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2014 4
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Page 1
Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems.
Karimi M, Ghasemi A, Sahandi Zangabad P, Rahighi R, Moosavi Basri SM, Mirshekari H, Amiri M, Shafaei Pishabad Z, Aslani A, Bozorgomid M, Ghosh D, Beyzavi A, Vaseghi A, Aref AR, Haghani L, Bahrami S, Hamblin MR. Karimi M, et al. Chem Soc Rev. 2016 Mar 7;45(5):1457-501. doi: 10.1039/c5cs00798d. Chem Soc Rev. 2016. PMID: 26776487 Free PMC article. Review.
Various differences between the extracellular and intracellular environments of cancerous and normal cells and the particular characteristics of tumors such as physicochemical properties, neovasculature, elasticity, surface electrical charge, and pH have motivated the design and …
Various differences between the extracellular and intracellular environments of cancerous and normal cells and the particular characteristic …
Fluorescent Polymers Conspectus.
Ahumada G, Borkowska M. Ahumada G, et al. Polymers (Basel). 2022 Mar 11;14(6):1118. doi: 10.3390/polym14061118. Polymers (Basel). 2022. PMID: 35335449 Free PMC article. Review.
The Nobel Prizes awarded in 2008 and 2010 for research on the development of green fluorescent proteins and super-resolved fluorescence imaging are proof of this (2014). Fluorescent probes, smart polymer machines, fluorescent chemosensors, fluorescence molecular thermomete …
The Nobel Prizes awarded in 2008 and 2010 for research on the development of green fluorescent proteins and super-resolved fluorescence imag …
Next-generation contact lenses: Towards bioresponsive drug delivery and smart technologies in ocular therapeutics.
Chaudhari P, Ghate VM, Lewis SA. Chaudhari P, et al. Eur J Pharm Biopharm. 2021 Apr;161:80-99. doi: 10.1016/j.ejpb.2021.02.007. Epub 2021 Feb 16. Eur J Pharm Biopharm. 2021. PMID: 33607239 Review.
In contrast to the conventional ocular formulations, contact lenses are well known for their diverse applications ranging from bio-sensing, prevention of myopia, cosmetics, and drug delivery. With a tremendous change in the lifestyle, contact lenses for therapeutic …
In contrast to the conventional ocular formulations, contact lenses are well known for their diverse applications ranging from bio-sensing, …
4D Printing of Hydrogels: Innovation in Material Design and Emerging Smart Systems for Drug Delivery.
Tran TS, Balu R, Mettu S, Roy Choudhury N, Dutta NK. Tran TS, et al. Pharmaceuticals (Basel). 2022 Oct 19;15(10):1282. doi: 10.3390/ph15101282. Pharmaceuticals (Basel). 2022. PMID: 36297394 Free PMC article. Review.
On the other hand, the expeditious development of 3D printing technologies has revolutionized the fabrication of hydrogel systems for biomedical applications. By combining these two aspects, 4D printing (i.e., 3D printing of smart hydrogels) has emerged as a new pro …
On the other hand, the expeditious development of 3D printing technologies has revolutionized the fabrication of hydrogel systems for …
Promising Drug Delivery Approaches to Treat Microbial Infections in the Vagina: A Recent Update.
Pandey M, Choudhury H, Abdul-Aziz A, Bhattamisra SK, Gorain B, Carine T, Wee Toong T, Yi NJ, Win Yi L. Pandey M, et al. Polymers (Basel). 2020 Dec 23;13(1):26. doi: 10.3390/polym13010026. Polymers (Basel). 2020. PMID: 33374756 Free PMC article. Review.
The lack of optimal prevention and treatment approaches have contributed to the unacceptably high rate of recurrence for vaginal diseases. To combat these limitations, several novel approaches including nano-systems, mucoadhesive polymeric systems, and sti …
The lack of optimal prevention and treatment approaches have contributed to the unacceptably high rate of recurrence for vaginal diseases. T …
A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer.
Huang K, Liang Q, Zhou Y, Jiang LL, Gu WM, Luo MY, Tang YB, Wang Y, Lu W, Huang M, Zhang SZ, Zhuang GL, Dai Q, Shen QC, Zhang J, Lei HM, Zhu L, Ye DY, Chen HZ, Zhou L, Shen Y. Huang K, et al. Cell Metab. 2019 Dec 3;30(6):1107-1119.e8. doi: 10.1016/j.cmet.2019.09.014. Epub 2019 Oct 10. Cell Metab. 2019. PMID: 31607564 Free article.
Allosteric regulation is considered to be an innovative strategy to discover a highly selective and potent inhibitor targeting PGAM1. Here, we identified a novel PGAM1 allosteric inhibitor, HKB99, via structure-based optimization. HKB99 acted to allosterically block …
Allosteric regulation is considered to be an innovative strategy to discover a highly selective and potent inhibitor targeting PGAM1. …
Polymer based Gels: Recent and Future Applications in Drug Delivery Field.
Siafaka PI, Gündoğdu EA, Cağlar ES, Özgenç E, Gonzalez-Alvarez M, Gonzalez-Alvarez I, Okur NÜ. Siafaka PI, et al. Curr Drug Deliv. 2023;20(9):1288-1313. doi: 10.2174/1567201819666220907124040. Curr Drug Deliv. 2023. PMID: 36082850 Review.
BACKGROUND: Currently, there is ongoing research in the pharmaceutical technology field to develop innovative drug delivery systems with improved therapeutic efficacy. OBJECTIVES: Although there is a high need for new drug molecules, most scient …
BACKGROUND: Currently, there is ongoing research in the pharmaceutical technology field to develop innovative drug delivery …
Highly efficient drug delivery systems based on functional supramolecular polymers: In vitro evaluation.
Cheng CC, Chang FC, Kao WY, Hwang SM, Liao LC, Chang YJ, Liang MC, Chen JK, Lee DJ. Cheng CC, et al. Acta Biomater. 2016 Mar;33:194-202. doi: 10.1016/j.actbio.2016.01.018. Epub 2016 Jan 18. Acta Biomater. 2016. PMID: 26796210
In this study, a practical approach to living polymerization of functionalized thermoresponsive monomers enabled the incorporation of self-constituted multiple hydrogen bonded groups into micelles that have potential as supramolecular drug-delivery systems. P …
In this study, a practical approach to living polymerization of functionalized thermoresponsive monomers enabled the incorporation of self-c …
Doxorubicin-loaded composite nanogels for cancer treatment.
Mohammadi M, Arabi L, Alibolandi M. Mohammadi M, et al. J Control Release. 2020 Dec 10;328:171-191. doi: 10.1016/j.jconrel.2020.08.033. Epub 2020 Aug 28. J Control Release. 2020. PMID: 32866591 Review.
Since a nanogel composite device transport encapsulated drugs to the site of action and release them in a desirable time-frame, it could provide higher therapeutic effect. By implementation of different polymers, polymer/inorganic NPs and various crosslinking chemistry, it …
Since a nanogel composite device transport encapsulated drugs to the site of action and release them in a desirable time-frame, it could pro …
Recent Advances in Gelatin-Based Nanomedicine for Targeted Delivery of Anti-Cancer Drugs.
Raza F, Siyu L, Zafar H, Kamal Z, Zheng B, Su J, Qiu M. Raza F, et al. Curr Pharm Des. 2022;28(5):380-394. doi: 10.2174/1381612827666211102100118. Curr Pharm Des. 2022. PMID: 34727851 Review.
Nanoparticles based on natural polymers are utilized for the development of a wide range of drug delivery systems (DDS) in the current era. ...In addition, various cross-linkers to stabilized nanocarriers and stimuli base gelatin nanoparticles a …
Nanoparticles based on natural polymers are utilized for the development of a wide range of drug delivery systems …
61 results