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Cloning vectors, derived from a naturally occurring plasmid of Pseudomonas savastanoi, specifically tailored for genetic manipulations in Pseudomonas.
Nieto C, Fernández-Tresguerres E, Sánchez N, Vicente M, Díaz R. Nieto C, et al. Among authors: sanchez n. Gene. 1990 Mar 1;87(1):145-9. doi: 10.1016/0378-1119(90)90507-n. Gene. 1990. PMID: 2110095
Development of an AAV9 coding for a 3XFLAG-TALEfrat#8-VP64 able to increase in vivo the human frataxin in YG8R mice.
Chapdelaine P, Gérard C, Sanchez N, Cherif K, Rousseau J, Ouellet DL, Jauvin D, Tremblay JP. Chapdelaine P, et al. Among authors: sanchez n. Gene Ther. 2016 Jul;23(7):606-14. doi: 10.1038/gt.2016.36. Epub 2016 May 5. Gene Ther. 2016. PMID: 27082765 Free PMC article.
This TALEfrat#8 was fused with a 3XFLAG at its N terminal and a VP64 TAD at its C terminal, and driven by a CAG promoter. This AAV9_3XFLAG-TALEfrat#8-VP64 was injected intraperitoneally to 9-day-old and 4-month-old YG8R mice. ...
This TALEfrat#8 was fused with a 3XFLAG at its N terminal and a VP64 TAD at its C terminal, and driven by a CAG promoter. This AAV9_3 …
Characterization of frataxin gene network in Friedreich's ataxia fibroblasts using the RNA-Seq technique.
Sanchez N, Chapdelaine P, Rousseau J, Raymond F, Corbeil J, Tremblay JP. Sanchez N, et al. Mitochondrion. 2016 Sep;30:59-66. doi: 10.1016/j.mito.2016.06.003. Epub 2016 Jun 25. Mitochondrion. 2016. PMID: 27350085 No abstract available.
Programmed cell death in the neurulating embryo is prevented by the chaperone heat shock cognate 70.
Rubio E, Valenciano AI, Segundo C, Sánchez N, de Pablo F, de la Rosa EJ. Rubio E, et al. Among authors: sanchez n. Eur J Neurosci. 2002 May;15(10):1646-54. doi: 10.1046/j.1460-9568.2002.01998.x. Eur J Neurosci. 2002. PMID: 12059972
CHO cell culture longevity and recombinant protein yield are enhanced by depletion of miR-7 activity via sponge decoy vectors.
Sanchez N, Kelly P, Gallagher C, Lao NT, Clarke C, Clynes M, Barron N. Sanchez N, et al. Biotechnol J. 2014 Mar;9(3):396-404. doi: 10.1002/biot.201300325. Epub 2013 Dec 10. Biotechnol J. 2014. PMID: 24166820
A 6-month maintenance therapy with adapalene-benzoyl peroxide gel prevents relapse and continuously improves efficacy among patients with severe acne vulgaris: results of a randomized controlled trial.
Poulin Y, Sanchez NP, Bucko A, Fowler J, Jarratt M, Kempers S, Kerrouche N, Dhuin JC, Kunynetz R. Poulin Y, et al. Among authors: sanchez np. Br J Dermatol. 2011 Jun;164(6):1376-82. doi: 10.1111/j.1365-2133.2011.10344.x. Epub 2011 May 20. Br J Dermatol. 2011. PMID: 21457209 Clinical Trial.
MiR-7 triggers cell cycle arrest at the G1/S transition by targeting multiple genes including Skp2 and Psme3.
Sanchez N, Gallagher M, Lao N, Gallagher C, Clarke C, Doolan P, Aherne S, Blanco A, Meleady P, Clynes M, Barron N. Sanchez N, et al. PLoS One. 2013 Jun 6;8(6):e65671. doi: 10.1371/journal.pone.0065671. Print 2013. PLoS One. 2013. PMID: 23762407 Free PMC article.
Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate.
Clarke C, Henry M, Doolan P, Kelly S, Aherne S, Sanchez N, Kelly P, Kinsella P, Breen L, Madden SF, Zhang L, Leonard M, Clynes M, Meleady P, Barron N. Clarke C, et al. Among authors: sanchez n. BMC Genomics. 2012 Nov 21;13:656. doi: 10.1186/1471-2164-13-656. BMC Genomics. 2012. PMID: 23170974 Free PMC article.
Gene ontology (GO) analysis of genes (n=432) and proteins (n=285) found to be differentially expressed (DE) identified biological processes driving proliferation including mRNA processing and translation. ...The first set contained candidates where evidence of trans …
Gene ontology (GO) analysis of genes (n=432) and proteins (n=285) found to be differentially expressed (DE) identified biologi …
Impact of miR-7 over-expression on the proteome of Chinese hamster ovary cells.
Meleady P, Gallagher M, Clarke C, Henry M, Sanchez N, Barron N, Clynes M. Meleady P, et al. Among authors: sanchez n. J Biotechnol. 2012 Aug 31;160(3-4):251-62. doi: 10.1016/j.jbiotec.2012.03.002. Epub 2012 Mar 15. J Biotechnol. 2012. PMID: 22445466
MicroRNAs: tiny targets for engineering CHO cell phenotypes?
Barron N, Sanchez N, Kelly P, Clynes M. Barron N, et al. Among authors: sanchez n. Biotechnol Lett. 2011 Jan;33(1):11-21. doi: 10.1007/s10529-010-0415-5. Epub 2010 Sep 25. Biotechnol Lett. 2011. PMID: 20872159 Review.
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