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A multimodal approach to identify clinically relevant biomarkers to comprehensively monitor disease progression in a mouse model of pediatric neurodegenerative disease.
Johnson TB, Brudvig JJ, Lehtimäki KK, Cain JT, White KA, Bragge T, Rytkönen J, Huhtala T, Timm D, Vihma M, Puoliväli JT, Poutiainen P, Nurmi A, Weimer JM. Johnson TB, et al. Among authors: rytkonen j. Prog Neurobiol. 2020 Jun;189:101789. doi: 10.1016/j.pneurobio.2020.101789. Epub 2020 Mar 18. Prog Neurobiol. 2020. PMID: 32198061
Improved synthesis of [18F] fallypride and characterization of a Huntington's disease mouse model, zQ175DN KI, using longitudinal PET imaging of D2/D3 receptors.
Huhtala T, Poutiainen P, Rytkönen J, Lehtimäki K, Parkkari T, Kasanen I, Airaksinen AJ, Koivula T, Sweeney P, Kontkanen O, Wityak J, Dominiquez C, Park LC. Huhtala T, et al. Among authors: rytkonen j. EJNMMI Radiopharm Chem. 2019 Aug 5;4(1):20. doi: 10.1186/s41181-019-0071-6. EJNMMI Radiopharm Chem. 2019. PMID: 31659519 Free PMC article.
Peptide labelling strategies for imaging agents.
Huhtala T, Weisell J, Rytkönen J, Närvänen A. Huhtala T, et al. Among authors: rytkonen j. Methods Mol Biol. 2014;1088:171-83. doi: 10.1007/978-1-62703-673-3_12. Methods Mol Biol. 2014. PMID: 24146404
Functionalization of alkyne-terminated thermally hydrocarbonized porous silicon nanoparticles with targeting peptides and antifouling polymers: effect on the human plasma protein adsorption.
Wang CF, Mäkilä EM, Bonduelle C, Rytkönen J, Raula J, Almeida S, Närvänen A, Salonen JJ, Lecommandoux S, Hirvonen JT, Santos HA. Wang CF, et al. Among authors: rytkonen j. ACS Appl Mater Interfaces. 2015 Jan 28;7(3):2006-15. doi: 10.1021/am507827n. Epub 2015 Jan 13. ACS Appl Mater Interfaces. 2015. PMID: 25539741
17 results