Rybczynski PJ - Search Results

1

Glycosylated dihydrochalcones as potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitors.

Dudash J Jr, Zhang X, Zeck RE, Johnson SG, Cox GG, Conway BR, Rybczynski PJ, Demarest KT. Dudash J Jr, et al. Among authors: rybczynski pj. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5121-5. doi: 10.1016/j.bmcl.2004.07.082. Bioorg Med Chem Lett. 2004. PMID: 15380212

2

Synthesis and evaluation of nonpeptide substituted spirobenzazepines as potent vasopressin antagonists.

Xiang MA, Chen RH, Demarest KT, Gunnet J, Look R, Hageman W, Murray WV, Combs DW, Rybczynski PJ, Patel M. Xiang MA, et al. Among authors: rybczynski pj. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3143-6. doi: 10.1016/j.bmcl.2004.04.016. Bioorg Med Chem Lett. 2004. PMID: 15149662

3

Synthesis and evaluation of 3-anilino-quinoxalinones as glycogen phosphorylase inhibitors.

Dudash J Jr, Zhang Y, Moore JB, Look R, Liang Y, Beavers MP, Conway BR, Rybczynski PJ, Demarest KT. Dudash J Jr, et al. Among authors: rybczynski pj. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4790-3. doi: 10.1016/j.bmcl.2005.07.021. Bioorg Med Chem Lett. 2005. PMID: 16143521

4

Heteroaryl-O-glucosides as novel sodium glucose co-transporter 2 inhibitors. Part 1.

Zhang X, Urbanski M, Patel M, Zeck RE, Cox GG, Bian H, Conway BR, Pat Beavers M, Rybczynski PJ, Demarest KT. Zhang X, et al. Among authors: rybczynski pj. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5202-6. doi: 10.1016/j.bmcl.2005.08.067. Epub 2005 Sep 28. Bioorg Med Chem Lett. 2005. PMID: 16198559

5

Indole-glucosides as novel sodium glucose co-transporter 2 (SGLT2) inhibitors. Part 2.

Zhang X, Urbanski M, Patel M, Cox GG, Zeck RE, Bian H, Conway BR, Beavers MP, Rybczynski PJ, Demarest KT. Zhang X, et al. Among authors: rybczynski pj. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1696-701. doi: 10.1016/j.bmcl.2005.12.006. Epub 2005 Dec 27. Bioorg Med Chem Lett. 2006. PMID: 16380256

6

Design and synthesis of indane-ureido-thioisobutyric acids: A novel class of PPARalpha agonists.

Matthews JM, Chen X, Cryan E, Hlasta DJ, Rybczynski PJ, Strauss K, Tang Y, Xu JZ, Yang M, Zhou L, Demarest KT. Matthews JM, et al. Among authors: rybczynski pj. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6773-8. doi: 10.1016/j.bmcl.2007.10.041. Epub 2007 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 18029176

7

Benzoxazinones as PPARgamma agonists. part 1: SAR of three aromatic regions.

Rybczynski PJ, Zeck RE, Combs DW, Turchi I, Burris TP, Xu JZ, Yang M, Demarest KT. Rybczynski PJ, et al. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2359-62. doi: 10.1016/s0960-894x(03)00401-3. Bioorg Med Chem Lett. 2003. PMID: 12824034

8

2,5-disubstituted 3,4-dihydro-2H-benzo[b][1,4]thiazepines as potent and selective V2 arginine vasopressin receptor antagonists.

Urbanski MJ, Chen RH, Demarest KT, Gunnet J, Look R, Ericson E, Murray WV, Rybczynski PJ, Zhang X. Urbanski MJ, et al. Among authors: rybczynski pj. Bioorg Med Chem Lett. 2003 Nov 17;13(22):4031-4. doi: 10.1016/j.bmcl.2003.08.051. Bioorg Med Chem Lett. 2003. PMID: 14592501

9

Benzoxazinones as PPARgamma agonists. 2. SAR of the amide substituent and in vivo results in a type 2 diabetes model.

Rybczynski PJ, Zeck RE, Dudash J Jr, Combs DW, Burris TP, Yang M, Osborne MC, Chen X, Demarest KT. Rybczynski PJ, et al. J Med Chem. 2004 Jan 1;47(1):196-209. doi: 10.1021/jm0301888. J Med Chem. 2004. PMID: 14695833

10

Next-generation spirobenzazepines: identification of RWJ-676070 as a balanced vasopressin V1a/V2 receptor antagonist for human clinical studies.

Xiang MA, Rybczynski PJ, Patel M, Chen RH, McComsey DF, Zhang HC, Gunnet JW, Look R, Wang Y, Minor LK, Zhong HM, Villani FJ, Demarest KT, Damiano BP, Maryanoff BE. Xiang MA, et al. Among authors: rybczynski pj. Bioorg Med Chem Lett. 2007 Dec 1;17(23):6623-8. doi: 10.1016/j.bmcl.2007.09.059. Epub 2007 Sep 19. Bioorg Med Chem Lett. 2007. PMID: 17942308

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