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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1985 1
1987 1
1990 2
1991 2
1992 1
1993 1
1994 2
1995 4
1996 2
1997 3
1998 3
1999 7
2000 5
2001 5
2002 5
2003 4
2004 8
2005 11
2006 12
2007 8
2008 13
2009 13
2010 9
2011 15
2012 17
2013 12
2014 8
2015 20
2016 17
2017 13
2018 21
2019 16
2020 20
2021 10
2022 12
2023 4
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263 results
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Page 1
Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease.
Zeitler B, Froelich S, Marlen K, Shivak DA, Yu Q, Li D, Pearl JR, Miller JC, Zhang L, Paschon DE, Hinkley SJ, Ankoudinova I, Lam S, Guschin D, Kopan L, Cherone JM, Nguyen HB, Qiao G, Ataei Y, Mendel MC, Amora R, Surosky R, Laganiere J, Vu BJ, Narayanan A, Sedaghat Y, Tillack K, Thiede C, Gärtner A, Kwak S, Bard J, Mrzljak L, Park L, Heikkinen T, Lehtimäki KK, Svedberg MM, Häggkvist J, Tari L, Tóth M, Varrone A, Halldin C, Kudwa AE, Ramboz S, Day M, Kondapalli J, Surmeier DJ, Urnov FD, Gregory PD, Rebar EJ, Muñoz-Sanjuán I, Zhang HS. Zeitler B, et al. Among authors: halldin c. Nat Med. 2019 Jul;25(7):1131-1142. doi: 10.1038/s41591-019-0478-3. Epub 2019 Jul 1. Nat Med. 2019. PMID: 31263285
Huntington's disease (HD) is a dominantly inherited neurodegenerative disorder caused by a CAG trinucleotide expansion in the huntingtin gene (HTT), which codes for the pathologic mutant HTT (mHTT) protein. ...
Huntington's disease (HD) is a dominantly inherited neurodegenerative disorder caused by a CAG trinucleotide expansion in the hunting …
Dealing with PET radiometabolites.
Ghosh KK, Padmanabhan P, Yang CT, Mishra S, Halldin C, Gulyás B. Ghosh KK, et al. Among authors: halldin c. EJNMMI Res. 2020 Sep 23;10(1):109. doi: 10.1186/s13550-020-00692-4. EJNMMI Res. 2020. PMID: 32997213 Free PMC article. Review.
From a radiopharmaceutical perspective, it is necessary to quantify the parent radiotracer's fraction present in the tissue. Hence, the identification of radiometabolites of the radiotracers is vital for PET imaging. ...
From a radiopharmaceutical perspective, it is necessary to quantify the parent radiotracer's fraction present in the tissue. Hence, t …
RSA in Spine: A Review.
Humadi A, Dawood S, Halldin K, Freeman B. Humadi A, et al. Among authors: halldin k. Global Spine J. 2017 Dec;7(8):811-820. doi: 10.1177/2192568217701722. Epub 2017 Jul 28. Global Spine J. 2017. PMID: 29238647 Free PMC article. Review.
Comparative evaluations of norepinephrine transporter radioligands with reference tissue models in rhesus monkeys: (S,S)-[18F]FMeNER-D2 and (S,S)-[11C]MeNER.
Takano A, Gulyás B, Varrone A, Halldin C. Takano A, et al. Among authors: halldin c. Eur J Nucl Med Mol Imaging. 2009 Nov;36(11):1885-91. doi: 10.1007/s00259-009-1194-x. Epub 2009 Jun 30. Eur J Nucl Med Mol Imaging. 2009. PMID: 19565240
PURPOSE: Although two norepinephrine transporter (NET) radioligands, (S,S)-[(18)F]FMeNER-D(2) and (S,S)-[(11)C]MeNER, have been reported to have different characteristics, there has not been a direct comparative study in vivo. ...The regional BP(ND) va …
PURPOSE: Although two norepinephrine transporter (NET) radioligands, (S,S)-[(18)F]FMeNER-D(2) and (S,S)-[(11)C]M …
PET-MR and SPECT-MR multimodality probes: Development and challenges.
Yang CT, Ghosh KK, Padmanabhan P, Langer O, Liu J, Eng DNC, Halldin C, Gulyás B. Yang CT, et al. Among authors: halldin c. Theranostics. 2018 Nov 29;8(22):6210-6232. doi: 10.7150/thno.26610. eCollection 2018. Theranostics. 2018. PMID: 30613293 Free PMC article. Review.
Simplified and accessible [18 F]F-AraG synthesis procedure for preclinical PET.
Högnäsbacka AA, Cortés González MA, Halldin C, Schou M. Högnäsbacka AA, et al. Among authors: halldin c. J Labelled Comp Radiopharm. 2022 Aug;65(10-11):288-291. doi: 10.1002/jlcr.3997. Epub 2022 Aug 23. J Labelled Comp Radiopharm. 2022. PMID: 35980801 Free PMC article.
The PET tracer [(18) F]F-AraG, an arabinosyl guanine analog, has shown promise for visualizing activated T cells in multiple diseases. Herein, a practitioner's protocol is described, in which the PET tracer is prepared using minimal equipment and manual actions, making it …
The PET tracer [(18) F]F-AraG, an arabinosyl guanine analog, has shown promise for visualizing activated T cells in multiple diseases. Herei …
Investigation of the metabolites of (S,S)-[(11)C]MeNER in humans, monkeys and rats.
Schou M, Zoghbi SS, Shetty HU, Shchukin E, Liow JS, Hong J, Andrée BA, Gulyás B, Farde L, Innis RB, Pike VW, Halldin C. Schou M, et al. Among authors: halldin c. Mol Imaging Biol. 2009 Jan-Feb;11(1):23-30. doi: 10.1007/s11307-008-0175-y. Epub 2008 Sep 18. Mol Imaging Biol. 2009. PMID: 18800204 Free PMC article.
INTRODUCTION: (S,S)-[(11)C]MeNER ((S,S)-2-(alpha-(2-[(11)C]methoxyphenoxy)benzyl)morpholine) is a positron emission tomography (PET) radioligand recently applied in clinical studies of norepinephrine transporters (NETs) in the human brain in vivo. In v …
INTRODUCTION: (S,S)-[(11)C]MeNER ((S,S)-2-(alpha-(2-[(11)C]methoxyphenoxy)benzyl)morpholine) is a positron emiss …
Decreased 5-HT1A binding in mild Alzheimer's disease-A positron emission tomography study.
Mattsson P, Cselényi Z, Andrée B, Borg J, Nag S, Halldin C, Farde L. Mattsson P, et al. Among authors: halldin c. Synapse. 2022 Jun;76(7-8):e22235. doi: 10.1002/syn.22235. Epub 2022 May 28. Synapse. 2022. PMID: 35587913 Free PMC article.
Decreased 5-HT(1A) receptor binding has been associated with Alzheimer's disease (AD) and interpreted as a consequence of neuron loss. ...Wavelet-aided parametric images of nondisplaceable binding potential (BP(ND) ) were generated using Logan's graphical analysis w …
Decreased 5-HT(1A) receptor binding has been associated with Alzheimer's disease (AD) and interpreted as a consequence of neuron loss …
New developments of dopaminergic imaging in Parkinson's disease.
Varrone A, Halldin C. Varrone A, et al. Among authors: halldin c. Q J Nucl Med Mol Imaging. 2012 Feb;56(1):68-82. Q J Nucl Med Mol Imaging. 2012. PMID: 22460161 Review.
The development of radioligands for the dopaminergic system has provided suitable imaging biomarkers for clinical research in Parkinson's disease (PD) and related movement disorders. Single photon emission tomography (SPECT) has played an important role as main molecular i …
The development of radioligands for the dopaminergic system has provided suitable imaging biomarkers for clinical research in Parkinson's …
263 results