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Table representation of search results timeline featuring number of search results per year.

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1944 1
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1952 3
1953 1
1954 4
1956 2
1957 1
1959 1
1961 1
1962 2
1963 16
1964 13
1965 12
1966 7
1967 14
1968 14
1969 9
1970 6
1971 6
1972 6
1973 4
1974 8
1975 4
1976 10
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1978 5
1979 5
1980 9
1981 5
1982 1
1983 5
1984 4
1985 10
1986 8
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1988 5
1989 4
1990 10
1991 3
1992 4
1993 4
1994 3
1995 3
1996 5
1997 7
1998 2
1999 4
2000 4
2001 6
2002 2
2003 8
2004 14
2005 19
2006 26
2007 26
2008 12
2009 14
2010 16
2011 24
2012 12
2013 19
2014 12
2015 7
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688 results

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Page 1
Synephrine and Its Derivative Compound A: Common and Specific Biological Effects.
Dodonova SA, Zhidkova EM, Kryukov AA, Valiev TT, Kirsanov KI, Kulikov EP, Budunova IV, Yakubovskaya MG, Lesovaya EA. Dodonova SA, et al. Int J Mol Sci. 2023 Dec 15;24(24):17537. doi: 10.3390/ijms242417537. Int J Mol Sci. 2023. PMID: 38139366 Free PMC article. Review.
Additionally, we conduct a comparative analysis of the molecular targets and effects of synephrine with those of its metabolite, selective glucocorticoid receptor agonist (SEGRA) Compound A (CpdA), which shares a similar chemical structure with synephrine. ...The re …
Additionally, we conduct a comparative analysis of the molecular targets and effects of synephrine with those of its metabolite, sele …
[Synephrine in dietary supplements and specialized foodstuffs: biological activity, safety and methods of analysis].
Perova IB, Eller KI, Musatov AV, Tymolskaya EV. Perova IB, et al. Vopr Pitan. 2021;90(6):101-113. doi: 10.33029/0042-8833-2021-90-6-101-113. Epub 2021 Oct 26. Vopr Pitan. 2021. PMID: 35032130 Review. Russian.
Because of insufficient safety data, the consumption of synephrine is regulated in the Russian Federation and abroad. The upper permissible level of synephrine consumption in the Russian Federation is 30 mg per day. Various cases of adulteration of DS and SF for wei …
Because of insufficient safety data, the consumption of synephrine is regulated in the Russian Federation and abroad. The upper permi …
p-Synephrine, ephedrine, p-octopamine and m-synephrine: Comparative mechanistic, physiological and pharmacological properties.
Stohs SJ, Shara M, Ray SD. Stohs SJ, et al. Phytother Res. 2020 Aug;34(8):1838-1846. doi: 10.1002/ptr.6649. Epub 2020 Feb 26. Phytother Res. 2020. PMID: 32101364 Free PMC article. Review.
Confusion and misunderstanding exist regarding the lack of cardiovascular and other adverse health effects of p-synephrine and p-octopamine relative to ephedrine and m-synephrine (phenylephrine) which are known for their effects on the cardiovascular system. ...The …
Confusion and misunderstanding exist regarding the lack of cardiovascular and other adverse health effects of p-synephrine and p-octo …
Effects of p-Synephrine during Exercise: A Brief Narrative Review.
Ruiz-Moreno C, Del Coso J, Giráldez-Costas V, González-García J, Gutiérrez-Hellín J. Ruiz-Moreno C, et al. Nutrients. 2021 Jan 15;13(1):233. doi: 10.3390/nu13010233. Nutrients. 2021. PMID: 33467423 Free PMC article. Review.
However, the effects of p-synephrine on fat oxidation during exercise have been investigated in the last few years. The aim of the current discussion is to summarize the evidence on the effects of p-synephrine intake on fat oxidation and performance during exercise. …
However, the effects of p-synephrine on fat oxidation during exercise have been investigated in the last few years. The aim of the cu …
Synephrine: from trace concentrations to massive consumption in weight-loss.
Rossato LG, Costa VM, Limberger RP, Bastos Mde L, Remião F. Rossato LG, et al. Food Chem Toxicol. 2011 Jan;49(1):8-16. doi: 10.1016/j.fct.2010.11.007. Epub 2010 Nov 12. Food Chem Toxicol. 2011. PMID: 21075161 Review.
Synephrine exists in three different positional isomers; however, only p- and m-synephrine have been described in weight-loss products. The alleged effectiveness of synephrine-containing supplements is attributed to the thermogenic effects arising from syn
Synephrine exists in three different positional isomers; however, only p- and m-synephrine have been described in weight-loss
p-Synephrine ameliorates non-alcoholic fatty liver disease by regulating liver-adipose axis via AMPK/NF-kappa B pathway.
Cai WF, Chen QC, Ni Q, Liu L, Liu Q, Yi YK, Jiang CP, Shen CY. Cai WF, et al. J Ethnopharmacol. 2025 May 28;348:119890. doi: 10.1016/j.jep.2025.119890. Epub 2025 Apr 26. J Ethnopharmacol. 2025. PMID: 40294666
However, the effects of p-synephrine in ameliorating non-alcoholic fatty liver disease (NAFLD) were still unclear. AIM OF STUDY: To explore the effects of p-synephrine on HFD-induced NAFLD and its mechanisms. METHODS: NAFLD mice were developed by HFD feeding and tre …
However, the effects of p-synephrine in ameliorating non-alcoholic fatty liver disease (NAFLD) were still unclear. AIM OF STUDY: To e …
p-Synephrine: an overview of physicochemical properties, toxicity, biological and pharmacological activity.
Kulawik M, Bajewska K, Kulawik A. Kulawik M, et al. EXCLI J. 2025 Mar 5;24:381-400. doi: 10.17179/excli2024-8088. eCollection 2025. EXCLI J. 2025. PMID: 40376440 Free PMC article. Review.
p-Synephrine is a popular ingredient in dietary supplements. It is also found in trace amounts in living organisms. ...On the other hand, several health incidents associated with p-synephrine use have been reported in the scientific literature, making the toxicity o …
p-Synephrine is a popular ingredient in dietary supplements. It is also found in trace amounts in living organisms. ...On the other h …
[Risk assessment of synephrine in dietary supplements].
Bakhyia N, Dusemund B, Richter K, Lindtner O, Hirsch-Ernst KI, Schäfer B, Lampen A. Bakhyia N, et al. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2017 Mar;60(3):323-331. doi: 10.1007/s00103-016-2506-5. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2017. PMID: 28058460 Review. German.
Synephrine is a sympathomimetic phenylethylamine derivative that occurs naturally in citrus fruits. ...Some human intervention studies investigating the acute effects of synephrine on blood pressure and heart rate of healthy, normotensive test persons indicate that
Synephrine is a sympathomimetic phenylethylamine derivative that occurs naturally in citrus fruits. ...Some human intervention studie
A review of the receptor-binding properties of p-synephrine as related to its pharmacological effects.
Stohs SJ, Preuss HG, Shara M. Stohs SJ, et al. Oxid Med Cell Longev. 2011;2011:482973. doi: 10.1155/2011/482973. Epub 2011 Aug 1. Oxid Med Cell Longev. 2011. PMID: 21904645 Free PMC article. Review.
Because of structural similarities, the pharmacological effects of p-synephrine are widely assumed to be similar to those of ephedrine, m-synephrine (phenylephrine), and endogenous amine neurotransmitters as norepinephrine and epinephrine. ...This paper summarizes t …
Because of structural similarities, the pharmacological effects of p-synephrine are widely assumed to be similar to those of ephedrin …
Review of Published Bitter Orange Extract and p-Synephrine Adverse Event Clinical Study Case Reports.
Stohs SJ, Ray SD. Stohs SJ, et al. J Diet Suppl. 2020;17(3):355-363. doi: 10.1080/19390211.2019.1577936. Epub 2019 Mar 5. J Diet Suppl. 2020. PMID: 30835576 Review.
p-Synephrine is the primary active ingredient in bitter orange (Citrus aurantium) extract and is present in other citrus species. ...In no case was a direct correlation between the event and p-synephrine made. Although p-synephrine and ephedrine have some str …
p-Synephrine is the primary active ingredient in bitter orange (Citrus aurantium) extract and is present in other citrus species. ... …
688 results