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Optimal reference genes for normalization of qRT-PCR data from archival formalin-fixed, paraffin-embedded breast tumors controlling for tumor cell content and decay of mRNA.
Tramm T, Sørensen BS, Overgaard J, Alsner J. Tramm T, et al. Diagn Mol Pathol. 2013 Sep;22(3):181-7. doi: 10.1097/PDM.0b013e318285651e. Diagn Mol Pathol. 2013. PMID: 23846446
Proteins upregulated by mild and severe hypoxia in squamous cell carcinomas in vitro identified by proteomics.
Sørensen BS, Horsman MR, Vorum H, Honoré B, Overgaard J, Alsner J. Sørensen BS, et al. Radiother Oncol. 2009 Sep;92(3):443-9. doi: 10.1016/j.radonc.2009.05.019. Epub 2009 Jun 21. Radiother Oncol. 2009. PMID: 19541378
Gene expression classifier predicts for hypoxic modification of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck.
Toustrup K, Sørensen BS, Lassen P, Wiuf C, Alsner J, Overgaard J; Danish Head and Neck Cancer Group (DAHANCA). Toustrup K, et al. Radiother Oncol. 2012 Jan;102(1):122-9. doi: 10.1016/j.radonc.2011.09.010. Epub 2011 Oct 11. Radiother Oncol. 2012. PMID: 21996521 Clinical Trial.
Identification of accurate reference genes for RT-qPCR analysis of formalin-fixed paraffin-embedded tissue from primary non-small cell lung cancers and brain and lymph node metastases.
Søes S, Sørensen BS, Alsner J, Overgaard J, Hager H, Hansen LL, Kristensen LS. Søes S, et al. Lung Cancer. 2013 Aug;81(2):180-6. doi: 10.1016/j.lungcan.2013.04.007. Epub 2013 May 3. Lung Cancer. 2013. PMID: 23643276
The importance of reference gene analysis of formalin-fixed, paraffin-embedded samples from sarcoma patients - an often underestimated problem.
Aggerholm-Pedersen N, Safwat A, Bærentzen S, Nordsmark M, Nielsen OS, Alsner J, Sørensen BS. Aggerholm-Pedersen N, et al. Transl Oncol. 2014 Dec;7(6):687-93. doi: 10.1016/j.tranon.2014.09.012. Transl Oncol. 2014. PMID: 25500077 Free PMC article.
The usability of a 15-gene hypoxia classifier as a universal hypoxia profile in various cancer cell types.
Sørensen BS, Knudsen A, Wittrup CF, Nielsen S, Aggerholm-Pedersen N, Busk M, Horsman M, Høyer M, Bouchelouche PN, Overgaard J, Alsner J. Sørensen BS, et al. Radiother Oncol. 2015 Sep;116(3):346-51. doi: 10.1016/j.radonc.2015.06.028. Epub 2015 Jul 10. Radiother Oncol. 2015. PMID: 26169282
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