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Sequential inductions of the ZEB1 transcription factor caused by mutation of Rb and then Ras proteins are required for tumor initiation and progression.
Liu Y, Sánchez-Tilló E, Lu X, Huang L, Clem B, Telang S, Jenson AB, Cuatrecasas M, Chesney J, Postigo A, Dean DC. Liu Y, et al. Among authors: sanchez tillo e. J Biol Chem. 2013 Apr 19;288(16):11572-80. doi: 10.1074/jbc.M112.434951. Epub 2013 Feb 26. J Biol Chem. 2013. PMID: 23443660 Free PMC article.
Rb1 family mutation is sufficient for sarcoma initiation.
Liu Y, Sánchez-Tilló E, Lu X, Clem B, Telang S, Jenson AB, Cuatrecasas M, Chesney J, Postigo A, Dean DC. Liu Y, et al. Among authors: sanchez tillo e. Nat Commun. 2013;4:2650. doi: 10.1038/ncomms3650. Nat Commun. 2013. PMID: 24150016 Free article.
28 results