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Protein kinase CK2 inhibition as a pharmacological strategy.
Borgo C, Ruzzene M. Borgo C, et al. Among authors: ruzzene m. Adv Protein Chem Struct Biol. 2021;124:23-46. doi: 10.1016/bs.apcsb.2020.09.003. Epub 2021 Jan 9. Adv Protein Chem Struct Biol. 2021. PMID: 33632467 Review.
Protein kinase CK2 protects multiple myeloma cells from ER stress-induced apoptosis and from the cytotoxic effect of HSP90 inhibition through regulation of the unfolded protein response.
Manni S, Brancalion A, Tubi LQ, Colpo A, Pavan L, Cabrelle A, Ave E, Zaffino F, Di Maira G, Ruzzene M, Adami F, Zambello R, Pitari MR, Tassone P, Pinna LA, Gurrieri C, Semenzato G, Piazza F. Manni S, et al. Among authors: ruzzene m. Clin Cancer Res. 2012 Apr 1;18(7):1888-900. doi: 10.1158/1078-0432.CCR-11-1789. Epub 2012 Feb 20. Clin Cancer Res. 2012. PMID: 22351691
Therapeutic targeting of CK2 in acute and chronic leukemias.
Buontempo F, McCubrey JA, Orsini E, Ruzzene M, Cappellini A, Lonetti A, Evangelisti C, Chiarini F, Evangelisti C, Barata JT, Martelli AM. Buontempo F, et al. Among authors: ruzzene m. Leukemia. 2018 Jan;32(1):1-10. doi: 10.1038/leu.2017.301. Epub 2017 Sep 27. Leukemia. 2018. PMID: 28951560 Free PMC article. Review.
143 results