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Development of a multi-residue high-throughput UHPLC-MS/MS method for routine monitoring of SARM compounds in equine and bovine blood.
Ventura E, Gadaj A, Buckley T, Mooney MH. Ventura E, et al. Drug Test Anal. 2020 Sep;12(9):1373-1379. doi: 10.1002/dta.2875. Epub 2020 Jun 24. Drug Test Anal. 2020. PMID: 32519780
The current research describes for the first time the development of a semi-quantitative assay for the monitoring of SARM family compounds in blood and establishes the relative stability of these analytes under various storage conditions prior to analysis. ...The developed …
The current research describes for the first time the development of a semi-quantitative assay for the monitoring of SARM family comp …
A screening method for the quantitative determination of selective androgen receptor modulators (SARMs) in capsules by high resolution 19F- and 1H-NMR spectroscopy.
Maccelli A, Borioni A, Aureli F, Gaudiano MC, Manna L, Raimondo M. Maccelli A, et al. Anal Methods. 2024 Apr 4;16(14):2135-2146. doi: 10.1039/d4ay00188e. Anal Methods. 2024. PMID: 38517236
The statistical analysis of the results from (19)F- and (1)H-quantitative NMR showed that both approaches were equally effective, thus expanding the potential use of the methodology to non-fluorinated SARMs. At present, no SARM has been approved for human consumption; howe …
The statistical analysis of the results from (19)F- and (1)H-quantitative NMR showed that both approaches were equally effective, thus expan …
Characterization of in vitro generated metabolites of the selective androgen receptor modulators S-22 and S-23 and in vivo comparison to post-administration canine urine specimens.
Thevis M, Gerace E, Thomas A, Beuck S, Geyer H, Schlörer N, Kearbey JD, Dalton JT, Schänzer W. Thevis M, et al. Drug Test Anal. 2010 Nov-Dec;2(11-12):589-98. doi: 10.1002/dta.211. Epub 2010 Oct 22. Drug Test Anal. 2010. PMID: 20967890
Selective androgen receptor modulators (SARMs) have great therapeutic potential in various diseases including cancer cachexia, sarcopenia, and osteoporosis, and the number of drug candidates has been growing over the last decade. The SARM drug candidates S-22 and S-23 belo …
Selective androgen receptor modulators (SARMs) have great therapeutic potential in various diseases including cancer cachexia, sarcopenia, a …