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Year Number of Results
1992 1
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2002 8
2003 3
2004 2
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2008 12
2009 9
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253 results

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Page 1
LINC01094/SPI1/CCL7 Axis Promotes Macrophage Accumulation in Lung Adenocarcinoma and Tumor Cell Dissemination.
Wu Z, Bai X, Lu Z, Liu S, Jiang H. Wu Z, et al. J Immunol Res. 2022 Sep 9;2022:6450721. doi: 10.1155/2022/6450721. eCollection 2022. J Immunol Res. 2022. PMID: 36118415 Free PMC article.
METHODS: The expression profile of CCL7 in LUAD and its correlations with patient's prognosis and macrophage infiltration were predicted via bioinformatics systems. ...Upregulation of SPI1 restored the chemotactic migration and M2 polarization of macrophag …
METHODS: The expression profile of CCL7 in LUAD and its correlations with patient's prognosis and macrophage infiltration were …
SPI1-related protein inhibits cervical cancer cell progression and prevents macrophage cell migration.
Jin J, Du X, Zhou L, Yao D, Zou Q. Jin J, et al. J Obstet Gynaecol Res. 2022 Sep;48(9):2419-2430. doi: 10.1111/jog.15336. Epub 2022 Jun 30. J Obstet Gynaecol Res. 2022. PMID: 35770729
The mRNA and protein levels of genes were examined by RT-qPCR and western blot assays, respectively. The effect of SPIB on macrophage cells was tested by macrophage recruitment assay and bioinformatics analysis. ...Higher SPIB expression was associated with less M2 …
The mRNA and protein levels of genes were examined by RT-qPCR and western blot assays, respectively. The effect of SPIB on macrophage …
Salmonella Typhimurium reprograms macrophage metabolism via T3SS effector SopE2 to promote intracellular replication and virulence.
Jiang L, Wang P, Song X, Zhang H, Ma S, Wang J, Li W, Lv R, Liu X, Ma S, Yan J, Zhou H, Huang D, Cheng Z, Yang C, Feng L, Wang L. Jiang L, et al. Nat Commun. 2021 Feb 9;12(1):879. doi: 10.1038/s41467-021-21186-4. Nat Commun. 2021. PMID: 33563986 Free PMC article.
Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S. Typhimurium exhibit upregulated glycolysis and decreased serine synthesis, leading to accumulation of glycolytic intermedi …
Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infect …
TET2 regulates osteoclastogenesis by modulating autophagy in OVX-induced bone loss.
Yang C, Tao H, Zhang H, Xia Y, Bai J, Ge G, Li W, Zhang W, Xiao L, Xu Y, Wang Z, Gu Y, Yang H, Liu Y, Geng D. Yang C, et al. Autophagy. 2022 Dec;18(12):2817-2829. doi: 10.1080/15548627.2022.2048432. Epub 2022 Mar 24. Autophagy. 2022. PMID: 35255774 Free PMC article.
In summary, our findings provide evidence that TET2 promotes osteoclast differentiation by inhibiting BCL2 expression and positively regulating BECN1-dependent autophagy.Abbreviations: ACP5/TRAP: acid phosphatase 5, tartrate resistant; ATP6V0D2: ATPase, H+ transporting, lysosomal …
In summary, our findings provide evidence that TET2 promotes osteoclast differentiation by inhibiting BCL2 expression and positively regulat …
Regulation of the MIR155 host gene in physiological and pathological processes.
Elton TS, Selemon H, Elton SM, Parinandi NL. Elton TS, et al. Gene. 2013 Dec 10;532(1):1-12. doi: 10.1016/j.gene.2012.12.009. Epub 2012 Dec 14. Gene. 2013. PMID: 23246696 Review.
MiR-155-5p is highly expressed in both activated B- and T-cells and in monocytes/macrophages. MiR-155-5p is one of the best characterized miRNAs and recent data indicate that miR-155-5p plays a critical role in various physiological and pathological processes such as hemat …
MiR-155-5p is highly expressed in both activated B- and T-cells and in monocytes/macrophages. MiR-155-5p is one of the best character …
Myeloid cell-specific mutation of Spi1 selectively reduces M2-biased macrophage numbers in skeletal muscle, reduces age-related muscle fibrosis and prevents sarcopenia.
Wang Y, Welc SS, Wehling-Henricks M, Kong Y, Thomas C, Montecino-Rodriguez E, Dorshkind K, Tidball JG. Wang Y, et al. Aging Cell. 2022 Oct;21(10):e13690. doi: 10.1111/acel.13690. Epub 2022 Sep 13. Aging Cell. 2022. PMID: 36098370 Free PMC article.
Cellularity of most myeloid lineage cells was not influenced by the mutation. The Spi1 mutation in bone marrow-derived macrophages in vitro also did not affect expression of transcripts that indicate the M2-biased phenotype. Thus, myeloid cell-targeted mutation of …
Cellularity of most myeloid lineage cells was not influenced by the mutation. The Spi1 mutation in bone marrow-derived macrophages …
Comprehensive Analysis of Immune Implications and Prognostic Value of SPI1 in Gastric Cancer.
Huang J, Chen W, Jie Z, Jiang M. Huang J, et al. Front Oncol. 2022 Feb 14;12:820568. doi: 10.3389/fonc.2022.820568. eCollection 2022. Front Oncol. 2022. PMID: 35237521 Free PMC article.
However, the potential role of SPI1 in gastric cancer (GC) and the correlations between SPI1 and immune infiltration remain unclear. ...CIBERSORT analysis revealed that SPI1 expression was correlated with seven types of TICs (naive B cells, resting memory CD4 …
However, the potential role of SPI1 in gastric cancer (GC) and the correlations between SPI1 and immune infiltration remain un …
Spi1 regulates the microglial/macrophage inflammatory response via the PI3K/AKT/mTOR signaling pathway after intracerebral hemorrhage.
Zhang G, Lu J, Zheng J, Mei S, Li H, Zhang X, Ping A, Gao S, Fang Y, Yu J. Zhang G, et al. Neural Regen Res. 2024 Jan;19(1):161-170. doi: 10.4103/1673-5374.375343. Neural Regen Res. 2024. PMID: 37488863 Free PMC article.
The E26 transformation-specific sequence-related transcription factor Spi1 regulates microglial/macrophage commitment and maturation. However, the effect of Spi1 on intracerebral hemorrhage remains unclear. ...In conclusion, our results suggest that Spi1 …
The E26 transformation-specific sequence-related transcription factor Spi1 regulates microglial/macrophage commitment and matu …
phoP, SPI1, SPI2 and aroA mutants of Salmonella Enteritidis induce a different immune response in chickens.
Elsheimer-Matulova M, Varmuzova K, Kyrova K, Havlickova H, Sisak F, Rahman M, Rychlik I. Elsheimer-Matulova M, et al. Vet Res. 2015 Sep 17;46(1):96. doi: 10.1186/s13567-015-0224-x. Vet Res. 2015. PMID: 26380970 Free PMC article.
In this study we therefore characterized the interactions between chickens and phoP, aroA, SPI1 and SPI2 mutants of S. Enteritidis. First we tested the response of HD11 chicken macrophage-like cell line to S. ...When newly hatched chickens were inocula …
In this study we therefore characterized the interactions between chickens and phoP, aroA, SPI1 and SPI2 mutants of S. Enterit …
SPI1-mediated MIR222HG transcription promotes proneural-to-mesenchymal transition of glioma stem cells and immunosuppressive polarization of macrophages.
Fan Y, Gao Z, Xu J, Wang H, Guo Q, Li B, Li M, Xu H, Qi Y, Zhao S, Qiu W, Pan Z, Wang Q, Xue H, Zhao R, Guo X, Li G. Fan Y, et al. Theranostics. 2023 May 27;13(10):3310-3329. doi: 10.7150/thno.82590. eCollection 2023. Theranostics. 2023. PMID: 37351164 Free PMC article.
Moreover, cotranscribed miR221 and miR222 can be delivered to macrophages via exosomes to target SOCS3, causing immunosuppressive polarization. Finally, PLX-4720 sensitivity is associated with SPI1 expression and acts on MES GSCs to enhance radiosensitivity. ...
Moreover, cotranscribed miR221 and miR222 can be delivered to macrophages via exosomes to target SOCS3, causing immunosuppressive pol …
253 results