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Elongation factor-2 kinase and its newly discovered relatives.
Ryazanov AG. Ryazanov AG. FEBS Lett. 2002 Mar 6;514(1):26-9. doi: 10.1016/s0014-5793(02)02299-8. FEBS Lett. 2002. PMID: 11904175 Review.
eEF-2 kinase is a critical regulator of Warburg effect through controlling PP2A-A synthesis.
Cheng Y, Ren X, Yuan Y, Shan Y, Li L, Chen X, Zhang L, Takahashi Y, Yang JW, Han B, Liao J, Li Y, Harvey H, Ryazanov A, Robertson GP, Wan G, Liu D, Chen AF, Tao Y, Yang JM. Cheng Y, et al. Oncogene. 2016 Dec 8;35(49):6293-6308. doi: 10.1038/onc.2016.166. Epub 2016 May 16. Oncogene. 2016. PMID: 27181208
The alpha-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC.
Clark K, Middelbeek J, Dorovkov MV, Figdor CG, Ryazanov AG, Lasonder E, van Leeuwen FN. Clark K, et al. FEBS Lett. 2008 Sep 3;582(20):2993-7. doi: 10.1016/j.febslet.2008.07.043. Epub 2008 Aug 7. FEBS Lett. 2008. PMID: 18675813
Paradoxical Roles of Elongation Factor-2 Kinase in Stem Cell Survival.
Liao Y, Chu HP, Hu Z, Merkin JJ, Chen J, Liu Z, Degenhardt K, White E, Ryazanov AG. Liao Y, et al. Among authors: ryazanov ag. J Biol Chem. 2016 Sep 9;291(37):19545-57. doi: 10.1074/jbc.M116.724856. Epub 2016 Jul 27. J Biol Chem. 2016. PMID: 27466362 Free PMC article.
Pharmacological eEF2K activation promotes cell death and inhibits cancer progression.
De Gassart A, Demaria O, Panes R, Zaffalon L, Ryazanov AG, Gilliet M, Martinon F. De Gassart A, et al. Among authors: ryazanov ag. EMBO Rep. 2016 Oct;17(10):1471-1484. doi: 10.15252/embr.201642194. Epub 2016 Aug 29. EMBO Rep. 2016. PMID: 27572820 Free PMC article.
Phosphorylation of annexin I by TRPM7 channel-kinase.
Dorovkov MV, Ryazanov AG. Dorovkov MV, et al. J Biol Chem. 2004 Dec 3;279(49):50643-6. doi: 10.1074/jbc.C400441200. Epub 2004 Oct 12. J Biol Chem. 2004. PMID: 15485879
Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel.
Ryazanova LV, Dorovkov MV, Ansari A, Ryazanov AG. Ryazanova LV, et al. J Biol Chem. 2004 Jan 30;279(5):3708-16. doi: 10.1074/jbc.M308820200. Epub 2003 Oct 30. J Biol Chem. 2004. PMID: 14594813
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