Cholinergic patterns correlate with dopamine medication ON freezing of gait in Parkinson's disease.
Hvingelby VS, Terkelsen MH, Johnsen EL, Møller M, Danielsen EH, Henriksen T, Glud AN, Tai YF, Møller Andersen AS, Knudsen AL, Meier K, Horsager J, Okkels N, Sørensen JCH, Borghammer P, Moro E, Pavese N.
Hvingelby VS, et al. Among authors: sorensen jch.
Brain. 2025 Dec 4;148(12):4508-4518. doi: 10.1093/brain/awaf231.
Brain. 2025.
PMID: 40512756
The causative pathophysiology is not completely understood. In this study, PET with 18F-fluoroethoxybenzovesamicol (18F-FEOBV), a presynaptic marker of cholinergic terminal density, and 18F-fluorodeoxyglucose (18F-FDG) was performed in a cohort of people with Parkinson's d …
The causative pathophysiology is not completely understood. In this study, PET with 18F-fluoroethoxybenzovesamicol (18F-FEOBV), a pre …