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Page 1
Intestinal Involvement in Systemic Sclerosis: A Clinical Review.
Sakkas LI, Simopoulou T, Daoussis D, Liossis SN, Potamianos S. Sakkas LI, et al. Dig Dis Sci. 2018 Apr;63(4):834-844. doi: 10.1007/s10620-018-4977-8. Epub 2018 Feb 21. Dig Dis Sci. 2018. PMID: 29464583 Review.
Systemic sclerosis (SSc) is a chronic systemic disease characterized by microvasculopathy, autoantibodies, and extensive fibrosis. ...Assessment of intestinal involvement includes screening for small intestine hypomotility, malnutrition, SIBO, and anor …
Systemic sclerosis (SSc) is a chronic systemic disease characterized by microvasculopathy, autoantibodies, and extensiv …
Fecal calprotectin in systemic sclerosis and review of the literature.
Marie I, Leroi AM, Menard JF, Levesque H, Quillard M, Ducrotte P. Marie I, et al. Autoimmun Rev. 2015 Jun;14(6):547-54. doi: 10.1016/j.autrev.2015.01.018. Epub 2015 Feb 4. Autoimmun Rev. 2015. PMID: 25661980 Review.
Thus, this prospective study aimed to: 1) determine the prevalence of increased fecal calprotectin (FC) levels in unselected patients with systemic sclerosis (SSc); 2) make prediction about which SSc patients exhibit increased levels of FC; and 3) evaluate the corre …
Thus, this prospective study aimed to: 1) determine the prevalence of increased fecal calprotectin (FC) levels in unselected patients with …
Small intestinal bacterial overgrowth in systemic sclerosis: a review of the literature.
Polkowska-Pruszyńska B, Gerkowicz A, Szczepanik-Kułak P, Krasowska D. Polkowska-Pruszyńska B, et al. Arch Dermatol Res. 2019 Jan;311(1):1-8. doi: 10.1007/s00403-018-1874-0. Epub 2018 Oct 31. Arch Dermatol Res. 2019. PMID: 30382339 Free PMC article.
Systemic sclerosis (SSc) is a chronic, connective tissue disease with an autoimmune pattern characterized by inflammation, fibrosis and microcirculation changes leading to internal organs malfunctions. ...The study analysis showed an increased presence of SIBO …
Systemic sclerosis (SSc) is a chronic, connective tissue disease with an autoimmune pattern characterized by inflammation, fib …
Small Intestinal Bacterial Overgrowth Complicating Gastrointestinal Manifestations of Systemic Sclerosis: A Systematic Review and Meta-analysis.
Shah A, Pakeerathan V, Jones MP, Kashyap PC, Virgo K, Fairlie T, Morrison M, Ghoshal UC, Holtmann GJ. Shah A, et al. J Neurogastroenterol Motil. 2023 Apr 30;29(2):132-144. doi: 10.5056/jnm22168. J Neurogastroenterol Motil. 2023. PMID: 37019859 Free PMC article.
BACKGROUND/AIMS: Systemic sclerosis (SSc) often is complicated by small intestinal bacterial overgrowth (SIBO). A systematic review and meta-analysis thus examined the prevalence of SIBO in SSc (SSc-subtypes), identify risk factors for SIBO in S …
BACKGROUND/AIMS: Systemic sclerosis (SSc) often is complicated by small intestinal bacterial overgrowth (SIBO). A syste …
Prevalence and predictors of small intestinal bacterial overgrowth in systemic sclerosis: a systematic review and meta-analysis.
Feng X, Li XQ, Jiang Z. Feng X, et al. Clin Rheumatol. 2021 Aug;40(8):3039-3051. doi: 10.1007/s10067-020-05549-8. Epub 2021 Jan 11. Clin Rheumatol. 2021. PMID: 33426631
The reported prevalence of small intestinal bacterial overgrowth (SIBO) among patients with systemic sclerosis (SSc) is highly variable. We conducted this systematic review and meta-analysis to estimate the prevalence and identify predictors of SIBO in …
The reported prevalence of small intestinal bacterial overgrowth (SIBO) among patients with systemic sclerosis (SSc) is …
Calprotectin, an available prognostic biomarker in systemic sclerosis: a systematic review.
Ebrahimi B, Nazarinia M, Molayem M. Ebrahimi B, et al. Clin Rheumatol. 2021 May;40(5):1709-1715. doi: 10.1007/s10067-020-05446-0. Epub 2020 Oct 12. Clin Rheumatol. 2021. PMID: 33044726
BACKGROUND: Finding easier and less invasive biologic biomarker in the clinical specimen of systemic sclerosis (SSc) patients can be effective in diagnosing and treating SSc-associated multisystem diseases. ...CONCLUSION: The best source of Calprotectin was fecal Ca …
BACKGROUND: Finding easier and less invasive biologic biomarker in the clinical specimen of systemic sclerosis (SSc) patients …
Treatment of small intestinal bacterial overgrowth in systemic sclerosis: a systematic review.
Pittman N, Rawn SM, Wang M, Masetto A, Beattie KA, Larché M. Pittman N, et al. Rheumatology (Oxford). 2018 Oct 1;57(10):1802-1811. doi: 10.1093/rheumatology/key175. Rheumatology (Oxford). 2018. PMID: 29982822
Recent systematic reviews have reported efficacy of treatments for SIBO, but these are not specific to patients with SSc. We conducted a systematic review of the evidence for all possible SIBO treatments in the SSc population. ...Treatment outcomes included symptoma …
Recent systematic reviews have reported efficacy of treatments for SIBO, but these are not specific to patients with SSc. We conducte …
Nutritional Status and Dietary Challenges in Patients with Systemic Sclerosis: A Comprehensive Review.
Pardali EC, Gkouvi A, Grammatikopoulou MG, Mitropoulos A, Cholevas C, Poulimeneas D, Klonizakis M. Pardali EC, et al. Nutrients. 2025 Oct 1;17(19):3144. doi: 10.3390/nu17193144. Nutrients. 2025. PMID: 41097221 Free PMC article. Review.
The gastrointestinal (GI) tract is seriously affected by systemic sclerosis (SSc), due to fibrosis and persistent inflammation. Patients with GI involvement frequently exhibit poor nutritional status, which affects disease burden and quality of life. ...Symptomatolo …
The gastrointestinal (GI) tract is seriously affected by systemic sclerosis (SSc), due to fibrosis and persistent inflammation …
A Phenome-Wide Association Study of Drugs and Comorbidities Associated With Gastrointestinal Dysfunction in Systemic Sclerosis.
Maclean RH, Ahmed F, Ong VH, Murray CD, Denton CP. Maclean RH, et al. J Rheumatol. 2023 Jul;50(7):907-915. doi: 10.3899/jrheum.220990. Epub 2023 Feb 15. J Rheumatol. 2023. PMID: 36792109
OBJECTIVE: To explore the causes of and contributors to gastrointestinal (GI) dysfunction in systemic sclerosis (SSc) in a phenome-wide association study (PheWAS), using real-world clinical records data. ...A PheWAS model was used to explore links between 6 importan …
OBJECTIVE: To explore the causes of and contributors to gastrointestinal (GI) dysfunction in systemic sclerosis (SSc) in a phe …
Effectiveness of Saccharomyces boulardii and Metronidazole for Small Intestinal Bacterial Overgrowth in Systemic Sclerosis.
García-Collinot G, Madrigal-Santillán EO, Martínez-Bencomo MA, Carranza-Muleiro RA, Jara LJ, Vera-Lastra O, Montes-Cortes DH, Medina G, Cruz-Domínguez MP. García-Collinot G, et al. Dig Dis Sci. 2020 Apr;65(4):1134-1143. doi: 10.1007/s10620-019-05830-0. Epub 2019 Sep 23. Dig Dis Sci. 2020. PMID: 31549334 Clinical Trial.
BACKGROUND: Small intestinal bacterial overgrowth (SIBO) affects up to 60% of patients with systemic sclerosis (SSc), and it improves with antibiotics. ...AIMS: To evaluate the efficacy and safety of Saccharomyces boulardii (SB) versus metronidazole (M) versu …
BACKGROUND: Small intestinal bacterial overgrowth (SIBO) affects up to 60% of patients with systemic sclerosis (SSc), a …
24 results