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The mitochondrial ATPase inhibitory factor 1 triggers a ROS-mediated retrograde prosurvival and proliferative response.
Formentini L, Sánchez-Aragó M, Sánchez-Cenizo L, Cuezva JM. Formentini L, et al. Mol Cell. 2012 Mar 30;45(6):731-42. doi: 10.1016/j.molcel.2012.01.008. Epub 2012 Feb 16. Mol Cell. 2012. PMID: 22342343
Mitochondrial response to the BCKDK-deficiency: Some clues to understand the positive dietary response in this form of autism.
Oyarzabal A, Bravo-Alonso I, Sánchez-Aragó M, Rejas MT, Merinero B, García-Cazorla A, Artuch R, Ugarte M, Rodríguez-Pombo P. Oyarzabal A, et al. Among authors: sanchez arago m. Biochim Biophys Acta. 2016 Apr;1862(4):592-600. doi: 10.1016/j.bbadis.2016.01.016. Epub 2016 Jan 22. Biochim Biophys Acta. 2016. PMID: 26809120 Free article.
Mitochondrial bioenergetics and dynamics interplay in complex I-deficient fibroblasts.
Morán M, Rivera H, Sánchez-Aragó M, Blázquez A, Merinero B, Ugalde C, Arenas J, Cuezva JM, Martín MA. Morán M, et al. Biochim Biophys Acta. 2010 May;1802(5):443-53. doi: 10.1016/j.bbadis.2010.02.001. Epub 2010 Feb 11. Biochim Biophys Acta. 2010. PMID: 20153825
Expression, regulation and clinical relevance of the ATPase inhibitory factor 1 in human cancers.
Sánchez-Aragó M, Formentini L, Martínez-Reyes I, García-Bermudez J, Santacatterina F, Sánchez-Cenizo L, Willers IM, Aldea M, Nájera L, Juarránz A, López EC, Clofent J, Navarro C, Espinosa E, Cuezva JM. Sánchez-Aragó M, et al. Oncogenesis. 2013 Apr 22;2(4):e46. doi: 10.1038/oncsis.2013.9. Oncogenesis. 2013. PMID: 23608753 Free PMC article.
Degradation of IF1 controls energy metabolism during osteogenic differentiation of stem cells.
Sánchez-Aragó M, García-Bermúdez J, Martínez-Reyes I, Santacatterina F, Cuezva JM. Sánchez-Aragó M, et al. EMBO Rep. 2013 Jul;14(7):638-44. doi: 10.1038/embor.2013.72. Epub 2013 May 31. EMBO Rep. 2013. PMID: 23722655 Free PMC article.
Adalimumab Reduces Photoreceptor Cell Death in A Mouse Model of Retinal Degeneration.
Martínez-Fernández de la Cámara C, Hernández-Pinto AM, Olivares-González L, Cuevas-Martín C, Sánchez-Aragó M, Hervás D, Salom D, Cuezva JM, de la Rosa EJ, Millán JM, Rodrigo R. Martínez-Fernández de la Cámara C, et al. Among authors: sanchez arago m. Sci Rep. 2015 Jul 14;5:11764. doi: 10.1038/srep11764. Sci Rep. 2015. PMID: 26170250 Free PMC article.
Pyruvate kinase M2 and the mitochondrial ATPase Inhibitory Factor 1 provide novel biomarkers of dermatomyositis: a metabolic link to oncogenesis.
Santacatterina F, Sánchez-Aragó M, Catalán-García M, Garrabou G, de Arenas CN, Grau JM, Cardellach F, Cuezva JM. Santacatterina F, et al. Among authors: sanchez arago m. J Transl Med. 2017 Feb 10;15(1):29. doi: 10.1186/s12967-017-1136-5. J Transl Med. 2017. PMID: 28183315 Free PMC article.
PKA Phosphorylates the ATPase Inhibitory Factor 1 and Inactivates Its Capacity to Bind and Inhibit the Mitochondrial H(+)-ATP Synthase.
García-Bermúdez J, Sánchez-Aragó M, Soldevilla B, Del Arco A, Nuevo-Tapioles C, Cuezva JM. García-Bermúdez J, et al. Among authors: sanchez arago m. Cell Rep. 2015 Sep 29;12(12):2143-55. doi: 10.1016/j.celrep.2015.08.052. Epub 2015 Sep 17. Cell Rep. 2015. PMID: 26387949 Free article.
Hif-1α Knockdown Reduces Glycolytic Metabolism and Induces Cell Death of Human Synovial Fibroblasts Under Normoxic Conditions.
Del Rey MJ, Valín Á, Usategui A, García-Herrero CM, Sánchez-Aragó M, Cuezva JM, Galindo M, Bravo B, Cañete JD, Blanco FJ, Criado G, Pablos JL. Del Rey MJ, et al. Among authors: sanchez arago m. Sci Rep. 2017 Jun 16;7(1):3644. doi: 10.1038/s41598-017-03921-4. Sci Rep. 2017. PMID: 28623342 Free PMC article.
Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic state.
Santacatterina F, Sánchez-Cenizo L, Formentini L, Mobasher MA, Casas E, Rueda CB, Martínez-Reyes I, Núñez de Arenas C, García-Bermúdez J, Zapata JM, Sánchez-Aragó M, Satrústegui J, Valverde ÁM, Cuezva JM. Santacatterina F, et al. Among authors: sanchez arago m. Oncotarget. 2016 Jan 5;7(1):490-508. doi: 10.18632/oncotarget.6357. Oncotarget. 2016. PMID: 26595676 Free PMC article.
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