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Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks.
Khan J, Wei JS, Ringnér M, Saal LH, Ladanyi M, Westermann F, Berthold F, Schwab M, Antonescu CR, Peterson C, Meltzer PS. Khan J, et al. Nat Med. 2001 Jun;7(6):673-9. doi: 10.1038/89044. Nat Med. 2001. PMID: 11385503 Free PMC article.
Expression profiling in cancer using cDNA microarrays.
Khan J, Saal LH, Bittner ML, Chen Y, Trent JM, Meltzer PS. Khan J, et al. Electrophoresis. 1999 Feb;20(2):223-9. doi: 10.1002/(SICI)1522-2683(19990201)20:2<223::AID-ELPS223>3.0.CO;2-A. Electrophoresis. 1999. PMID: 10197427 Review.
cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene.
Khan J, Bittner ML, Saal LH, Teichmann U, Azorsa DO, Gooden GC, Pavan WJ, Trent JM, Meltzer PS. Khan J, et al. Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13264-9. doi: 10.1073/pnas.96.23.13264. Proc Natl Acad Sci U S A. 1999. PMID: 10557309 Free PMC article.
Gene expression profiling in cancer using cDNA microarrays.
Khan J, Saal LH, Bittner ML, Jiang Y, Gooden GC, Glatfelter AA, Meltzer PS. Khan J, et al. Methods Mol Med. 2002;68:205-22. doi: 10.1385/1-59259-135-3:205. Methods Mol Med. 2002. PMID: 11901504 No abstract available.
Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity.
Saal LH, Johansson P, Holm K, Gruvberger-Saal SK, She QB, Maurer M, Koujak S, Ferrando AA, Malmström P, Memeo L, Isola J, Bendahl PO, Rosen N, Hibshoosh H, Ringnér M, Borg A, Parsons R. Saal LH, et al. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7564-9. doi: 10.1073/pnas.0702507104. Epub 2007 Apr 23. Proc Natl Acad Sci U S A. 2007. PMID: 17452630 Free PMC article.
Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair.
Saal LH, Gruvberger-Saal SK, Persson C, Lövgren K, Jumppanen M, Staaf J, Jönsson G, Pires MM, Maurer M, Holm K, Koujak S, Subramaniyam S, Vallon-Christersson J, Olsson H, Su T, Memeo L, Ludwig T, Ethier SP, Krogh M, Szabolcs M, Murty VV, Isola J, Hibshoosh H, Parsons R, Borg A. Saal LH, et al. Nat Genet. 2008 Jan;40(1):102-7. doi: 10.1038/ng.2007.39. Epub 2007 Dec 9. Nat Genet. 2008. PMID: 18066063 Free PMC article.
Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling.
Roswall P, Bocci M, Bartoschek M, Li H, Kristiansen G, Jansson S, Lehn S, Sjölund J, Reid S, Larsson C, Eriksson P, Anderberg C, Cortez E, Saal LH, Orsmark-Pietras C, Cordero E, Haller BK, Häkkinen J, Burvenich IJG, Lim E, Orimo A, Höglund M, Rydén L, Moch H, Scott AM, Eriksson U, Pietras K. Roswall P, et al. Nat Med. 2018 May;24(4):463-473. doi: 10.1038/nm.4494. Epub 2018 Mar 12. Nat Med. 2018. PMID: 29529015 Free PMC article.
Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study.
Staaf J, Glodzik D, Bosch A, Vallon-Christersson J, Reuterswärd C, Häkkinen J, Degasperi A, Amarante TD, Saal LH, Hegardt C, Stobart H, Ehinger A, Larsson C, Rydén L, Loman N, Malmberg M, Kvist A, Ehrencrona H, Davies HR, Borg Å, Nik-Zainal S. Staaf J, et al. Among authors: saal lh. Nat Med. 2019 Oct;25(10):1526-1533. doi: 10.1038/s41591-019-0582-4. Epub 2019 Sep 30. Nat Med. 2019. PMID: 31570822 Free PMC article.
Molecular stratification of metastatic melanoma using gene expression profiling: Prediction of survival outcome and benefit from molecular targeted therapy.
Cirenajwis H, Ekedahl H, Lauss M, Harbst K, Carneiro A, Enoksson J, Rosengren F, Werner-Hartman L, Törngren T, Kvist A, Fredlund E, Bendahl PO, Jirström K, Lundgren L, Howlin J, Borg Å, Gruvberger-Saal SK, Saal LH, Nielsen K, Ringnér M, Tsao H, Olsson H, Ingvar C, Staaf J, Jönsson G. Cirenajwis H, et al. Oncotarget. 2015 May 20;6(14):12297-309. doi: 10.18632/oncotarget.3655. Oncotarget. 2015. PMID: 25909218 Free PMC article.
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