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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1994 1
1995 6
1997 4
1999 6
2000 2
2001 6
2002 8
2003 3
2004 2
2005 11
2006 7
2007 10
2008 12
2009 9
2010 10
2011 12
2012 9
2013 13
2014 7
2015 11
2016 8
2017 8
2018 11
2019 13
2020 16
2021 20
2022 13
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216 results
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Salmonella Typhimurium reprograms macrophage metabolism via T3SS effector SopE2 to promote intracellular replication and virulence.
Jiang L, Wang P, Song X, Zhang H, Ma S, Wang J, Li W, Lv R, Liu X, Ma S, Yan J, Zhou H, Huang D, Cheng Z, Yang C, Feng L, Wang L. Jiang L, et al. Nat Commun. 2021 Feb 9;12(1):879. doi: 10.1038/s41467-021-21186-4. Nat Commun. 2021. PMID: 33563986 Free PMC article.
Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S. Typhimurium exhibit upregulated glycolysis and decreased serine synthesis, leading to accumulation of glycolytic intermedi …
Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infect …
Regulation of the MIR155 host gene in physiological and pathological processes.
Elton TS, Selemon H, Elton SM, Parinandi NL. Elton TS, et al. Gene. 2013 Dec 10;532(1):1-12. doi: 10.1016/j.gene.2012.12.009. Epub 2012 Dec 14. Gene. 2013. PMID: 23246696 Review.
MiR-155-5p is highly expressed in both activated B- and T-cells and in monocytes/macrophages. MiR-155-5p is one of the best characterized miRNAs and recent data indicate that miR-155-5p plays a critical role in various physiological and pathological processes such as hemat …
MiR-155-5p is highly expressed in both activated B- and T-cells and in monocytes/macrophages. MiR-155-5p is one of the best character …
[Salmonella pathogenicity islands].
Sırıken B. Sırıken B. Mikrobiyol Bul. 2013 Jan;47(1):181-8. doi: 10.5578/mb.4138. Mikrobiyol Bul. 2013. PMID: 23390917 Free article. Review. Turkish.
Salmonella species are facultative intracellular pathogenic bacteria. They can invade macrophages, dendritic and epithelial cells. The responsible virulence genes for invasion, survival, and extraintestinal spread are located in Salmonella pathogenicity islands (SPIs). ...
Salmonella species are facultative intracellular pathogenic bacteria. They can invade macrophages, dendritic and epithelial cells. Th …
Development and Validation of a Prognostic Gene Signature Correlated With M2 Macrophage Infiltration in Esophageal Squamous Cell Carcinoma.
Yao J, Duan L, Huang X, Liu J, Fan X, Xiao Z, Yan R, Liu H, An G, Hu B, Ge Y. Yao J, et al. Front Oncol. 2021 Dec 3;11:769727. doi: 10.3389/fonc.2021.769727. eCollection 2021. Front Oncol. 2021. PMID: 34926275 Free PMC article.
To identify the basis for these differences in the TME, we performed correlation analyses and found a significant positive correlation with M1 and M2 macrophages and CD8+ T cells, as well as a strong correlation to M2 macrophage surface markers. ...CONCLUSION: This …
To identify the basis for these differences in the TME, we performed correlation analyses and found a significant positive correlation with …
Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes.
Novikova G, Kapoor M, Tcw J, Abud EM, Efthymiou AG, Chen SX, Cheng H, Fullard JF, Bendl J, Liu Y, Roussos P, Björkegren JL, Liu Y, Poon WW, Hao K, Marcora E, Goate AM. Novikova G, et al. Nat Commun. 2021 Mar 12;12(1):1610. doi: 10.1038/s41467-021-21823-y. Nat Commun. 2021. PMID: 33712570 Free PMC article.
Genome-wide association studies (GWAS) have identified more than 40 loci associated with Alzheimer's disease (AD), but the causal variants, regulatory elements, genes and pathways remain largely unknown, impeding a mechanistic understanding of AD pathogenesis. ...Here, we …
Genome-wide association studies (GWAS) have identified more than 40 loci associated with Alzheimer's disease (AD), but the causal var …
The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies.
Su A, Ling F, Vaganay C, Sodaro G, Benaksas C, Dal Bello R, Forget A, Pardieu B, Lin KH, Rutter JC, Bassil CF, Fortin G, Pasanisi J, Antony-Debré I, Alexe G, Benoist JF, Pruvost A, Pikman Y, Qi J, Schlageter MH, Micol JB, Roti G, Cluzeau T, Dombret H, Preudhomme C, Fenouille N, Benajiba L, Golan HM, Stegmaier K, Lobry C, Wood KC, Itzykson R, Puissant A. Su A, et al. Cancer Discov. 2020 Dec;10(12):1894-1911. doi: 10.1158/2159-8290.CD-19-0970. Epub 2020 Aug 21. Cancer Discov. 2020. PMID: 32826232 Free PMC article.
Mechanistically, folate cycle disturbance reduces H3K27/K9 histone methylation and activates a SPI1 transcriptional program counteracting the effect of BET inhibition. ...
Mechanistically, folate cycle disturbance reduces H3K27/K9 histone methylation and activates a SPI1 transcriptional program counterac …
Abnormal expression of colony stimulating factor 1 receptor (CSF1R) and transcription factor PU.1 (SPI1) in the spleen from patients with major psychiatric disorders: A role of brain-spleen axis.
Zhang J, Chang L, Pu Y, Hashimoto K. Zhang J, et al. J Affect Disord. 2020 Jul 1;272:110-115. doi: 10.1016/j.jad.2020.03.128. Epub 2020 Apr 29. J Affect Disord. 2020. PMID: 32379601
Levels of SPI1 in the parietal cortex were not different among the four groups. Interestingly, there was a negative correlation between CSF1R and SPI1 levels in the spleen of the all subjects from four groups. There was also a negative correlation between CSF1R and …
Levels of SPI1 in the parietal cortex were not different among the four groups. Interestingly, there was a negative correlation betwe …
Single-Cell Transcriptomics of Glioblastoma Reveals a Unique Tumor Microenvironment and Potential Immunotherapeutic Target Against Tumor-Associated Macrophage.
Cui X, Wang Q, Zhou J, Wang Y, Xu C, Tong F, Wang H, Kang C. Cui X, et al. Front Oncol. 2021 Aug 9;11:710695. doi: 10.3389/fonc.2021.710695. eCollection 2021. Front Oncol. 2021. PMID: 34434898 Free PMC article.
By comparing the variable gene expression patterns in different clusters and cell types, we identified components and characteristics of TAMs unique to each GBM subtype. Meanwhile, we interrogated the correlation between SPI1 expression and macrophage infiltration i …
By comparing the variable gene expression patterns in different clusters and cell types, we identified components and characteristics of TAM …
phoP, SPI1, SPI2 and aroA mutants of Salmonella Enteritidis induce a different immune response in chickens.
Elsheimer-Matulova M, Varmuzova K, Kyrova K, Havlickova H, Sisak F, Rahman M, Rychlik I. Elsheimer-Matulova M, et al. Vet Res. 2015 Sep 17;46(1):96. doi: 10.1186/s13567-015-0224-x. Vet Res. 2015. PMID: 26380970 Free PMC article.
In this study we therefore characterized the interactions between chickens and phoP, aroA, SPI1 and SPI2 mutants of S. Enteritidis. First we tested the response of HD11 chicken macrophage-like cell line to S. ...When newly hatched chickens were inocula …
In this study we therefore characterized the interactions between chickens and phoP, aroA, SPI1 and SPI2 mutants of S. Enterit …
Comprehensive Analysis of Immune Implications and Prognostic Value of SPI1 in Gastric Cancer.
Huang J, Chen W, Jie Z, Jiang M. Huang J, et al. Front Oncol. 2022 Feb 14;12:820568. doi: 10.3389/fonc.2022.820568. eCollection 2022. Front Oncol. 2022. PMID: 35237521 Free PMC article.
However, the potential role of SPI1 in gastric cancer (GC) and the correlations between SPI1 and immune infiltration remain unclear. ...CIBERSORT analysis revealed that SPI1 expression was correlated with seven types of TICs (naive B cells, resting memory CD4 …
However, the potential role of SPI1 in gastric cancer (GC) and the correlations between SPI1 and immune infiltration remain un …
216 results