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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.
Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. Sarbassov DD, et al. Among authors: sabatini dm. Curr Biol. 2004 Jul 27;14(14):1296-302. doi: 10.1016/j.cub.2004.06.054. Curr Biol. 2004. PMID: 15268862
Microarrays of cells expressing defined cDNAs.
Ziauddin J, Sabatini DM. Ziauddin J, et al. Among authors: sabatini dm. Nature. 2001 May 3;411(6833):107-10. doi: 10.1038/35075114. Nature. 2001. PMID: 11333987
The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation.
Peng T, Golub TR, Sabatini DM. Peng T, et al. Among authors: sabatini dm. Mol Cell Biol. 2002 Aug;22(15):5575-84. doi: 10.1128/mcb.22.15.5575-5584.2002. Mol Cell Biol. 2002. PMID: 12101249 Free PMC article.
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.
Kim DH, Sarbassov DD, Ali SM, King JE, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. Kim DH, et al. Among authors: sabatini dm. Cell. 2002 Jul 26;110(2):163-75. doi: 10.1016/s0092-8674(02)00808-5. Cell. 2002. PMID: 12150925
Cell-biological applications of transfected-cell microarrays.
Wu RZ, Bailey SN, Sabatini DM. Wu RZ, et al. Among authors: sabatini dm. Trends Cell Biol. 2002 Oct;12(10):485-8. doi: 10.1016/s0962-8924(02)02354-1. Trends Cell Biol. 2002. PMID: 12441253 Review.
Lentivirus-delivered stable gene silencing by RNAi in primary cells.
Stewart SA, Dykxhoorn DM, Palliser D, Mizuno H, Yu EY, An DS, Sabatini DM, Chen IS, Hahn WC, Sharp PA, Weinberg RA, Novina CD. Stewart SA, et al. Among authors: sabatini dm. RNA. 2003 Apr;9(4):493-501. doi: 10.1261/rna.2192803. RNA. 2003. PMID: 12649500 Free PMC article.
GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR.
Kim DH, Sarbassov DD, Ali SM, Latek RR, Guntur KV, Erdjument-Bromage H, Tempst P, Sabatini DM. Kim DH, et al. Among authors: sabatini dm. Mol Cell. 2003 Apr;11(4):895-904. doi: 10.1016/s1097-2765(03)00114-x. Mol Cell. 2003. PMID: 12718876
TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function.
Schalm SS, Fingar DC, Sabatini DM, Blenis J. Schalm SS, et al. Among authors: sabatini dm. Curr Biol. 2003 May 13;13(10):797-806. doi: 10.1016/s0960-9822(03)00329-4. Curr Biol. 2003. PMID: 12747827
Raptor and mTOR: subunits of a nutrient-sensitive complex.
Kim DH, Sabatini DM. Kim DH, et al. Among authors: sabatini dm. Curr Top Microbiol Immunol. 2004;279:259-70. doi: 10.1007/978-3-642-18930-2_15. Curr Top Microbiol Immunol. 2004. PMID: 14560962 Review.
Systematic genome-wide screens of gene function.
Carpenter AE, Sabatini DM. Carpenter AE, et al. Among authors: sabatini dm. Nat Rev Genet. 2004 Jan;5(1):11-22. doi: 10.1038/nrg1248. Nat Rev Genet. 2004. PMID: 14708012 Review. No abstract available.
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