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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2003 3
2004 3
2005 2
2006 5
2007 3
2008 3
2009 1
2010 5
2011 4
2012 8
2013 10
2014 18
2015 15
2016 16
2017 14
2018 12
2019 8
2020 19
2021 10
2022 6
2023 9
2024 8
2025 8
2026 4

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172 results

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Page 1
Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes.
Mueller S, Engleitner T, Maresch R, Zukowska M, Lange S, Kaltenbacher T, Konukiewitz B, Öllinger R, Zwiebel M, Strong A, Yen HY, Banerjee R, Louzada S, Fu B, Seidler B, Götzfried J, Schuck K, Hassan Z, Arbeiter A, Schönhuber N, Klein S, Veltkamp C, Friedrich M, Rad L, Barenboim M, Ziegenhain C, Hess J, Dovey OM, Eser S, Parekh S, Constantino-Casas F, de la Rosa J, Sierra MI, Fraga M, Mayerle J, Klöppel G, Cadiñanos J, Liu P, Vassiliou G, Weichert W, Steiger K, Enard W, Schmid RM, Yang F, Unger K, Schneider G, Varela I, Bradley A, Saur D, Rad R. Mueller S, et al. Among authors: klein s. Nature. 2018 Feb 1;554(7690):62-68. doi: 10.1038/nature25459. Epub 2018 Jan 24. Nature. 2018. PMID: 29364867 Free PMC article.
Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury.
Hackstein CP, Spitzer J, Symeonidis K, Horvatic H, Bedke T, Steglich B, Klein S, Assmus LM, Odainic A, Szlapa J, Kessler N, Beyer M, Schmithausen R, Latz E, Flavell RA, Garbi N, Kurts C, Kümmerer BM, Trebicka J, Roers A, Huber S, Schmidt SV, Knolle PA, Abdullah Z. Hackstein CP, et al. Among authors: klein s. J Hepatol. 2023 Jul;79(1):150-166. doi: 10.1016/j.jhep.2023.02.026. Epub 2023 Mar 2. J Hepatol. 2023. PMID: 36870611 Free article.
Decompensated MASH-Cirrhosis Model by Acute and Toxic Effects of Phenobarbital.
Kraus N, Uschner FE, Moeslein M, Schierwagen R, Gu W, Brol MJ, Fürst E, Grünewald I, Lotersztajn S, Rautou PE, Duran-Güell M, Flores Costa R, Clària J, Trebicka J, Klein S; DECISION. Kraus N, et al. Among authors: klein s. Cells. 2024 Oct 16;13(20):1707. doi: 10.3390/cells13201707. Cells. 2024. PMID: 39451225 Free PMC article.
Hepatocellular Cancer Surveillance in Patients with Advanced Chronic Liver Disease.
Gu W, de Lédinghen V, Aubé C, Krag A, Strassburg C, Castéra L, Dumortier J, Friedrich-Rust M, Pol S, Grgurevic I, Zeleke Y, Praktiknjo M, Schierwagen R, Klein S, Francque S, Gottfriedová H, Sporea I, Schindler P, Rennebaum F, Brol MJ, Schulz M, Uschner FE, Fischer J, Margini C, Wang W, Delamarre A, Best J, Canbay A, Bauer DJM, Simbrunner B, Semmler G, Reiberger T, Boursier J, Rasmussen DN, Vilgrain V, Guibal A, Zeuzem S, Vassord C, Vonghia L, Šenkeříková R, Popescu A, Berzigotti A, Laleman W, Thiele M, Jansen C, Trebicka J. Gu W, et al. Among authors: klein s. NEJM Evid. 2024 Nov;3(11):EVIDoa2400062. doi: 10.1056/EVIDoa2400062. Epub 2024 Oct 22. NEJM Evid. 2024. PMID: 39437136
The postbiotic ReFerm® versus standard nutritional support in advanced alcohol-related liver disease (GALA-POSTBIO): a randomized controlled phase 2 trial.
Hansen JK, Israelsen M, Nishijima S, Stinson SE, Andersen P, Johansen S, Hansen CD, Brol MJ, Klein S, Schierwagen R, Uschner FE, Sulek K, Villesen IF, Lindvig KP, Thorhauge KH, Torp N, Jensen JM, Keller MI, Jensen GH, Detlefsen S, Leeming DJ, Stankevic E, Suvitaival T, Zawadzki A, Kuhn M, Jensen LJ, Karsdal M, Trebicka J, Israelsen H, Legido-Quigley C, Bork P, Arumugam M, Hansen T, Thiele M, Krag A. Hansen JK, et al. Among authors: klein s. Nat Commun. 2025 Jul 1;16(1):5969. doi: 10.1038/s41467-025-60755-9. Nat Commun. 2025. PMID: 40595534 Free PMC article. Clinical Trial.
An optimized peritonitis-induced ACLF model that reproduces the full spectrum of extrahepatic organ failures in mice.
Flores-Costa R, Duran-Güell M, Romero-Grimaldo B, Contreras BJ, Salvatella A, Sánchez-Rodríguez MB, Uschner F, Klein S, Diaz A, Huergo E, Gómez-Cabrero D, Bosch J, Rautou PE, Trebicka J, López-Vicario C, Clària J. Flores-Costa R, et al. Among authors: klein s. Hepatol Commun. 2025 Jun 19;9(7):e0744. doi: 10.1097/HC9.0000000000000744. eCollection 2025 Jul 1. Hepatol Commun. 2025. PMID: 40536682 Free PMC article.
Pathogenetic mechanisms and therapeutic approaches of acute-to-chronic liver failure.
Schierwagen R, Gu W, Brieger A, Brüne B, Ciesek S, Đikić I, Dimmeler S, Geisslinger G, Greten FR, Hermann E, Hildt E, Kempf VAJ, Klein S, Koch I, Mühl H, Müller V, Peiffer KH, Kestner RI, Piiper A, Rohde G, Scholich K, Schulz MH, Storf H, Toptan T, Vasa-Nicotera M, Vehreschild MJGT, Weigert A, Wild PJ, Zeuzem S, Engelmann C; ACLF-I Investigators,; Schaefer L, Welsch C, Trebicka J. Schierwagen R, et al. Among authors: klein s. Am J Physiol Cell Physiol. 2023 Jul 1;325(1):C129-C140. doi: 10.1152/ajpcell.00101.2023. Epub 2023 Jun 5. Am J Physiol Cell Physiol. 2023. PMID: 37273239 Free article. Review.
The transaminase-ω-amidase pathway senses oxidative stress to control glutamine metabolism and α-ketoglutarate levels in endothelial cells.
Herrle N, Malacarne PF, Warwick T, Cabrera-Orefice A, Chen Y, Gheisari M, Chatterjee S, Leisegang MS, Sarakpi T, Wionski S, Lopez M, Kader C, Teichmann T, Drekolia MK, Koch I, Keßler M, Klein S, Erhard Uschner F, Trebicka J, Brunst S, Proschak E, Günther S, Rosas-Lemus M, Baumgarten N, Klatt S, Speer T, Bibli SI, Segarra M, Acker-Palmer A, Wagner JUG, Wittig I, Dimmeler S, Schulz MH, Richards JB, Gilsbach R, T Denton T, Fleming I, Hannibal L, Brandes RP, Rezende F. Herrle N, et al. Among authors: klein s. EMBO J. 2026 Feb;45(3):820-855. doi: 10.1038/s44318-025-00642-7. Epub 2025 Dec 17. EMBO J. 2026. PMID: 41408486 Free PMC article.
Extracellular Matrix Remodeling in Chronic Liver Disease.
Ortiz C, Schierwagen R, Schaefer L, Klein S, Trepat X, Trebicka J. Ortiz C, et al. Among authors: klein s. Curr Tissue Microenviron Rep. 2021;2(3):41-52. doi: 10.1007/s43152-021-00030-3. Epub 2021 Jul 23. Curr Tissue Microenviron Rep. 2021. PMID: 34337431 Free PMC article. Review.
172 results