Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2017 1
2019 1
2020 1
2021 1
2022 3
2023 2
2024 3
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

9 results

Results by year

Filters applied: . Clear all
Page 1
Upregulated miR-194-5p suppresses retinal microvascular endothelial cell dysfunction and mitigates the symptoms of hypertensive retinopathy in mice by targeting SOX17 and VEGF signaling.
Wan Q, Liu H, Xu Y, Zhang Q, Tao L. Wan Q, et al. Cell Cycle. 2023 Feb;22(3):331-346. doi: 10.1080/15384101.2022.2119514. Epub 2022 Oct 5. Cell Cycle. 2023. PMID: 36200131 Free PMC article.
In this study, the role and upstream mechanism of SRY-box transcription factor 17 (SOX17) in HR pathogenesis were investigated. METHODS: SOX17 and miR-194-5p levels in Angiotensin II (Ang II)-stimulated human retinal microvascular endothelial cells …
In this study, the role and upstream mechanism of SRY-box transcription factor 17 (SOX17) in HR pathogenesis were investigated. METHO …
Sox17 protects human brain microvascular endothelial cells from AngII-induced injury by regulating autophagy and apoptosis.
Wang Y, Fang M, Ren Q, Qi W, Bai X, Amin N, Zhang X, Li Z, Zhang L. Wang Y, et al. Mol Cell Biochem. 2024 Sep;479(9):2337-2350. doi: 10.1007/s11010-023-04838-5. Epub 2023 Sep 2. Mol Cell Biochem. 2024. PMID: 37659973 Free PMC article.
Hypertension is major IA risk factor that mediates endothelial cell damage. Sox17 is highly expressed in intracranial vascular endothelial cells, and GWAS studies indicate that its genetic alteration is one of the major genetic risk factors for …
Hypertension is major IA risk factor that mediates endothelial cell damage. Sox17 is highly expressed in intracranial v …
Single-cell transcriptomic profiling of lung endothelial cells identifies dynamic inflammatory and regenerative subpopulations.
Zhang L, Gao S, White Z, Dai Y, Malik AB, Rehman J. Zhang L, et al. JCI Insight. 2022 Jun 8;7(11):e158079. doi: 10.1172/jci.insight.158079. JCI Insight. 2022. PMID: 35511435 Free PMC article.
Studies have demonstrated the phenotypic heterogeneity of vascular endothelial cells (ECs) within a vascular bed; however, little is known about how distinct endothelial subpopulations in a particular organ respond to an inflammatory stimulus. ...After the pe …
Studies have demonstrated the phenotypic heterogeneity of vascular endothelial cells (ECs) within a vascular bed; however, lit …
Derivation, Expansion, Cryopreservation and Characterization of Brain Microvascular Endothelial Cells from Human Induced Pluripotent Stem Cells.
Pong S, Lizano P, Karmacharya R. Pong S, et al. J Vis Exp. 2020 Nov 19;(165). doi: 10.3791/61629. J Vis Exp. 2020. PMID: 33283783
Brain microvascular endothelial cells (BMECs) can be differentiated from human induced pluripotent stem cells (iPSCs) to develop ex vivo cellular models for studying blood-brain barrier (BBB) function. ...Successful derivation of BMECs is confirmed by …
Brain microvascular endothelial cells (BMECs) can be differentiated from human induced pluripotent stem cells (i …
SEMA3G regulates BMP9 inhibition of VEGF-mediated migration and network formation in pulmonary endothelial cells.
Mirza SL, Upton PD, Hodgson J, Gräf S, Morrell NW, Dunmore BJ. Mirza SL, et al. Vascul Pharmacol. 2024 Jun;155:107381. doi: 10.1016/j.vph.2024.107381. Epub 2024 May 23. Vascul Pharmacol. 2024. PMID: 38795838 Free article.
AIMS: Bone morphogenetic protein-9 (BMP9) is critical for bone morphogenetic protein receptor type-2 (BMPR2) signalling in pulmonary vascular endothelial cells. Furthermore, human genetics studies support the central role of disrupted BMPR2 mediated BMP9 signalling …
AIMS: Bone morphogenetic protein-9 (BMP9) is critical for bone morphogenetic protein receptor type-2 (BMPR2) signalling in pulmonary vascula …
Developmental regulation of barrier- and non-barrier blood vessels in the CNS.
Ben-Zvi A, Liebner S. Ben-Zvi A, et al. J Intern Med. 2022 Jul;292(1):31-46. doi: 10.1111/joim.13263. Epub 2021 Mar 4. J Intern Med. 2022. PMID: 33665890 Free article. Review.
In most vertebrates, the BBB is localized to microvascular endothelial cells that acquire barrier properties during angiogenesis of the neuroectoderm. ...In this review, we summarize the currently known cellular (neural precursor and endothelial cel …
In most vertebrates, the BBB is localized to microvascular endothelial cells that acquire barrier properties during ang …
Deubiquitinase UCHL1 promotes angiogenesis and blood-spinal cord barrier function recovery after spinal cord injury by stabilizing Sox17.
Wang J, Ji C, Ye W, Rong Y, Ge X, Wang Z, Tang P, Zhou Z, Luo Y, Cai W. Wang J, et al. Cell Mol Life Sci. 2024 Mar 13;81(1):137. doi: 10.1007/s00018-024-05186-3. Cell Mol Life Sci. 2024. PMID: 38478109 Free PMC article.
However, little is known about the regulation of deubiquitinated enzymes in endothelial cells and their effect on BSCB function after SCI. We observed that Sox17 is predominantly localized in endothelial cells and is significantly upregulated af …
However, little is known about the regulation of deubiquitinated enzymes in endothelial cells and their effect on BSCB functio …
Quantitative Proteomics Analysis of Ischemia/Reperfusion Injury-Modulated Proteins in Cardiac Microvascular Endothelial Cells and the Protective Role of Tongxinluo.
Li Q, Cui HH, Yang YJ, Li XD, Chen GH, Tian XQ, Jin C, Dong QT, Huang PS, Xu J. Li Q, et al. Cell Physiol Biochem. 2017;41(4):1503-1518. doi: 10.1159/000470806. Epub 2017 Mar 24. Cell Physiol Biochem. 2017. PMID: 28334711 Free article.
BACKGROUND: The protection of endothelial cells (ECs) against reperfusion injury has received little attention. In this study, we used Tandem Mass Tag (TMT) labeling proteomics to investigate the modulated proteins in an in vitro model of cardiac microvascular …
BACKGROUND: The protection of endothelial cells (ECs) against reperfusion injury has received little attention. In this study, …
Endocardium differentiation through Sox17 expression in endocardium precursor cells regulates heart development in mice.
Saba R, Kitajima K, Rainbow L, Engert S, Uemura M, Ishida H, Kokkinopoulos I, Shintani Y, Miyagawa S, Kanai Y, Kanai-Azuma M, Koopman P, Meno C, Kenny J, Lickert H, Saga Y, Suzuki K, Sawa Y, Yashiro K. Saba R, et al. Sci Rep. 2019 Aug 16;9(1):11953. doi: 10.1038/s41598-019-48321-y. Sci Rep. 2019. PMID: 31420575 Free PMC article.
We now show that Nkx2-5(+) cardiac progenitor cells (CPCs) that express the Sry-type HMG box gene Sox17 from embryonic day (E) 7.5 to E8.5 specifically differentiate into the endocardium in mouse embryos. ...On the other hand, Sox17 expression in the endocard …
We now show that Nkx2-5(+) cardiac progenitor cells (CPCs) that express the Sry-type HMG box gene Sox17 from embryonic day (E) …