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A modular and flexible ESC-based mouse model of pancreatic cancer.
Saborowski M, Saborowski A, Morris JP 4th, Bosbach B, Dow LE, Pelletier J, Klimstra DS, Lowe SW. Saborowski M, et al. Among authors: saborowski a. Genes Dev. 2014 Jan 1;28(1):85-97. doi: 10.1101/gad.232082.113. Genes Dev. 2014. PMID: 24395249 Free PMC article.
Generation of focal mutations and large genomic deletions in the pancreas using inducible in vivo genome editing.
Mishra A, Emamgholi F, Erlangga Z, Hartleben B, Unger K, Wolff K, Teichmann U, Kessel M, Woller N, Kühnel F, Dow LE, Manns MP, Vogel A, Lowe SW, Saborowski A, Saborowski M. Mishra A, et al. Among authors: saborowski m, saborowski a. Carcinogenesis. 2020 May 14;41(3):334-344. doi: 10.1093/carcin/bgz108. Carcinogenesis. 2020. PMID: 31170286 Free PMC article.
Disruption of CRAF-mediated MEK activation is required for effective MEK inhibition in KRAS mutant tumors.
Lito P, Saborowski A, Yue J, Solomon M, Joseph E, Gadal S, Saborowski M, Kastenhuber E, Fellmann C, Ohara K, Morikami K, Miura T, Lukacs C, Ishii N, Lowe S, Rosen N. Lito P, et al. Among authors: saborowski m, saborowski a. Cancer Cell. 2014 May 12;25(5):697-710. doi: 10.1016/j.ccr.2014.03.011. Epub 2014 Apr 17. Cancer Cell. 2014. PMID: 24746704 Free PMC article.
Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer In Vivo and In Vitro.
Saborowski A, Wolff K, Spielberg S, Beer B, Hartleben B, Erlangga Z, Becker D, Dow LE, Marhenke S, Woller N, Unger K, Schirmacher P, Manns MP, Marquardt JU, Vogel A, Saborowski M. Saborowski A, et al. Among authors: saborowski m. Hepatol Commun. 2019 Feb 5;3(3):423-436. doi: 10.1002/hep4.1312. eCollection 2019 Mar. Hepatol Commun. 2019. PMID: 30859153 Free PMC article.
Foretinib is a potent inhibitor of oncogenic ROS1 fusion proteins.
Davare MA, Saborowski A, Eide CA, Tognon C, Smith RL, Elferich J, Agarwal A, Tyner JW, Shinde UP, Lowe SW, Druker BJ. Davare MA, et al. Among authors: saborowski a. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19519-24. doi: 10.1073/pnas.1319583110. Epub 2013 Nov 11. Proc Natl Acad Sci U S A. 2013. PMID: 24218589 Free PMC article.
Genetic Mouse Models as In Vivo Tools for Cholangiocarcinoma Research.
Erice O, Vallejo A, Ponz-Sarvise M, Saborowski M, Vogel A, Calvisi DF, Saborowski A, Vicent S. Erice O, et al. Among authors: saborowski m, saborowski a. Cancers (Basel). 2019 Nov 26;11(12):1868. doi: 10.3390/cancers11121868. Cancers (Basel). 2019. PMID: 31769429 Free PMC article. Review.
p53-Independent Induction of p21 Fails to Control Regeneration and Hepatocarcinogenesis in a Murine Liver Injury Model.
Buitrago-Molina LE, Marhenke S, Becker D, Geffers R, Itzel T, Teufel A, Jaeschke H, Lechel A, Unger K, Markovic J, Sharma AD, Marquardt JU, Saborowski M, Saborowski A, Vogel A. Buitrago-Molina LE, et al. Among authors: saborowski m, saborowski a. Cell Mol Gastroenterol Hepatol. 2021;11(5):1387-1404. doi: 10.1016/j.jcmgh.2021.01.006. Epub 2021 Jan 21. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33484913 Free PMC article.
52 results