Ryu J - Search Results

1

LRG1 is an adipokine that mediates obesity-induced hepatosteatosis and insulin resistance.

He S, Ryu J, Liu J, Luo H, Lv Y, Langlais PR, Wen J, Dong F, Sun Z, Xia W, Lynch JL, Duggirala R, Nicholson BJ, Zang M, Shi Y, Zhang F, Liu F, Bai J, Dong LQ. He S, et al. Among authors: ryu j. J Clin Invest. 2021 Dec 15;131(24):e148545. doi: 10.1172/JCI148545. J Clin Invest. 2021. PMID: 34730111 Free PMC article.

2

Adiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent pathways.

Zhou L, Deepa SS, Etzler JC, Ryu J, Mao X, Fang Q, Liu DD, Torres JM, Jia W, Lechleiter JD, Liu F, Dong LQ. Zhou L, et al. Among authors: ryu j. J Biol Chem. 2009 Aug 14;284(33):22426-22435. doi: 10.1074/jbc.M109.028357. Epub 2009 Jun 11. J Biol Chem. 2009. PMID: 19520843 Free PMC article.

3

APPL1 mediates adiponectin-induced LKB1 cytosolic localization through the PP2A-PKCzeta signaling pathway.

Deepa SS, Zhou L, Ryu J, Wang C, Mao X, Li C, Zhang N, Musi N, DeFronzo RA, Liu F, Dong LQ. Deepa SS, et al. Among authors: ryu j. Mol Endocrinol. 2011 Oct;25(10):1773-85. doi: 10.1210/me.2011-0082. Epub 2011 Aug 11. Mol Endocrinol. 2011. PMID: 21835890 Free PMC article.

4

Proliferative and antiapoptotic signaling stimulated by nuclear-localized PDK1 results in oncogenesis.

Kikani CK, Verona EV, Ryu J, Shen Y, Ye Q, Zheng L, Qian Z, Sakaue H, Nakamura K, Du J, Ji Q, Ogawa W, Sun LZ, Dong LQ, Liu F. Kikani CK, et al. Among authors: ryu j. Sci Signal. 2012 Nov 6;5(249):ra80. doi: 10.1126/scisignal.2003065. Sci Signal. 2012. PMID: 23131847 Free PMC article.

5

Deficiency of APPL1 in mice impairs glucose-stimulated insulin secretion through inhibition of pancreatic beta cell mitochondrial function.

Wang C, Li X, Mu K, Li L, Wang S, Zhu Y, Zhang M, Ryu J, Xie Z, Shi D, Zhang WJ, Dong LQ, Jia W. Wang C, et al. Among authors: ryu j. Diabetologia. 2013 Sep;56(9):1999-2009. doi: 10.1007/s00125-013-2971-4. Epub 2013 Jun 22. Diabetologia. 2013. PMID: 23793716 Free PMC article.

6

APPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor.

Ryu J, Galan AK, Xin X, Dong F, Abdul-Ghani MA, Zhou L, Wang C, Li C, Holmes BM, Sloane LB, Austad SN, Guo S, Musi N, DeFronzo RA, Deng C, White MF, Liu F, Dong LQ. Ryu J, et al. Cell Rep. 2014 May 22;7(4):1227-38. doi: 10.1016/j.celrep.2014.04.006. Epub 2014 May 10. Cell Rep. 2014. PMID: 24813896 Free PMC article.

7

Alternative splicing variant of the scaffold protein APPL1 suppresses hepatic adiponectin signaling and function.

Galan-Davila AK, Ryu J, Dong K, Xiao Y, Dai Z, Zhang D, Li Z, Dick AM, Liu KD, Kamat A, Lu M, Dong Q, Liu F, Dong LQ. Galan-Davila AK, et al. Among authors: ryu j. J Biol Chem. 2018 Apr 20;293(16):6064-6074. doi: 10.1074/jbc.RA118.002162. Epub 2018 Feb 26. J Biol Chem. 2018. PMID: 29483192 Free PMC article.

8

Potential Roles of Adiponectin Isoforms in Human Obesity with Delayed Wound Healing.

Ryu J, Loza CA, Xu H, Zhou M, Hadley JT, Wu J, You H, Wang H, Yang J, Bai J, Liu F, Bialowas C, Dong LQ. Ryu J, et al. Cells. 2019 Sep 24;8(10):1134. doi: 10.3390/cells8101134. Cells. 2019. PMID: 31554182 Free PMC article.

9

Adiponectin Alleviates Diet-Induced Inflammation in the Liver by Suppressing MCP-1 Expression and Macrophage Infiltration.

Ryu J, Hadley JT, Li Z, Dong F, Xu H, Xin X, Zhang Y, Chen C, Li S, Guo X, Zhao JL, Leach RJ, Abdul-Ghani MA, DeFronzo RA, Kamat A, Liu F, Dong LQ. Ryu J, et al. Diabetes. 2021 Jun;70(6):1303-1316. doi: 10.2337/db20-1073. Epub 2021 Mar 18. Diabetes. 2021. PMID: 34162682 Free PMC article.

10

Upregulated TGF-β1 contributes to hyperglycaemia in type 2 diabetes by potentiating glucagon signalling.

Xiao Y, Wang Y, Ryu J, Liu W, Zou H, Zhang R, Yan Y, Dai Z, Zhang D, Sun LZ, Liu F, Zhou Z, Dong LQ. Xiao Y, et al. Among authors: ryu j. Diabetologia. 2023 Jun;66(6):1142-1155. doi: 10.1007/s00125-023-05889-5. Epub 2023 Mar 14. Diabetologia. 2023. PMID: 36917279

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