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Year Number of Results
1959 1
1960 2
1962 2
1963 8
1964 22
1965 40
1966 49
1967 84
1968 106
1969 104
1970 135
1971 123
1972 131
1973 160
1974 144
1975 156
1976 172
1977 193
1978 170
1979 191
1980 237
1981 233
1982 266
1983 290
1984 367
1985 432
1986 426
1987 407
1988 425
1989 460
1990 502
1991 408
1992 484
1993 594
1994 565
1995 570
1996 584
1997 603
1998 727
1999 738
2000 886
2001 953
2002 939
2003 1003
2004 1076
2005 1105
2006 1112
2007 1109
2008 1048
2009 993
2010 1044
2011 1050
2012 1006
2013 1081
2014 1051
2015 991
2016 913
2017 847
2018 842
2019 761
2020 730
2021 693
2022 638
2023 572
2024 450
2025 32

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31,891 results

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Page 1
Selective estrogen receptor modulators (SERMs) and selective estrogen receptor degraders (SERDs) in cancer treatment.
Patel HK, Bihani T. Patel HK, et al. Pharmacol Ther. 2018 Jun;186:1-24. doi: 10.1016/j.pharmthera.2017.12.012. Epub 2017 Dec 28. Pharmacol Ther. 2018. PMID: 29289555 Free article. Review.
Breast cancer is the most frequently diagnosed cancer in women, with estrogen receptor positive (ER+) breast cancer making up approximately 75% of all breast cancers diagnosed. Given the dependence on active ER signaling in these tumors, the predominant treatment st …
Breast cancer is the most frequently diagnosed cancer in women, with estrogen receptor positive (ER+) breast cancer making up …
Estrogens and SERMS as adjunctive treatments for schizophrenia.
Kulkarni J, Butler S, Riecher-Rössler A. Kulkarni J, et al. Front Neuroendocrinol. 2019 Apr;53:100743. doi: 10.1016/j.yfrne.2019.03.002. Epub 2019 Mar 25. Front Neuroendocrinol. 2019. PMID: 30922675 Review.
More than thirty years have passed since sex and gender differences were noted in the age of onset, course and outcomes for schizophrenia. The 'estrogen hypothesis" was coined in the 1990's to describe neuroprotective effects of estrogen. Intervention studies in sch …
More than thirty years have passed since sex and gender differences were noted in the age of onset, course and outcomes for schizophrenia. T …
Selective Estrogen Receptor Modulators (SERMs): Mechanistic Insights Against Microbial Infections.
Garg A, Singh B, Sharma R, Singh A, Kumar A. Garg A, et al. Curr Mol Med. 2020;20(2):102-115. doi: 10.2174/1566524019666191014112133. Curr Mol Med. 2020. PMID: 31622201 Review.
A total of 101 studies have been published from 1997 -2018 regarding SERMs and microbial infections. RESULTS: On the basis of inclusion and exclusion criteria, 25 studies have been included for the analysis of level of evidence regarding antimicrobial effects of SERMs …
A total of 101 studies have been published from 1997 -2018 regarding SERMs and microbial infections. RESULTS: On the basis of inclusi …
Selective estrogen receptor modulators (SERMS): keys to understanding their function.
Liu JH. Liu JH. Menopause. 2020 Oct;27(10):1171-1176. doi: 10.1097/GME.0000000000001585. Menopause. 2020. PMID: 32576800 Review.
Selective estrogen receptor modulators (SERMs) are an increasingly important therapeutic modality that are used by clinicians on a daily basis. Unfortunately, clinicians have a limited understanding regarding the underlying mechanism(s) of how …
Selective estrogen receptor modulators (SERMs) are an increasingly important therapeutic modality that ar …
SERMs: current status and future trends.
Morello KC, Wurz GT, DeGregorio MW. Morello KC, et al. Crit Rev Oncol Hematol. 2002 Jul;43(1):63-76. doi: 10.1016/s1040-8428(02)00022-7. Crit Rev Oncol Hematol. 2002. PMID: 12098608 Review.
Selective estrogen receptor modulators, or SERMs, are a class of compounds that can act as estrogen receptor (ER) agonists in some tissues while acting as ER antagonists in others. SERMs are being evaluated and used to treat …
Selective estrogen receptor modulators, or SERMs, are a class of compounds that can act as estrogen …
SERMs: progress and future perspectives.
Pickar JH, MacNeil T, Ohleth K. Pickar JH, et al. Maturitas. 2010 Oct;67(2):129-38. doi: 10.1016/j.maturitas.2010.05.009. Epub 2010 Jun 26. Maturitas. 2010. PMID: 20580502 Review.
Selective estrogen receptor modulators (SERMs) interact with estrogen receptors as agonists or antagonists depending on the target tissue. ...Because current therapies do not adequately treat menopausal symptoms, the search continues for …
Selective estrogen receptor modulators (SERMs) interact with estrogen receptors as agonists or ant …
SERMs and SERMs with estrogen for postmenopausal osteoporosis.
Bolognese MA. Bolognese MA. Rev Endocr Metab Disord. 2010 Dec;11(4):253-9. doi: 10.1007/s11154-010-9137-1. Rev Endocr Metab Disord. 2010. PMID: 20446043 Review.
Therefore, other agents are under investigation. SERMs are a diverse group of agents that bind to the estrogen receptor and each SERM appears to have a unique set of clinical responses, which are not always consistent with the typical responses seen with othe …
Therefore, other agents are under investigation. SERMs are a diverse group of agents that bind to the estrogen receptor …
Selective estrogen receptor modulators (SERMs): a review of clinical data.
Mirkin S, Pickar JH. Mirkin S, et al. Maturitas. 2015 Jan;80(1):52-7. doi: 10.1016/j.maturitas.2014.10.010. Epub 2014 Oct 23. Maturitas. 2015. PMID: 25466304 Review.
SERMs have a long regulatory approval history and have been studied for a variety of therapeutic indications. ...The effect of SERMs in the vagina also represents a major distinction among different SERMs. This review summarized key clinical finding of SER …
SERMs have a long regulatory approval history and have been studied for a variety of therapeutic indications. ...The effect of SER …
SERMs: meeting the promise of multifunctional medicines.
Jordan VC. Jordan VC. J Natl Cancer Inst. 2007 Mar 7;99(5):350-6. doi: 10.1093/jnci/djk062. J Natl Cancer Inst. 2007. PMID: 17341726 Review.
The successful development and clinical evaluation of the selective estrogen receptor modulators in the Study of Tamoxifen and Raloxifene trial provides an occasion to reflect on the milestone that has been achieved and the potential for further progre …
The successful development and clinical evaluation of the selective estrogen receptor modulators in the Study of …
An overview of current and emerging SERMs.
Komm BS, Mirkin S. Komm BS, et al. J Steroid Biochem Mol Biol. 2014 Sep;143:207-22. doi: 10.1016/j.jsbmb.2014.03.003. Epub 2014 Mar 22. J Steroid Biochem Mol Biol. 2014. PMID: 24667357 Review.
Selective estrogen receptor modulators (SERMs) are compounds that exhibit tissue-specific estrogen receptor (ER) agonist or antagonist activity, and are used for various indications, including treatment of breast cancer, osteoporos …
Selective estrogen receptor modulators (SERMs) are compounds that exhibit tissue-specific estrogen …
31,891 results
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