkun G, Horvitz HR. Finney M, et al. Among authors: ruvkun g. Cell. 1988 Dec 2;55(5):757-69. doi: 10.1016/0092-8674(88)90132-8. Cell. 1988. PMID: 2903797
The Caenorhabditis elegans heterochronic gene lin-14 encodes a nuclear protein that forms a temporal developmental switch.
Ruvkun G, Giusto J. Ruvkun G, et al. Nature. 1989 Mar 23;338(6213):313-9. doi: 10.1038/338313a0. Nature. 1989. PMID: 2922060
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