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VEGFR-1 expressed by malignant melanoma-initiating cells is required for tumor growth.
Frank NY, Schatton T, Kim S, Zhan Q, Wilson BJ, Ma J, Saab KR, Osherov V, Widlund HR, Gasser M, Waaga-Gasser AM, Kupper TS, Murphy GF, Frank MH. Frank NY, et al. Among authors: saab kr. Cancer Res. 2011 Feb 15;71(4):1474-85. doi: 10.1158/0008-5472.CAN-10-1660. Epub 2011 Jan 6. Cancer Res. 2011. PMID: 21212411 Free PMC article.
ABCB5 is a limbal stem cell gene required for corneal development and repair.
Ksander BR, Kolovou PE, Wilson BJ, Saab KR, Guo Q, Ma J, McGuire SP, Gregory MS, Vincent WJ, Perez VL, Cruz-Guilloty F, Kao WW, Call MK, Tucker BA, Zhan Q, Murphy GF, Lathrop KL, Alt C, Mortensen LJ, Lin CP, Zieske JD, Frank MH, Frank NY. Ksander BR, et al. Among authors: saab kr. Nature. 2014 Jul 17;511(7509):353-7. doi: 10.1038/nature13426. Epub 2014 Jul 2. Nature. 2014. PMID: 25030174 Free PMC article.
ABCB5-Targeted Chemoresistance Reversal Inhibits Merkel Cell Carcinoma Growth.
Kleffel S, Lee N, Lezcano C, Wilson BJ, Sobolewski K, Saab KR, Mueller H, Zhan Q, Posch C, Elco CP, DoRosario A, Garcia SS, Thakuria M, Wang YE, Wang LC, Murphy GF, Frank MH, Schatton T. Kleffel S, et al. Among authors: saab kr. J Invest Dermatol. 2016 Apr;136(4):838-846. doi: 10.1016/j.jid.2015.12.038. Epub 2016 Jan 29. J Invest Dermatol. 2016. PMID: 26827764 Free PMC article.
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