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Year Number of Results
2007 6
2008 5
2009 4
2010 5
2011 2
2012 3
2013 6
2014 6
2015 8
2016 11
2017 9
2018 4
2019 2
2020 1
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4 articles found by citation matching

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Alzheimer's disease risk genes and mechanisms of disease pathogenesis.
Karch CM, Goate AM. Karch CM, et al. Biol Psychiatry. 2015 Jan 1;77(1):43-51. doi: 10.1016/j.biopsych.2014.05.006. Epub 2014 May 17. Biol Psychiatry. 2015. PMID: 24951455 Free PMC article. Review.
We review the genetic risk factors for late-onset Alzheimer's disease (AD) and their role in AD pathogenesis. More recent advances in understanding of the human genome-technologic advances in methods to analyze millions of polymorphisms i …
We review the genetic risk factors for late-onset Alzheimer's disease (AD) and their role in AD pa …
SORL1 Is Associated with the Risk of Late-Onset Alzheimer's Disease: a Replication Study and Meta-Analyses.
Zhang CC, Wang HF, Tan MS, Wan Y, Zhang W, Zheng ZJ, Kong LL, Wang ZX, Tan L, Jiang T, Tan L, Yu JT. Zhang CC, et al. Mol Neurobiol. 2017 Apr;54(3):1725-1732. doi: 10.1007/s12035-016-9780-y. Epub 2016 Feb 13. Mol Neurobiol. 2017. PMID: 26873856
The sorting-related receptor gene (SORL1) has been defined as an interesting candidate gene for Alzheimer's disease (AD). Recently, one novel variant, rs11218343, within SORL1 was reported to be related to late-onset Alzheimer
The sorting-related receptor gene (SORL1) has been defined as an interesting candidate gene for Alzheimer's disease
Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease.
Villegas-Llerena C, Phillips A, Garcia-Reitboeck P, Hardy J, Pocock JM. Villegas-Llerena C, et al. Curr Opin Neurobiol. 2016 Feb;36:74-81. doi: 10.1016/j.conb.2015.10.004. Epub 2015 Oct 24. Curr Opin Neurobiol. 2016. PMID: 26517285 Review.
Neuroinflammation is a pathological hallmark of Alzheimer's disease (AD), and microglia, the brain's resident phagocyte, are pivotal for the immune response observed in AD. ...Recent Genome Wide Association Studies (GWAS) have identified more th …
Neuroinflammation is a pathological hallmark of Alzheimer's disease (AD), and microglia, the brain's resident ph …
Genomics of Alzheimer Disease: A Review.
Rosenberg RN, Lambracht-Washington D, Yu G, Xia W. Rosenberg RN, et al. JAMA Neurol. 2016 Jul 1;73(7):867-74. doi: 10.1001/jamaneurol.2016.0301. JAMA Neurol. 2016. PMID: 27135718 Free PMC article. Review.
IMPORTANCE: To provide a comprehensive review of knowledge of the genomics of Alzheimer disease (AD) and DNA amyloid β 42 (Aβ42) vaccination as a potential therapy. ...A number of common variants associated with late-onset AD have been id …
IMPORTANCE: To provide a comprehensive review of knowledge of the genomics of Alzheimer disease (AD) and DNA amyloid β 42 (Aβ4 …
SORL1 is genetically associated with neuropathologically characterized late-onset Alzheimer's disease.
Wen Y, Miyashita A, Kitamura N, Tsukie T, Saito Y, Hatsuta H, Murayama S, Kakita A, Takahashi H, Akatsu H, Yamamoto T, Kosaka K, Yamaguchi H, Akazawa K, Ihara Y, Kuwano R. Wen Y, et al. J Alzheimers Dis. 2013;35(2):387-94. doi: 10.3233/JAD-122395. J Alzheimers Dis. 2013. PMID: 23455993
SORL1 was shown to be genetically associated with late-onset Alzheimer's disease (LOAD) in a large-scale genome-wide association study (GWAS) involving clinically verified subjects. ...Case-control haplotype analysis
SORL1 was shown to be genetically associated with late-onset Alzheimer's disease (LO
SORL1 mutations in early- and late-onset Alzheimer disease.
Cuccaro ML, Carney RM, Zhang Y, Bohm C, Kunkle BW, Vardarajan BN, Whitehead PL, Cukier HN, Mayeux R, St George-Hyslop P, Pericak-Vance MA. Cuccaro ML, et al. Neurol Genet. 2016 Oct 26;2(6):e116. doi: 10.1212/NXG.0000000000000116. eCollection 2016 Dec. Neurol Genet. 2016. PMID: 27822510 Free PMC article.
OBJECTIVE: To characterize the clinical and molecular effect of mutations in the sortilin-related receptor (SORL1) gene. METHODS: We performed whole-exome sequencing in early-onset Alzheimer disease (EOAD) and late-onset Alzheimer
OBJECTIVE: To characterize the clinical and molecular effect of mutations in the sortilin-related receptor (SORL1) gene. METHODS: We …
SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
Miyashita A, Koike A, Jun G, Wang LS, Takahashi S, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, Higuchi S, Ikeuchi T, Nishizawa M, Suga M, Kawase Y, Akatsu H, Kosaka K, Yamamoto T, Imagawa M, Hamaguchi T, Yamada M, Morihara T, Takeda M, Takao T, Nakata K, Fujisawa Y, Sasaki K, Watanabe K, Nakashima K, Urakami K, Ooya T, Takahashi M, Yuzuriha T, Serikawa K, Yoshimoto S, Nakagawa R, Kim JW, Ki CS, Won HH, Na DL, Seo SW, Mook-Jung I; Alzheimer Disease Genetics Consortium, St George-Hyslop P, Mayeux R, Haines JL, Pericak-Vance MA, Yoshida M, Nishida N, Tokunaga K, Yamamoto K, Tsuji S, Kanazawa I, Ihara Y, Schellenberg GD, Farrer LA, Kuwano R. Miyashita A, et al. PLoS One. 2013;8(4):e58618. doi: 10.1371/journal.pone.0058618. Epub 2013 Apr 2. PLoS One. 2013. PMID: 23565137 Free PMC article.
To discover susceptibility genes of late-onset Alzheimer's disease (LOAD), we conducted a 3-stage genome-wide association study (GWAS) using three populations: Japanese from the Japanese Genetic Consortium for Alzheimer D
To discover susceptibility genes of late-onset Alzheimer's disease (LOAD), we conducted a 3-stage genome- …
Early Life Stress and Epigenetics in Late-onset Alzheimer's Dementia: A Systematic Review.
Lemche E. Lemche E. Curr Genomics. 2018 Nov;19(7):522-602. doi: 10.2174/1389202919666171229145156. Curr Genomics. 2018. PMID: 30386171 Free PMC article. Review.
Involvement of life stress in Late-Onset Alzheimer's Disease (LOAD) has been evinced in longitudinal cohort epidemiological studies, and endocrinologic evidence suggests involvements of catecholamine and corticosteroid systems in LOAD. ...In the …
Involvement of life stress in Late-Onset Alzheimer's Disease (LOAD) has been evinced in longitudinal coho …
SORL1 gene polymorphism association with late-onset Alzheimer's disease.
Feng X, Hou D, Deng Y, Li W, Tian M, Yu Z. Feng X, et al. Neurosci Lett. 2015 Jan 1;584:382-9. doi: 10.1016/j.neulet.2014.10.055. Epub 2014 Nov 4. Neurosci Lett. 2015. PMID: 25450149
We examined the relationship between loci polymorphisms (rs689021, rs3824966, and rs1784933) of the sortilin-related receptor 1 gene (SORL1) and late-onset Alzheimer's disease (LOAD) in the Chinese Han population of the Hunan Changsha reg …
We examined the relationship between loci polymorphisms (rs689021, rs3824966, and rs1784933) of the sortilin-related receptor 1 gene (SOR
A Rare Variant Nonparametric Linkage Method for Nuclear and Extended Pedigrees with Application to Late-Onset Alzheimer Disease via WGS Data.
Zhao L, He Z, Zhang D, Wang GT, Renton AE, Vardarajan BN, Nothnagel M, Goate AM, Mayeux R, Leal SM. Zhao L, et al. Am J Hum Genet. 2019 Oct 3;105(4):822-835. doi: 10.1016/j.ajhg.2019.09.006. Am J Hum Genet. 2019. PMID: 31585107 Free PMC article.
The RV-NPL was applied to analyze 107 late-onset Alzheimer disease (LOAD) pedigrees of Caribbean Hispanic and European ancestry with WGS data, and statistically significant linkage (LOD ≥ 3.8) was found with RVs in PSMF1 and PTPN21 which have been show …
The RV-NPL was applied to analyze 107 late-onset Alzheimer disease (LOAD) pedigrees of Caribbean Hispanic and Eu …
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