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Synthesis of Derivatives of the Antibiotic Albicidin: The N-Terminal Fragment as Key to Control Potency and Resistance Mediated by the Binding Protein AlbA.
Kulike-Koczula M, Hommernick K, Ghimire LB, Kosol S, Zborovsky L, Seidel M, Sattler N, Mainz A, Weston JB, Ghilarov D, Süssmuth RD. Kulike-Koczula M, et al. Among authors: sussmuth rd. Chemistry. 2025 Apr 9;31(21):e202500162. doi: 10.1002/chem.202500162. Epub 2025 Mar 11. Chemistry. 2025. PMID: 40024889 Free PMC article.
A fluorometric assay to determine labile copper(II) ions in serum.
Maares M, Haupt A, Schüßler C, Kulike-Koczula M, Hackler J, Keil C, Mohr I, Schomburg L, Süssmuth RD, Zischka H, Merle U, Haase H. Maares M, et al. Sci Rep. 2023 Aug 7;13(1):12807. doi: 10.1038/s41598-023-39841-9. Sci Rep. 2023. PMID: 37550465 Free PMC article.
Gene amplifications cause high-level resistance against albicidin in gram-negative bacteria.
Saathoff M, Kosol S, Semmler T, Tedin K, Dimos N, Kupke J, Seidel M, Ghazisaeedi F, Jonske MC, Wolf SA, Kuropka B, Czyszczoń W, Ghilarov D, Grätz S, Heddle JG, Loll B, Süssmuth RD, Fulde M. Saathoff M, et al. PLoS Biol. 2023 Aug 10;21(8):e3002186. doi: 10.1371/journal.pbio.3002186. eCollection 2023 Aug. PLoS Biol. 2023. PMID: 37561817 Free PMC article.
Convergent evolution of antibiotic resistance mechanisms between pyrrolobenzodiazepines and albicidin in multidrug resistant Klebsiella pneumoniae.
Surani YM, Wand ME, Picconi P, Di Palma M, Zenezini Chiozzi R, Hasan MM, Andriollo P, Grätz S, Nahar KS, Maynard-Smith M, Süssmuth RD, Steiner RA, Rahman KM, Hind CK, Sutton JM. Surani YM, et al. Among authors: sussmuth rd. NPJ Antimicrob Resist. 2025 Jun 6;3(1):52. doi: 10.1038/s44259-025-00104-4. NPJ Antimicrob Resist. 2025. PMID: 40481275 Free PMC article.
254 results