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The following term was not found in PubMed: NP2-D8
Page 1
Molecular characterization of SARS-CoV-2 nucleocapsid protein.
Huang Y, Chen J, Chen S, Huang C, Li B, Li J, Jin Z, Zhang Q, Pan P, Du W, Liu L, Liu Z. Huang Y, et al. Front Cell Infect Microbiol. 2024 May 23;14:1415885. doi: 10.3389/fcimb.2024.1415885. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38846351 Free PMC article. Review.
The Nucleocapsid Protein (N protein) of SARS-CoV-2 is highly conserved in virus evolution and is involved in the key process of viral infection and assembly. ...This article reviews the research progress on the structure and biological function …
The Nucleocapsid Protein (N protein) of SARS-CoV-2 is highly conserved in virus evolution and is involved …
SARS-CoV-2 nucleocapsid protein interaction with YBX1 displays oncolytic properties through PKM mRNA destabilization.
Chen X, Jiang B, Gu Y, Yue Z, Liu Y, Lei Z, Yang G, Deng M, Zhang X, Luo Z, Li Y, Zhang Q, Zhang X, Wu J, Huang C, Pan P, Zhou F, Wang N. Chen X, et al. Mol Cancer. 2024 Nov 6;23(1):248. doi: 10.1186/s12943-024-02153-1. Mol Cancer. 2024. PMID: 39506849 Free PMC article.
Several cancer proliferation or metastasis related genes were frequently downregulated in SARS-CoV-2 infected intestinal organoids and human colon carcinoma cells. In vivo and in vitro studies revealed that SARS-CoV-2 nucleocapsid …
Several cancer proliferation or metastasis related genes were frequently downregulated in SARS-CoV-2 infected intestina …
SARS-CoV-2 N protein recruits G3BP to double membrane vesicles to promote translation of viral mRNAs.
Long S, Guzyk M, Perez Vidakovics L, Han X, Sun R, Wang M, Panas MD, Urgard E, Coquet JM, Merits A, Achour A, McInerney GM. Long S, et al. Nat Commun. 2024 Dec 5;15(1):10607. doi: 10.1038/s41467-024-54996-3. Nat Commun. 2024. PMID: 39638802 Free PMC article.
To study the impact of the G3BP-N interaction on viral replication and pathogenesis in detail, we generated a mutant SARS-CoV-2 (RATA) that specifically lacks the G3BP-binding motif in the N protein. ...This work provides a fuller understanding …
To study the impact of the G3BP-N interaction on viral replication and pathogenesis in detail, we generated a mutant SARS-C …
The utility of SARS-CoV-2 nucleocapsid protein in laboratory diagnosis.
Li X, Xiong M, Deng Q, Guo X, Li Y. Li X, et al. J Clin Lab Anal. 2022 Jul;36(7):e24534. doi: 10.1002/jcla.24534. Epub 2022 Jun 3. J Clin Lab Anal. 2022. PMID: 35657146 Free PMC article. Review.
BACKGROUND: The Coronavirus Disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has now become a global pandemic owing to its high transmissibility. The SARS-CoV-2 nucleoc …
BACKGROUND: The Coronavirus Disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS- …
Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis.
Johnson BA, Zhou Y, Lokugamage KG, Vu MN, Bopp N, Crocquet-Valdes PA, Kalveram B, Schindewolf C, Liu Y, Scharton D, Plante JA, Xie X, Aguilar P, Weaver SC, Shi PY, Walker DH, Routh AL, Plante KS, Menachery VD. Johnson BA, et al. PLoS Pathog. 2022 Jun 21;18(6):e1010627. doi: 10.1371/journal.ppat.1010627. eCollection 2022 Jun. PLoS Pathog. 2022. PMID: 35728038 Free PMC article.
While SARS-CoV-2 continues to adapt for human infection and transmission, genetic variation outside of the spike gene remains largely unexplored. This study investigates a highly variable region at residues 203-205 in the SARS-CoV-2 nu …
While SARS-CoV-2 continues to adapt for human infection and transmission, genetic variation outside of the spike gene r …
ISGylation of the SARS-CoV-2 N protein by HERC5 impedes N oligomerization and thereby viral RNA synthesis.
Zhu J, Liu G, Sayyad Z, Goins CM, Stauffer SR, Gack MU. Zhu J, et al. J Virol. 2024 Sep 17;98(9):e0086924. doi: 10.1128/jvi.00869-24. Epub 2024 Aug 28. J Virol. 2024. PMID: 39194248 Free PMC article.
In this study, we identified the nucleocapsid (N) protein of SARS-CoV-2 as a major substrate of ISGylation catalyzed by the host E3 ligase HERC5; however, N ISGylation is readily removed through deISGylation by the papain-like protease (P …
In this study, we identified the nucleocapsid (N) protein of SARS-CoV-2 as a major substrate of ISGylatio …
Suramin inhibits SARS-CoV-2 nucleocapsid phosphoprotein genome packaging function.
Boniardi I, Corona A, Basquin J, Basquin C, Milia J, Nagy I, Tramontano E, Zinzula L. Boniardi I, et al. Virus Res. 2023 Oct 15;336:199221. doi: 10.1016/j.virusres.2023.199221. Epub 2023 Sep 15. Virus Res. 2023. PMID: 37704176 Free PMC article.
The coronavirus disease 2019 (COVID-19) pandemic is fading, however its etiologic agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues posing - despite the availability of licensed vaccines - a global health threat, due to the p …
The coronavirus disease 2019 (COVID-19) pandemic is fading, however its etiologic agent severe acute respiratory syndrome coronavirus 2 …
Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2.
Wang YT, Long XY, Ding X, Fan SR, Cai JY, Yang BJ, Zhang XF, Luo RH, Yang L, Ruan T, Ren J, Jing CX, Zheng YT, Hao XJ, Chen DZ. Wang YT, et al. Eur J Med Chem. 2022 Jan 5;227:113966. doi: 10.1016/j.ejmech.2021.113966. Epub 2021 Nov 1. Eur J Med Chem. 2022. PMID: 34749200 Free PMC article.
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unprecedented in human history. As a major structural protein, nucleocapsid protein (NPro) is critical to the replication of SARS-CoV- …
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unprecedented in …
The Role of SARS-CoV-2 Nucleocapsid Protein in Host Inflammation.
Cao Y, Wang Y, Huang D, Tan YJ. Cao Y, et al. Viruses. 2025 Jul 27;17(8):1046. doi: 10.3390/v17081046. Viruses. 2025. PMID: 40872762 Free PMC article. Review.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has posed substantial health threats and triggered widespread global economic disruption. The nucleocapsid (N) prote …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (C …
Biochemical characterization of SARS-CoV-2 nucleocapsid protein.
Zeng W, Liu G, Ma H, Zhao D, Yang Y, Liu M, Mohammed A, Zhao C, Yang Y, Xie J, Ding C, Ma X, Weng J, Gao Y, He H, Jin T. Zeng W, et al. Biochem Biophys Res Commun. 2020 Jun 30;527(3):618-623. doi: 10.1016/j.bbrc.2020.04.136. Epub 2020 Apr 30. Biochem Biophys Res Commun. 2020. PMID: 32416961 Free PMC article.
The nucleocapsid (N) protein is an important antigen for coronavirus, which participate in RNA package and virus particle release. In this study, we expressed the N protein of SARS-CoV-2 and characterized its biochemical properties. Stati …
The nucleocapsid (N) protein is an important antigen for coronavirus, which participate in RNA package and virus particle rele …
2,692 results