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SNPs in PPARG associate with type 2 diabetes and interact with physical activity.
Kilpeläinen TO, Lakka TA, Laaksonen DE, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Lindi V, Tuomilehto J, Uusitupa M, Laakso M. Kilpeläinen TO, et al. Med Sci Sports Exerc. 2008 Jan;40(1):25-33. doi: 10.1249/mss.0b013e318159d1cd. Med Sci Sports Exerc. 2008. PMID: 18091023 Clinical Trial.
PURPOSE: To study the associations of seven single-nucleotide polymorphisms (SNPs) in the peroxisome proliferator-activated receptor gamma (PPARG) gene with the conversion from impaired glucose tolerance (IGT) to type 2 diabetes …
PURPOSE: To study the associations of seven single-nucleotide polymorphisms (SNPs) in the peroxisome proliferato …
Genetic variation in the peroxisome proliferator-activated receptor (PPAR) and peroxisome proliferator-activated receptor gamma co-activator 1 (PGC1) gene families and type 2 diabetes.
Villegas R, Williams SM, Gao YT, Long J, Shi J, Cai H, Li H, Chen CC, Tai ES; AGEN-T2D Consortium; Hu F, Cai Q, Zheng W, Shu XO. Villegas R, et al. Ann Hum Genet. 2014 Jan;78(1):23-32. doi: 10.1111/ahg.12044. Ann Hum Genet. 2014. PMID: 24359475 Free PMC article.
We used a two-stage study design to evaluate whether variations in the peroxisome proliferator-activated receptors (PPAR) and the PPAR gamma co-activator 1 (PGC1) gene families (PPARA, PPARG, PPARD, PPARGC1A, and PPARGC1B) are associated with type 2 …
We used a two-stage study design to evaluate whether variations in the peroxisome proliferator-activated receptors (PPAR) and the PPAR gamma …