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Red and orange flags for secondary headaches in clinical practice: SNNOOP10 list.
Do TP, Remmers A, Schytz HW, Schankin C, Nelson SE, Obermann M, Hansen JM, Sinclair AJ, Gantenbein AR, Schoonman GG. Do TP, et al. Neurology. 2019 Jan 15;92(3):134-144. doi: 10.1212/WNL.0000000000006697. Epub 2018 Dec 26. Neurology. 2019. PMID: 30587518 Free PMC article. Review.
A minority of headache patients have a secondary headache disorder. The medical literature presents and promotes red flags to increase the likelihood of identifying a secondary etiology. In this review, we aim to discuss the incidence and …
A minority of headache patients have a secondary headache disorder. The medical literature presents and promotes red …
Acute Headache in Adults: A Diagnostic Approach.
Viera AJ, Antono B. Viera AJ, et al. Am Fam Physician. 2022 Sep;106(3):260-268. Am Fam Physician. 2022. PMID: 36126007 Free article.
Evaluating acute headaches using a systematic framework such as the SNNOOP10 mnemonic can help detect life-threatening secondary causes of headaches. ...For less urgent cases, magnetic resonance imaging of the brain is preferred for evaluating heada …
Evaluating acute headaches using a systematic framework such as the SNNOOP10 mnemonic can help detect life-threatening seco …
Predictive performance of the common red flags in emergency department headache patients: a HEAD and HEAD-Colombia study.
Chu K, Kelly AM, Kuan WS, Kinnear FB, Keijzers G, Horner D, Laribi S, Cardozo A, Karamercan MA, Klim S, Wijeratne T, Kamona S, Graham CA, Body R, Roberts T; HEAD and HEAD-Colombia study groups. Chu K, et al. Emerg Med J. 2024 May 28;41(6):368-375. doi: 10.1136/emermed-2023-213461. Emerg Med J. 2024. PMID: 38658053
OBJECTIVES: Only a small proportion of patients presenting to an ED with headache have a serious cause. The SNNOOP10 criteria, which incorporates red and orange flags for serious causes, has been proposed but not well studied. ...METHODS: Secondary …
OBJECTIVES: Only a small proportion of patients presenting to an ED with headache have a serious cause. The SNNOOP10 criteria, …
Sensitivity of the SNNOOP10 list in the high-risk secondary headache detection.
García-Azorín D, Abelaira-Freire J, González-García N, Rodriguez-Adrada E, Schytz HW, Barloese M, Guerrero ÁL, Porta-Etessam J, Martín-Sánchez FJ. García-Azorín D, et al. Cephalalgia. 2022 Dec;42(14):1521-1531. doi: 10.1177/03331024221120249. Epub 2022 Aug 24. Cephalalgia. 2022. PMID: 36003002
We identified 37 different diagnoses. Final diagnosis was a primary headache in 33%, secondary headache in 65% and cranial neuralgia in 2%. There were 46 patients that were considered as having high-risk headache. ...The area under the curve of the …
We identified 37 different diagnoses. Final diagnosis was a primary headache in 33%, secondary headache in 65% and cran …
Updates in the Diagnostic Approach of Headache.
Do TP, la Cour Karottki NF, Ashina M. Do TP, et al. Curr Pain Headache Rep. 2021 Dec 11;25(12):80. doi: 10.1007/s11916-021-00995-8. Curr Pain Headache Rep. 2021. PMID: 34894320 Review.
A special interest group under the International Headache Society recently synthesized information on red flags (information that indicates a secondary etiology) and green flags (information that indicates a primary etiology). A systematic diagn …
A special interest group under the International Headache Society recently synthesized information on red flags (inform …
"NAO E PRIMARIA": a Portuguese version of the SNNOOP10 mnemonic.
Leone DCMG, Segundo AFSM, Meira AT. Leone DCMG, et al. Arq Neuropsiquiatr. 2025 Dec;83(12):1-7. doi: 10.1055/s-0045-1813240. Epub 2025 Dec 8. Arq Neuropsiquiatr. 2025. PMID: 41360402 Free PMC article.
Secondary headaches arise from underlying medical conditions and are associated with significant morbidity and mortality. ...It consists of a structured checklist of 15 red flags, with validated sensitivity, specificity, and predictive values. However, …
Secondary headaches arise from underlying medical conditions and are associated with significant morbidity and mortality. ...I …