Salmonella Typhimurium reprograms macrophage metabolism via T3SS effector SopE2 to promote intracellular replication and virulence.
Nat Commun. 2021 Feb 9;12(1):879. doi: 10.1038/s41467-021-21186-4.
Nat Commun. 2021.
PMID: 33563986
Free PMC article.
Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S. Typhimurium exhibit upregulated glycolysis and decreased serine synthesis, leading to accumulation of glycolytic intermedi …
Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infect …