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Nucleocytoplasmic shuttling of the GPN-loop GTPase Gpn3 is regulated by serum and cell density in MCF-12A mammary cells.
Peña-Gómez SG, Cristóbal-Mondragón GR, Vega-Palomo CR, Mora-García M, Félix-Pérez T, Rebolloso-Gómez Y, Calera MR, Sánchez-Olea R. Peña-Gómez SG, et al. Among authors: sanchez olea r. Biochim Biophys Acta Mol Cell Res. 2024 Mar;1871(3):119685. doi: 10.1016/j.bbamcr.2024.119685. Epub 2024 Feb 10. Biochim Biophys Acta Mol Cell Res. 2024. PMID: 38342311
Synthetic negative genome screen of the GPN-loop GTPase NPA3 in Saccharomyces cerevisiae.
Mora-García M, Ascencio D, Félix-Pérez T, Ulloa-Calzonzin J, Juárez-Reyes A, Robledo-Márquez K, Rebolloso-Gómez Y, Riego-Ruiz L, DeLuna A, Calera MR, Sánchez-Olea R. Mora-García M, et al. Among authors: sanchez olea r. Curr Genet. 2022 Aug;68(3-4):343-360. doi: 10.1007/s00294-022-01243-1. Epub 2022 Jun 4. Curr Genet. 2022. PMID: 35660944
FRET-based analysis and molecular modeling of the human GPN-loop GTPases 1 and 3 heterodimer unveils a dominant-negative protein complex.
Cristóbal-Mondragón GR, Lara-Chacón B, Santiago Á, De-la-Rosa V, González-González R, Muñiz-Luna JA, Ladrón-de-Guevara E, Romero-Romero S, Rangel-Yescas GE, Fernández Velasco DA, Islas LD, Pastor N, Sánchez-Olea R, Calera MR. Cristóbal-Mondragón GR, et al. Among authors: sanchez olea r. FEBS J. 2019 Dec;286(23):4797-4818. doi: 10.1111/febs.14996. Epub 2019 Jul 22. FEBS J. 2019. PMID: 31298811 Free article.
The Gpn3 Q279* cancer-associated mutant inhibits Gpn1 nuclear export and is deficient in RNA polymerase II nuclear targeting.
Barbosa-Camacho AA, Méndez-Hernández LE, Lara-Chacón B, Peña-Gómez SG, Romero V, González-González R, Guerra-Moreno JA, Robledo-Rivera AY, Sánchez-Olea R, Calera MR. Barbosa-Camacho AA, et al. Among authors: sanchez olea r. FEBS Lett. 2017 Nov;591(21):3555-3566. doi: 10.1002/1873-3468.12856. Epub 2017 Oct 11. FEBS Lett. 2017. PMID: 28940195 Free article.
Human Gpn1 purified from bacteria binds guanine nucleotides and hydrolyzes GTP as a protein dimer stabilized by its C-terminal tail.
González-González R, Guerra-Moreno JA, Cristóbal-Mondragón GR, Romero V, Peña-Gómez SG, Montero-Morán GM, Lara-González S, Hernández-Arana A, Fernández-Velasco DA, Calera MR, Sánchez-Olea R. González-González R, et al. Among authors: sanchez olea r. Protein Expr Purif. 2017 Apr;132:85-96. doi: 10.1016/j.pep.2017.01.009. Epub 2017 Jan 30. Protein Expr Purif. 2017. PMID: 28153773
Npa3/ScGpn1 carboxy-terminal tail is dispensable for cell viability and RNA polymerase II nuclear targeting but critical for microtubule stability and function.
Guerrero-Serrano G, Castanedo L, Cristóbal-Mondragón GR, Montalvo-Arredondo J, Riego-Ruíz L, DeLuna A, De Las Peñas A, Castaño I, Calera MR, Sánchez-Olea R. Guerrero-Serrano G, et al. Among authors: sanchez olea r. Biochim Biophys Acta Mol Cell Res. 2017 Mar;1864(3):451-462. doi: 10.1016/j.bbamcr.2016.12.010. Epub 2016 Dec 10. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 27965115 Free article.
Gpn1 and Gpn3 associate tightly and their protein levels are mutually dependent in mammalian cells.
Méndez-Hernández LE, Pérez-Mejía AE, Lara-Chacón B, Barbosa-Camacho AA, Peña-Gómez SG, Martínez-Sánchez M, Robledo-Rivera AY, Sánchez-Olea R, Calera MR. Méndez-Hernández LE, et al. Among authors: sanchez olea r. FEBS Lett. 2014 Nov 3;588(21):3823-9. doi: 10.1016/j.febslet.2014.08.038. Epub 2014 Sep 19. FEBS Lett. 2014. PMID: 25241168 Free article.
44 results