Safgren S - Search Results

1

Evaluation of CYP2D6 and efficacy of tamoxifen and raloxifene in women treated for breast cancer chemoprevention: results from the NSABP P1 and P2 clinical trials.

Goetz MP, Schaid DJ, Wickerham DL, Safgren S, Mushiroda T, Kubo M, Batzler A, Costantino JP, Vogel VG, Paik S, Carlson EE, Flockhart DA, Wolmark N, Nakamura Y, Weinshilboum RM, Ingle JN, Ames MM. Goetz MP, et al. Among authors: safgren s. Clin Cancer Res. 2011 Nov 1;17(21):6944-51. doi: 10.1158/1078-0432.CCR-11-0860. Epub 2011 Aug 31. Clin Cancer Res. 2011. PMID: 21880792 Free PMC article. Clinical Trial.

2

A randomized phase II and pharmacokinetic study of dacarbazine in patients with recurrent glioma.

Rajkumar SV, Reid JM, Novotny PJ, Safgren SL, Scheithauer BW, Johnson PS, Nair S, Morton RF, Hatfield AK, Krook JE, Ames MM, Buckner JC; North Central Cancer Treatment Group. Rajkumar SV, et al. Among authors: safgren sl. J Neurooncol. 2000 Sep;49(3):255-61. doi: 10.1023/a:1006454427026. J Neurooncol. 2000. PMID: 11212905 Clinical Trial.

3

Validated high-performance liquid chromatographic assay for simultaneous determination of dacarbazine and the plasma metabolites 5-(3-hydroxymethyl-3-methyl-1-triazeno)imidazole-4-carboxamide and 5-(3-methyl-1-triazeno)imidazole-4-carboxamide.

Safgren SL, Reid JM, Rios R, Ames MM. Safgren SL, et al. J Chromatogr B Biomed Sci Appl. 2001 Apr 15;754(1):91-6. doi: 10.1016/s0378-4347(00)00586-7. J Chromatogr B Biomed Sci Appl. 2001. PMID: 11318431

4

Phase I trial of sequential administration of raltitrexed (Tomudex) and 5-iodo-2'-deoxyuridine (IdUrd).

Galanis E, Goldberg R, Reid J, Atherton P, Sloan J, Pitot H, Rubin J, Adjei AA, Burch P, Safgren SL, Witzig TE, Ames MM, Erlichman C. Galanis E, et al. Among authors: safgren sl. Ann Oncol. 2001 May;12(5):701-7. doi: 10.1023/a:1011182123545. Ann Oncol. 2001. PMID: 11432631 Free article. Clinical Trial.

5

Phase I trial and pharmacokinetics of gemcitabine in children with advanced solid tumors.

Reid JM, Qu W, Safgren SL, Ames MM, Krailo MD, Seibel NL, Kuttesch J, Holcenberg J. Reid JM, et al. J Clin Oncol. 2004 Jun 15;22(12):2445-51. doi: 10.1200/JCO.2004.10.142. J Clin Oncol. 2004. PMID: 15197207 Clinical Trial.

6

Phase I trial of 17-allylamino-17-demethoxygeldanamycin in patients with advanced cancer.

Goetz MP, Toft D, Reid J, Ames M, Stensgard B, Safgren S, Adjei AA, Sloan J, Atherton P, Vasile V, Salazaar S, Adjei A, Croghan G, Erlichman C. Goetz MP, et al. Among authors: safgren s. J Clin Oncol. 2005 Feb 20;23(6):1078-87. doi: 10.1200/JCO.2005.09.119. J Clin Oncol. 2005. PMID: 15718306 Clinical Trial.

7

Phase I and pharmacologic study of infusional topotecan and Carboplatin in relapsed and refractory acute leukemia.

Kaufmann SH, Karp JE, Letendre L, Kottke TJ, Safgren S, Greer J, Gojo I, Atherton P, Svingen PA, Loegering DA, Litzow MR, Sloan JA, Reid JM, Ames MM, Adjei AA, Erlichman C. Kaufmann SH, et al. Among authors: safgren s. Clin Cancer Res. 2005 Sep 15;11(18):6641-9. doi: 10.1158/1078-0432.CCR-05-0817. Clin Cancer Res. 2005. PMID: 16166443 Clinical Trial.

8

Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes.

Goetz MP, Rae JM, Suman VJ, Safgren SL, Ames MM, Visscher DW, Reynolds C, Couch FJ, Lingle WL, Flockhart DA, Desta Z, Perez EA, Ingle JN. Goetz MP, et al. J Clin Oncol. 2005 Dec 20;23(36):9312-8. doi: 10.1200/JCO.2005.03.3266. J Clin Oncol. 2005. PMID: 16361630

9

A phase I trial of twice-weekly 17-allylamino-demethoxy-geldanamycin in patients with advanced cancer.

Nowakowski GS, McCollum AK, Ames MM, Mandrekar SJ, Reid JM, Adjei AA, Toft DO, Safgren SL, Erlichman C. Nowakowski GS, et al. Among authors: safgren sl. Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):6087-93. doi: 10.1158/1078-0432.CCR-06-1015. Clin Cancer Res. 2006. PMID: 17062684 Clinical Trial.

10

The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen.

Goetz MP, Knox SK, Suman VJ, Rae JM, Safgren SL, Ames MM, Visscher DW, Reynolds C, Couch FJ, Lingle WL, Weinshilboum RM, Fritcher EG, Nibbe AM, Desta Z, Nguyen A, Flockhart DA, Perez EA, Ingle JN. Goetz MP, et al. Breast Cancer Res Treat. 2007 Jan;101(1):113-21. doi: 10.1007/s10549-006-9428-0. Epub 2006 Nov 18. Breast Cancer Res Treat. 2007. PMID: 17115111

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