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Expression of Sox1, Sox2 and Sox9 is maintained in adult human cerebellar cortex.
Alcock J, Lowe J, England T, Bath P, Sottile V. Alcock J, et al. Neurosci Lett. 2009 Jan 30;450(2):114-6. doi: 10.1016/j.neulet.2008.11.047. Epub 2008 Nov 27. Neurosci Lett. 2009. PMID: 19061938
Expression of Sox1, Sox2 and Sox9 was detected at the mRNA level in both foetal and adult cerebellum samples, suggesting that the maintenance of these markers in adult tissue is also observed in the human cerebellum. Expression of these markers was further co …
Expression of Sox1, Sox2 and Sox9 was detected at the mRNA level in both foetal and adult cerebellum samples, suggesting that …
Astrocytic abnormalities and global DNA methylation patterns in depression and suicide.
Nagy C, Suderman M, Yang J, Szyf M, Mechawar N, Ernst C, Turecki G. Nagy C, et al. Mol Psychiatry. 2015 Mar;20(3):320-8. doi: 10.1038/mp.2014.21. Epub 2014 Mar 25. Mol Psychiatry. 2015. PMID: 24662927 Free PMC article.
We first characterized prefrontal cortex samples from 121 individuals (76 who died during a depressive episode and 45 healthy controls) for the astrocytic markers GFAP, ALDH1L1, SOX9, GLUL, SCL1A3, GJA1 and GJB6. ...Cell-sorted fractions were investigated and demons …
We first characterized prefrontal cortex samples from 121 individuals (76 who died during a depressive episode and 45 healthy control …
Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness.
Bogeas A, Morvan-Dubois G, El-Habr EA, Lejeune FX, Defrance M, Narayanan A, Kuranda K, Burel-Vandenbos F, Sayd S, Delaunay V, Dubois LG, Parrinello H, Rialle S, Fabrega S, Idbaih A, Haiech J, Bièche I, Virolle T, Goodhardt M, Chneiweiss H, Junier MP. Bogeas A, et al. Acta Neuropathol. 2018 Feb;135(2):267-283. doi: 10.1007/s00401-017-1783-x. Epub 2017 Nov 17. Acta Neuropathol. 2018. PMID: 29149419 Free PMC article.
We found that ARNT2 knockdown decreased the expression of SOX9, POU3F2 and OLIG2, transcription factors implicated in glioblastoma cell tumorigenicity, and repressed glioblastoma stem-like cell tumorigenic properties in vivo. ...
We found that ARNT2 knockdown decreased the expression of SOX9, POU3F2 and OLIG2, transcription factors implicated in glioblastoma ce …
Epidermal growth factor preserves myelin and promotes astrogliosis after intraventricular hemorrhage.
Vinukonda G, Hu F, Mehdizadeh R, Dohare P, Kidwai A, Juneja A, Naran V, Kierstead M, Chawla R, Kayton R, Ballabh P. Vinukonda G, et al. Glia. 2016 Nov;64(11):1987-2004. doi: 10.1002/glia.23037. Epub 2016 Jul 29. Glia. 2016. PMID: 27472419 Free PMC article.
Here, we hypothesized that recombinant human (rh) EGF treatment would enhance oligodendrocyte precursor cell (OPC) maturation, myelination, and neurological recovery in preterm rabbits with IVH. ...We tested these hypotheses in a preterm rabbit model of IVH and evaluated a …
Here, we hypothesized that recombinant human (rh) EGF treatment would enhance oligodendrocyte precursor cell (OPC) maturation, myelin …
Progenitor Cells from Cartilage: Grade Specific Differences in Stem Cell Marker Expression.
Mazor M, Cesaro A, Ali M, Best TM, Lespessaille E, Toumi H. Mazor M, et al. Int J Mol Sci. 2017 Aug 12;18(8):1759. doi: 10.3390/ijms18081759. Int J Mol Sci. 2017. PMID: 28805694 Free PMC article.
Human osteoarthritic tibial plateaus were obtained from ten patients undergoing total knee replacement. Each sample had been classified into a mild or severe group according to OARSI scoring. ...Moreover, cells from the mild OA subjects showed significantly higher l
Human osteoarthritic tibial plateaus were obtained from ten patients undergoing total knee replacement. Each sample had been c
Supra- and infratentorial pediatric ependymomas differ significantly in NeuN, p75 and GFAP expression.
Hagel C, Treszl A, Fehlert J, Harder J, von Haxthausen F, Kern M, von Bueren AO, Kordes U. Hagel C, et al. J Neurooncol. 2013 Apr;112(2):191-7. doi: 10.1007/s11060-013-1062-1. Epub 2013 Jan 31. J Neurooncol. 2013. PMID: 23371454
Expression of high and low affinity neurotrophin receptors TrkA (NTRK1) and p75 (NGFR), pan-neuronal markers NeuN (RBFOX3) and synaptophysin, radial glial marker SOX9, adhesion molecules CD56 (NCAM) and CD44, junctional protein connexin 43 (GJA1), glial fibrillary a …
Expression of high and low affinity neurotrophin receptors TrkA (NTRK1) and p75 (NGFR), pan-neuronal markers NeuN (RBFOX3) and synapt …
Transforming growth factor-β1 may be a key mediator of the fibrogenic properties of neural cells in leprosy.
Petito RB, Amadeu TP, Pascarelli BM, Jardim MR, Vital RT, Antunes SL, Sarno EN. Petito RB, et al. J Neuropathol Exp Neurol. 2013 Apr;72(4):351-66. doi: 10.1097/NEN.0b013e31828bfc60. J Neuropathol Exp Neurol. 2013. PMID: 23481710
Mycobacterium leprae and TGF-β1 also induced increased type I collagen and fibronectin mRNA and secretion and augmented mRNA levels of SOX9 and ZEB1, which are involved in the epithelial-mesenchymal transition. ...Results of transcriptional studies of 3 leprosy nerves and …
Mycobacterium leprae and TGF-β1 also induced increased type I collagen and fibronectin mRNA and secretion and augmented mRNA levels of SO
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