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Page 1
Expression of Sox1, Sox2 and Sox9 is maintained in adult human cerebellar cortex.
Alcock J, Lowe J, England T, Bath P, Sottile V. Alcock J, et al. Neurosci Lett. 2009 Jan 30;450(2):114-6. doi: 10.1016/j.neulet.2008.11.047. Epub 2008 Nov 27. Neurosci Lett. 2009. PMID: 19061938
The present study establishes that expression of these marker genes is also found in the human cerebellum beyond the maturation phase. Expression of Sox1, Sox2 and Sox9 was detected at the mRNA level in both foetal and adult cerebellum samples, suggesting tha …
The present study establishes that expression of these marker genes is also found in the human cerebellum beyond the maturation phase …
SOX9 Expression Is Increased in Alzheimer's Disease (AD) and Is Associated With Disease Progression and APOE4 Genotype: A Computational Approach.
Alamoudi AA. Alamoudi AA. Cureus. 2023 Mar 14;15(3):e36129. doi: 10.7759/cureus.36129. eCollection 2023 Mar. Cureus. 2023. PMID: 37065298 Free PMC article.
Using human AD publicly available dataset, we aimed to analyze SOX9 expression and its relation to disease. ...The GSE48350 consisted of mRNA microarray data from 55 normal controls (173 samples) and 26 AD cases (81 samples) obtained, from four brain r …
Using human AD publicly available dataset, we aimed to analyze SOX9 expression and its relation to disease. ...The GSE48350 co …
Deconstructing Olfactory Epithelium Developmental Pathways in Olfactory Neuroblastoma.
Finlay JB, Abi Hachem R, Jang DW, Osazuwa-Peters N, Goldstein BJ. Finlay JB, et al. Cancer Res Commun. 2023 Jun 6;3(6):980-990. doi: 10.1158/2767-9764.CRC-23-0013. eCollection 2023 Jun. Cancer Res Commun. 2023. PMID: 37377616 Free PMC article.
We analyzed a total of 19 olfactory neuroblastoma samples with available bulk RNA-sequencing and survival data, along with 10 samples from normal olfactory epithelium. A bulk RNA-sequencing deconvolution model identified a significant increase in globose basal cell …
We analyzed a total of 19 olfactory neuroblastoma samples with available bulk RNA-sequencing and survival data, along with 10 samp
Epidermal growth factor preserves myelin and promotes astrogliosis after intraventricular hemorrhage.
Vinukonda G, Hu F, Mehdizadeh R, Dohare P, Kidwai A, Juneja A, Naran V, Kierstead M, Chawla R, Kayton R, Ballabh P. Vinukonda G, et al. Glia. 2016 Nov;64(11):1987-2004. doi: 10.1002/glia.23037. Epub 2016 Jul 29. Glia. 2016. PMID: 27472419 Free PMC article.
Epidermal growth factor (EGF) enhances myelination, astrogliosis, and neurologic recovery in animal models of white matter injury. Here, we hypothesized that recombinant human (rh) EGF treatment would enhance oligodendrocyte precursor cell (OPC) maturation, myelination, an …
Epidermal growth factor (EGF) enhances myelination, astrogliosis, and neurologic recovery in animal models of white matter injury. Here, we …
Progenitor Cells from Cartilage: Grade Specific Differences in Stem Cell Marker Expression.
Mazor M, Cesaro A, Ali M, Best TM, Lespessaille E, Toumi H. Mazor M, et al. Int J Mol Sci. 2017 Aug 12;18(8):1759. doi: 10.3390/ijms18081759. Int J Mol Sci. 2017. PMID: 28805694 Free PMC article.
Each sample had been classified into a mild or severe group according to OARSI scoring. Tissue was taken from each specimen and mRNA expression levels of CD105, CD166, Notch 1, Sox9, Acan and Col II A1 were measured at day 0 and day 14 (2 weeks in vitro). ...
Each sample had been classified into a mild or severe group according to OARSI scoring. Tissue was taken from each specimen and mRNA …
Astrocytic abnormalities and global DNA methylation patterns in depression and suicide.
Nagy C, Suderman M, Yang J, Szyf M, Mechawar N, Ernst C, Turecki G. Nagy C, et al. Mol Psychiatry. 2015 Mar;20(3):320-8. doi: 10.1038/mp.2014.21. Epub 2014 Mar 25. Mol Psychiatry. 2015. PMID: 24662927 Free PMC article.
Here we report a two-stage study investigating genome-wide DNA methylation associated with astrocytic markers in depressive psychopathology. We first characterized prefrontal cortex samples from 121 individuals (76 who died during a depressive episode and 45 healthy contro …
Here we report a two-stage study investigating genome-wide DNA methylation associated with astrocytic markers in depressive psychopathology. …
Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness.
Bogeas A, Morvan-Dubois G, El-Habr EA, Lejeune FX, Defrance M, Narayanan A, Kuranda K, Burel-Vandenbos F, Sayd S, Delaunay V, Dubois LG, Parrinello H, Rialle S, Fabrega S, Idbaih A, Haiech J, Bièche I, Virolle T, Goodhardt M, Chneiweiss H, Junier MP. Bogeas A, et al. Acta Neuropathol. 2018 Feb;135(2):267-283. doi: 10.1007/s00401-017-1783-x. Epub 2017 Nov 17. Acta Neuropathol. 2018. PMID: 29149419 Free PMC article.
Moreover, ARNT2 expression correlated with a tumorigenic molecular signature at both the tissue level within the tumor core and at the single cell level in the patients' tumors. We found that ARNT2 knockdown decreased the expression of SOX9, POU3F2 and OLIG2, transcription …
Moreover, ARNT2 expression correlated with a tumorigenic molecular signature at both the tissue level within the tumor core and at the singl …
Supra- and infratentorial pediatric ependymomas differ significantly in NeuN, p75 and GFAP expression.
Hagel C, Treszl A, Fehlert J, Harder J, von Haxthausen F, Kern M, von Bueren AO, Kordes U. Hagel C, et al. J Neurooncol. 2013 Apr;112(2):191-7. doi: 10.1007/s11060-013-1062-1. Epub 2013 Jan 31. J Neurooncol. 2013. PMID: 23371454
Recent studies revealed that some supratentorial ependymomas express neuronal antigens and that high expression of neurofilament protein light polypeptide (NEFL) correlates with better clinical outcome. ...Expression of high and low affinity neurotrophin receptors TrkA (NT …
Recent studies revealed that some supratentorial ependymomas express neuronal antigens and that high expression of neurofilament prot …
Transforming growth factor-β1 may be a key mediator of the fibrogenic properties of neural cells in leprosy.
Petito RB, Amadeu TP, Pascarelli BM, Jardim MR, Vital RT, Antunes SL, Sarno EN. Petito RB, et al. J Neuropathol Exp Neurol. 2013 Apr;72(4):351-66. doi: 10.1097/NEN.0b013e31828bfc60. J Neuropathol Exp Neurol. 2013. PMID: 23481710
Mycobacterium leprae and TGF-beta1 also induced increased type I collagen and fibronectin mRNA and secretion and augmented mRNA levels of SOX9 and ZEB1, which are involved in the epithelial-mesenchymal transition. ...Results of transcriptional studies of 3 leprosy nerves a …
Mycobacterium leprae and TGF-beta1 also induced increased type I collagen and fibronectin mRNA and secretion and augmented mRNA levels of …