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Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target.
Schneider RK, Mullally A, Dugourd A, Peisker F, Hoogenboezem R, Van Strien PMH, Bindels EM, Heckl D, Büsche G, Fleck D, Müller-Newen G, Wongboonsin J, Ventura Ferreira M, Puelles VG, Saez-Rodriguez J, Ebert BL, Humphreys BD, Kramann R. Schneider RK, et al. Cell Stem Cell. 2017 Jun 1;20(6):785-800.e8. doi: 10.1016/j.stem.2017.03.008. Epub 2017 Apr 27. Cell Stem Cell. 2017. PMID: 28457748 Free PMC article.
Footprint-based functional analysis of multiomic data.
Dugourd A, Saez-Rodriguez J. Dugourd A, et al. Curr Opin Syst Biol. 2019 Jun;15:82-90. doi: 10.1016/j.coisb.2019.04.002. Curr Opin Syst Biol. 2019. PMID: 32685770 Free PMC article. Review.
Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN.
Gleitz HFE, Dugourd AJF, Leimkühler NB, Snoeren IAM, Fuchs SNR, Menzel S, Ziegler S, Kröger N, Triviai I, Büsche G, Kreipe H, Banjanin B, Pritchard JE, Hoogenboezem R, Bindels EM, Schumacher N, Rose-John S, Elf S, Saez-Rodriguez J, Kramann R, Schneider RK. Gleitz HFE, et al. Blood. 2020 Oct 29;136(18):2051-2064. doi: 10.1182/blood.2019004095. Blood. 2020. PMID: 32726410 Free PMC article.
Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ.
Cappelletti V, Hauser T, Piazza I, Pepelnjak M, Malinovska L, Fuhrer T, Li Y, Dörig C, Boersema P, Gillet L, Grossbach J, Dugourd A, Saez-Rodriguez J, Beyer A, Zamboni N, Caflisch A, de Souza N, Picotti P. Cappelletti V, et al. Cell. 2021 Jan 21;184(2):545-559.e22. doi: 10.1016/j.cell.2020.12.021. Epub 2020 Dec 23. Cell. 2021. PMID: 33357446 Free PMC article.
283 results