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Divergent role of heme oxygenase inhibition in the pathogenesis of sepsis.
Freitas A, Alves-Filho JC, Trevelin SC, Spiller F, Suavinha MM, Nascimento DC, Pestana CR, Dal-Secco D, Sônego F, Czaikoski PG, Curti C, Barja-Fidalgo C, Cunha FQ. Freitas A, et al. Among authors: sonego f. Shock. 2011 Jun;35(6):550-9. doi: 10.1097/SHK.0b013e31820e1ef0. Shock. 2011. PMID: 21330952
Heme oxygenase inhibition enhances neutrophil migration into the bronchoalveolar spaces and improves the outcome of murine pneumonia-induced sepsis.
Czaikoski PG, Nascimento DC, Sônego F, de Freitas A, Turato WM, de Carvalho MA, Santos RS, de Oliveira GP, dos Santos Samary C, Tefe-Silva C, Alves-Filho JC, Ferreira SH, Rossi MA, Rocco PR, Spiller F, Cunha FQ. Czaikoski PG, et al. Among authors: sonego f. Shock. 2013 Apr;39(4):389-96. doi: 10.1097/SHK.0b013e31828bbcf9. Shock. 2013. PMID: 23481491
Targeting neutrophils in sepsis.
Sônego F, Alves-Filho JC, Cunha FQ. Sônego F, et al. Expert Rev Clin Immunol. 2014 Aug;10(8):1019-28. doi: 10.1586/1744666X.2014.922876. Epub 2014 May 28. Expert Rev Clin Immunol. 2014. PMID: 24867165 Review.
MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response.
Sônego F, Castanheira FV, Czaikoski PG, Kanashiro A, Souto FO, França RO, Nascimento DC, Freitas A, Spiller F, Cunha LD, Zamboni DS, Alves-Filho JC, Cunha FQ. Sônego F, et al. PLoS One. 2014 Aug 1;9(8):e103734. doi: 10.1371/journal.pone.0103734. eCollection 2014. PLoS One. 2014. PMID: 25084278 Free PMC article.
Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis.
Czaikoski PG, Mota JM, Nascimento DC, Sônego F, Castanheira FV, Melo PH, Scortegagna GT, Silva RL, Barroso-Sousa R, Souto FO, Pazin-Filho A, Figueiredo F, Alves-Filho JC, Cunha FQ. Czaikoski PG, et al. Among authors: sonego f. PLoS One. 2016 Feb 5;11(2):e0148142. doi: 10.1371/journal.pone.0148142. eCollection 2016. PLoS One. 2016. PMID: 26849138 Free PMC article.
Therapeutic potential and limitations of cholinergic anti-inflammatory pathway in sepsis.
Kanashiro A, Sônego F, Ferreira RG, Castanheira FV, Leite CA, Borges VF, Nascimento DC, Cólon DF, Alves-Filho JC, Ulloa L, Cunha FQ. Kanashiro A, et al. Among authors: sonego f. Pharmacol Res. 2017 Mar;117:1-8. doi: 10.1016/j.phrs.2016.12.014. Epub 2016 Dec 12. Pharmacol Res. 2017. PMID: 27979692 Free PMC article. Review.
39 results