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Leptin resistance and diet-induced obesity: central and peripheral actions of leptin.
Sáinz N, Barrenetxe J, Moreno-Aliaga MJ, Martínez JA. Sáinz N, et al. Metabolism. 2015 Jan;64(1):35-46. doi: 10.1016/j.metabol.2014.10.015. Epub 2014 Oct 23. Metabolism. 2015. PMID: 25497342 Review.
The inhibitory effect of leptin on angiotensin II-induced vasoconstriction is blunted in spontaneously hypertensive rats.
Rodríguez A, Frühbeck G, Gómez-Ambrosi J, Catalán V, Sáinz N, Díez J, Zalba G, Fortuño A. Rodríguez A, et al. J Hypertens. 2006 Aug;24(8):1589-97. doi: 10.1097/01.hjh.0000239295.17636.6e. J Hypertens. 2006. PMID: 16877962
Acylated and desacyl ghrelin stimulate lipid accumulation in human visceral adipocytes.
Rodríguez A, Gómez-Ambrosi J, Catalán V, Gil MJ, Becerril S, Sáinz N, Silva C, Salvador J, Colina I, Frühbeck G. Rodríguez A, et al. Int J Obes (Lond). 2009 May;33(5):541-52. doi: 10.1038/ijo.2009.40. Epub 2009 Feb 24. Int J Obes (Lond). 2009. PMID: 19238155
BAT: a new target for human obesity?
Frühbeck G, Becerril S, Sáinz N, Garrastachu P, García-Velloso MJ. Frühbeck G, et al. Trends Pharmacol Sci. 2009 Aug;30(8):387-96. doi: 10.1016/j.tips.2009.05.003. Trends Pharmacol Sci. 2009. PMID: 19595466
Leptin administration favors muscle mass accretion by decreasing FoxO3a and increasing PGC-1alpha in ob/ob mice.
Sáinz N, Rodríguez A, Catalán V, Becerril S, Ramírez B, Gómez-Ambrosi J, Frühbeck G. Sáinz N, et al. PLoS One. 2009 Sep 4;4(9):e6808. doi: 10.1371/journal.pone.0006808. PLoS One. 2009. PMID: 19730740 Free PMC article.
Association of plasma acylated ghrelin with blood pressure and left ventricular mass in patients with metabolic syndrome.
Rodríguez A, Gómez-Ambrosi J, Catalán V, Becerril S, Sáinz N, Gil MJ, Silva C, Salvador J, Barba J, Colina I, Frühbeck G. Rodríguez A, et al. J Hypertens. 2010 Mar;28(3):560-7. doi: 10.1097/HJH.0b013e328334327c. J Hypertens. 2010. PMID: 19907342
Deletion of inducible nitric-oxide synthase in leptin-deficient mice improves brown adipose tissue function.
Becerril S, Rodríguez A, Catalán V, Sáinz N, Ramírez B, Collantes M, Peñuelas I, Gómez-Ambrosi J, Frühbeck G. Becerril S, et al. PLoS One. 2010 Jun 4;5(6):e10962. doi: 10.1371/journal.pone.0010962. PLoS One. 2010. PMID: 20532036 Free PMC article.
Leptin administration downregulates the increased expression levels of genes related to oxidative stress and inflammation in the skeletal muscle of ob/ob mice.
Sáinz N, Rodríguez A, Catalán V, Becerril S, Ramírez B, Gómez-Ambrosi J, Frühbeck G. Sáinz N, et al. Mediators Inflamm. 2010;2010:784343. doi: 10.1155/2010/784343. Epub 2010 Jun 30. Mediators Inflamm. 2010. PMID: 20671928 Free PMC article.
Leptin reduces the expression and increases the phosphorylation of the negative regulators of GLUT4 traffic TBC1D1 and TBC1D4 in muscle of ob/ob mice.
Sáinz N, Rodríguez A, Catalán V, Becerril S, Ramírez B, Lancha A, Burgos-Ramos E, Gómez-Ambrosi J, Frühbeck G. Sáinz N, et al. PLoS One. 2012;7(1):e29389. doi: 10.1371/journal.pone.0029389. Epub 2012 Jan 9. PLoS One. 2012. PMID: 22253718 Free PMC article.
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