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Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor.
Paradis S, Ruvkun G. Paradis S, et al. Among authors: ruvkun g. Genes Dev. 1998 Aug 15;12(16):2488-98. doi: 10.1101/gad.12.16.2488. Genes Dev. 1998. PMID: 9716402 Free PMC article.
C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons.
Miller DM, Shen MM, Shamu CE, Bürglin TR, Ruvkun G, Dubois ML, Ghee M, Wilson L. Miller DM, et al. Among authors: ruvkun g. Nature. 1992 Feb 27;355(6363):841-5. doi: 10.1038/355841a0. Nature. 1992. PMID: 1347150
Negative regulatory sequences in the lin-14 3'-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development.
Wightman B, Bürglin TR, Gatto J, Arasu P, Ruvkun G. Wightman B, et al. Among authors: ruvkun g. Genes Dev. 1991 Oct;5(10):1813-24. doi: 10.1101/gad.5.10.1813. Genes Dev. 1991. PMID: 1916264
Temporal regulation of lin-14 by the antagonistic action of two other heterochronic genes, lin-4 and lin-28.
Arasu P, Wightman B, Ruvkun G. Arasu P, et al. Among authors: ruvkun g. Genes Dev. 1991 Oct;5(10):1825-33. doi: 10.1101/gad.5.10.1825. Genes Dev. 1991. PMID: 1916265
Regulation of transcription and cell identity by POU domain proteins.
Ruvkun G, Finney M. Ruvkun G, et al. Cell. 1991 Feb 8;64(3):475-8. doi: 10.1016/0092-8674(91)90227-p. Cell. 1991. PMID: 1991317 Review. No abstract available.
The unc-86 gene product couples cell lineage and cell identity in C. elegans.
Finney M, Ruvkun G. Finney M, et al. Among authors: ruvkun g. Cell. 1990 Nov 30;63(5):895-905. doi: 10.1016/0092-8674(90)90493-x. Cell. 1990. PMID: 2257628
Molecular genetics of the Caenorhabditis elegans heterochronic gene lin-14.
Ruvkun G, Ambros V, Coulson A, Waterston R, Sulston J, Horvitz HR. Ruvkun G, et al. Genetics. 1989 Mar;121(3):501-16. Genetics. 1989. PMID: 2565854 Free PMC article.
Caenorhabditis elegans has scores of homoeobox-containing genes.
Bürglin TR, Finney M, Coulson A, Ruvkun G. Bürglin TR, et al. Among authors: ruvkun g. Nature. 1989 Sep 21;341(6239):239-43. doi: 10.1038/341239a0. Nature. 1989. PMID: 2571091
The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors.
Finney M, Ruvkun G, Horvitz HR. Finney M, et al. Among authors: ruvkun g. Cell. 1988 Dec 2;55(5):757-69. doi: 10.1016/0092-8674(88)90132-8. Cell. 1988. PMID: 2903797
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