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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 6
2008 5
2009 4
2010 5
2011 2
2012 3
2013 6
2014 6
2015 8
2016 11
2017 9
2018 4
2019 2
2020 2
2021 5
2022 3
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68 results
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4 articles found by citation matching

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Alzheimer's disease risk genes and mechanisms of disease pathogenesis.
Karch CM, Goate AM. Karch CM, et al. Biol Psychiatry. 2015 Jan 1;77(1):43-51. doi: 10.1016/j.biopsych.2014.05.006. Epub 2014 May 17. Biol Psychiatry. 2015. PMID: 24951455 Free PMC article. Review.
We review the genetic risk factors for late-onset Alzheimer's disease (AD) and their role in AD pathogenesis. ...We review the relationship between these AD risk genes and the cellular and neuropathologic features of AD. Understanding the …
We review the genetic risk factors for late-onset Alzheimer's disease (AD) and their role in AD pa …
Early Life Stress and Epigenetics in Late-onset Alzheimer's Dementia: A Systematic Review.
Lemche E. Lemche E. Curr Genomics. 2018 Nov;19(7):522-602. doi: 10.2174/1389202919666171229145156. Curr Genomics. 2018. PMID: 30386171 Free PMC article. Review.
Involvement of life stress in Late-Onset Alzheimer's Disease (LOAD) has been evinced in longitudinal cohort epidemiological studies, and endocrinologic evidence suggests involvements of catecholamine and corticosteroid systems in LOAD. ...In the …
Involvement of life stress in Late-Onset Alzheimer's Disease (LOAD) has been evinced in longitudinal coho …
SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
Miyashita A, Koike A, Jun G, Wang LS, Takahashi S, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, Higuchi S, Ikeuchi T, Nishizawa M, Suga M, Kawase Y, Akatsu H, Kosaka K, Yamamoto T, Imagawa M, Hamaguchi T, Yamada M, Morihara T, Takeda M, Takao T, Nakata K, Fujisawa Y, Sasaki K, Watanabe K, Nakashima K, Urakami K, Ooya T, Takahashi M, Yuzuriha T, Serikawa K, Yoshimoto S, Nakagawa R, Kim JW, Ki CS, Won HH, Na DL, Seo SW, Mook-Jung I; Alzheimer Disease Genetics Consortium, St George-Hyslop P, Mayeux R, Haines JL, Pericak-Vance MA, Yoshida M, Nishida N, Tokunaga K, Yamamoto K, Tsuji S, Kanazawa I, Ihara Y, Schellenberg GD, Farrer LA, Kuwano R. Miyashita A, et al. PLoS One. 2013;8(4):e58618. doi: 10.1371/journal.pone.0058618. Epub 2013 Apr 2. PLoS One. 2013. PMID: 23565137 Free PMC article.
To discover susceptibility genes of late-onset Alzheimer's disease (LOAD), we conducted a 3-stage genome-wide association study (GWAS) using three populations: Japanese from the Japanese Genetic Consortium for Alzheimer D
To discover susceptibility genes of late-onset Alzheimer's disease (LOAD), we conducted a 3-stage genome- …
SORL1 is genetically associated with neuropathologically characterized late-onset Alzheimer's disease.
Wen Y, Miyashita A, Kitamura N, Tsukie T, Saito Y, Hatsuta H, Murayama S, Kakita A, Takahashi H, Akatsu H, Yamamoto T, Kosaka K, Yamaguchi H, Akazawa K, Ihara Y, Kuwano R. Wen Y, et al. J Alzheimers Dis. 2013;35(2):387-94. doi: 10.3233/JAD-122395. J Alzheimers Dis. 2013. PMID: 23455993
SORL1 was shown to be genetically associated with late-onset Alzheimer's disease (LOAD) in a large-scale genome-wide association study (GWAS) involving clinically verified subjects. ...Our replication study strongly s
SORL1 was shown to be genetically associated with late-onset Alzheimer's disease (LO
SORL1 mutations in early- and late-onset Alzheimer disease.
Cuccaro ML, Carney RM, Zhang Y, Bohm C, Kunkle BW, Vardarajan BN, Whitehead PL, Cukier HN, Mayeux R, St George-Hyslop P, Pericak-Vance MA. Cuccaro ML, et al. Neurol Genet. 2016 Oct 26;2(6):e116. doi: 10.1212/NXG.0000000000000116. eCollection 2016 Dec. Neurol Genet. 2016. PMID: 27822510 Free PMC article.
OBJECTIVE: To characterize the clinical and molecular effect of mutations in the sortilin-related receptor (SORL1) gene. METHODS: We performed whole-exome sequencing in early-onset Alzheimer disease (EOAD) and late-onset Alzheimer
OBJECTIVE: To characterize the clinical and molecular effect of mutations in the sortilin-related receptor (SORL1) gene. METHODS: We …
SORL1 Is Associated with the Risk of Late-Onset Alzheimer's Disease: a Replication Study and Meta-Analyses.
Zhang CC, Wang HF, Tan MS, Wan Y, Zhang W, Zheng ZJ, Kong LL, Wang ZX, Tan L, Jiang T, Tan L, Yu JT. Zhang CC, et al. Mol Neurobiol. 2017 Apr;54(3):1725-1732. doi: 10.1007/s12035-016-9780-y. Epub 2016 Feb 13. Mol Neurobiol. 2017. PMID: 26873856
The sorting-related receptor gene (SORL1) has been defined as an interesting candidate gene for Alzheimer's disease (AD). Recently, one novel variant, rs11218343, within SORL1 was reported to be related to late-onset Alzheimer
The sorting-related receptor gene (SORL1) has been defined as an interesting candidate gene for Alzheimer's disease
SORL1 is genetically associated with increased risk for late-onset Alzheimer disease in the Belgian population.
Bettens K, Brouwers N, Engelborghs S, De Deyn PP, Van Broeckhoven C, Sleegers K. Bettens K, et al. Hum Mutat. 2008 May;29(5):769-70. doi: 10.1002/humu.20725. Hum Mutat. 2008. PMID: 18407551
SORL1 has recently been identified as a major genetic contributor to increased risk for late-onset Alzheimer disease (AD). ...Two signals in distinct regions of the gene were shown to be mutually independent, supporting allelic heterogene
SORL1 has recently been identified as a major genetic contributor to increased risk for late-onset Alzheimer
SORL1 Variants Show Different Association with Early-Onset and Late-Onset Alzheimer's Disease Risk.
Liu G, Sun JY, Xu M, Yang XY, Sun BL. Liu G, et al. J Alzheimers Dis. 2017;58(4):1121-1128. doi: 10.3233/JAD-170005. J Alzheimers Dis. 2017. PMID: 28527213
A recent study sequenced the full coding region of SORL1 in 1,255 early-onset Alzheimer's disease (EOAD) cases and 1,938 control individuals, and investigated the contribution of genetic variability in SORL1 to EOAD risk in a Europ …
A recent study sequenced the full coding region of SORL1 in 1,255 early-onset Alzheimer's disease (EOAD) …
SORL1 gene polymorphism association with late-onset Alzheimer's disease.
Feng X, Hou D, Deng Y, Li W, Tian M, Yu Z. Feng X, et al. Neurosci Lett. 2015 Jan 1;584:382-9. doi: 10.1016/j.neulet.2014.10.055. Epub 2014 Nov 4. Neurosci Lett. 2015. PMID: 25450149
We examined the relationship between loci polymorphisms (rs689021, rs3824966, and rs1784933) of the sortilin-related receptor 1 gene (SORL1) and late-onset Alzheimer's disease (LOAD) in the Chinese Han population of the Hunan Changsha reg …
We examined the relationship between loci polymorphisms (rs689021, rs3824966, and rs1784933) of the sortilin-related receptor 1 gene (SOR
Genomics of Alzheimer's disease implicates the innate and adaptive immune systems.
Li Y, Laws SM, Miles LA, Wiley JS, Huang X, Masters CL, Gu BJ. Li Y, et al. Cell Mol Life Sci. 2021 Dec;78(23):7397-7426. doi: 10.1007/s00018-021-03986-5. Epub 2021 Oct 27. Cell Mol Life Sci. 2021. PMID: 34708251 Review.
Alzheimer's disease (AD) is a chronic neurodegenerative disease characterised by cognitive impairment, behavioural alteration, and functional decline. Over 130 AD-associated susceptibility loci have been identified by genome-wide association
Alzheimer's disease (AD) is a chronic neurodegenerative disease characterised by cognitive impairment, behaviour
68 results