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Relationship Between Hypothyroidism, Risk of Small Intestinal Bacterial Overgrowth, and Duodenal Microbiome Alterations.
Wei M, Mehravar S, Leite G, Naji P, Barlow GM, Hosseini A, Rashid M, Sanchez M, Fajardo CM, Pimentel M, Mathur R. Wei M, et al. J Clin Endocrinol Metab. 2026 Feb 20;111(3):707-720. doi: 10.1210/clinem/dgaf495. J Clin Endocrinol Metab. 2026. PMID: 40908532 Free article.
However, these risks appeared to be mitigated both in HUE (RR = 0.33) and autoimmune thyroiditis (RR = 0.78) subjects taking levothyroxine. Analyzing the duodenal microbiome, genus Neisseria was part of the core microbiome in the hypothyroid group (Hypo+/SIBO …
However, these risks appeared to be mitigated both in HUE (RR = 0.33) and autoimmune thyroiditis (RR = 0.78) subjects taking levothyroxin …
Levothyroxine Sodium Oral Solution Normalizes Thyroid Function in a Patient with Hashimoto's Disease, Gastritis, Diabetic Gastroparesis, and Small Intestinal Bacterial Overgrowth (SIBO).
Bohinc Henderson B. Bohinc Henderson B. Int Med Case Rep J. 2021 Sep 16;14:627-632. doi: 10.2147/IMCRJ.S326481. eCollection 2021. Int Med Case Rep J. 2021. PMID: 34557042 Free PMC article.
BACKGROUND: Levothyroxine (L-T4) is used as a standard-of-care treatment in patients with hypothyroidism. ...She was subsequently diagnosed with gastroparesis and small intestinal bacterial overgrowth (SIBO). Because of further worsening of her GI symptoms an …
BACKGROUND: Levothyroxine (L-T4) is used as a standard-of-care treatment in patients with hypothyroidism. ...She was subsequen …
Evaluation of probiotics in the treatment of hypothyroidism in early pregnancy combined with small intestinal bacterial overgrowth.
Zhang M, Xu Y, Sun Z, Ban Y, Zhai S, Wang W, Wang M, You J, Chen D, Zhu S, Guo H. Zhang M, et al. Food Sci Nutr. 2024 Jan 22;12(4):2671-2678. doi: 10.1002/fsn3.3948. eCollection 2024 Apr. Food Sci Nutr. 2024. PMID: 38628213 Free PMC article.
The aim of this study was to investigate the association between hypothyroidism in early pregnancy and small intestinal bacterial overgrowth (SIBO) and the effect of probiotics. ...Hypothyroidism in early pregnancy is associated with SIBO, and probioti …
The aim of this study was to investigate the association between hypothyroidism in early pregnancy and small intestinal bacterial ove …
Efficacy evaluation of probiotics combined with prebiotics in patients with clinical hypothyroidism complicated with small intestinal bacterial overgrowth during the second trimester of pregnancy.
Hao Y, Xu Y, Ban Y, Li J, Wu B, Ouyang Q, Sun Z, Zhang M, Cai Y, Wang M, Wang W. Hao Y, et al. Front Cell Infect Microbiol. 2022 Oct 6;12:983027. doi: 10.3389/fcimb.2022.983027. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36275023 Free PMC article.
The positive rate of intestinal bacterial overgrowth (SIBO), gastrointestinal symptoms, thyroid function and inflammatory factors were compared between the two groups by chi-square test and two independent sample t-test. (2) SIBO-positive patients in the clinical …
The positive rate of intestinal bacterial overgrowth (SIBO), gastrointestinal symptoms, thyroid function and inflammatory factors wer …
Liquid Thyroxine Improves Outcomes in Hypothyroid Patients With Small Intestinal Bacterial Overgrowth and Irritable Bowel Syndrome.
Henderson BB, Smith SP, Mengelkamp ME, Rhymer EK, Gray KN, Jackson AG, Henry SF, Chuang S, Stavrakas EH, Blair OM, Heaps M. Henderson BB, et al. Endocr Pract. 2024 Jun;30(6):505-512. doi: 10.1016/j.eprac.2024.03.005. Epub 2024 Mar 13. Endocr Pract. 2024. PMID: 38490469 Free article.
OBJECTIVE: Malabsorption of levothyroxine (LT4) is often seen in patients with hypothyroidism and gastrointestinal (GI) conditions. ...CONCLUSION: Small intestinal bacterial overgrowth (SIBO) is common in patients with hypothyroidism and IBS. Among …
OBJECTIVE: Malabsorption of levothyroxine (LT4) is often seen in patients with hypothyroidism and gastrointestinal (GI) condit …
Levothyroxine therapy and impaired clearance are the strongest contributors to small intestinal bacterial overgrowth: Results of a retrospective cohort study.
Brechmann T, Sperlbaum A, Schmiegel W. Brechmann T, et al. World J Gastroenterol. 2017 Feb 7;23(5):842-852. doi: 10.3748/wjg.v23.i5.842. World J Gastroenterol. 2017. PMID: 28223728 Free PMC article.
Impairment of the gastric acid barrier (gastrectomy, odds ratio: OR = 3.5, PPI therapy OR = 1.4), impairment of intestinal clearance (any resecting gastric surgery OR = 2.6, any colonic resection OR = 1.9, stenosis OR = 3.4, gastroparesis OR = 3.4, neuropathy 2.2), immunological …
Impairment of the gastric acid barrier (gastrectomy, odds ratio: OR = 3.5, PPI therapy OR = 1.4), impairment of intestinal clearance (any re …