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Adam10 haploinsufficiency causes freckle-like macules in Hairless mice.
Tharmarajah G, Faas L, Reiss K, Saftig P, Young A, Van Raamsdonk CD. Tharmarajah G, et al. Among authors: saftig p. Pigment Cell Melanoma Res. 2012 Sep;25(5):555-65. doi: 10.1111/j.1755-148X.2012.01032.x. Pigment Cell Melanoma Res. 2012. PMID: 22834956
Tetraspanin 3: A central endocytic membrane component regulating the expression of ADAM10, presenilin and the amyloid precursor protein.
Seipold L, Damme M, Prox J, Rabe B, Kasparek P, Sedlacek R, Altmeppen H, Willem M, Boland B, Glatzel M, Saftig P. Seipold L, et al. Among authors: saftig p. Biochim Biophys Acta Mol Cell Res. 2017 Jan;1864(1):217-230. doi: 10.1016/j.bbamcr.2016.11.003. Epub 2016 Nov 3. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 27818272
The sheddase ADAM10 is a potent modulator of prion disease.
Altmeppen HC, Prox J, Krasemann S, Puig B, Kruszewski K, Dohler F, Bernreuther C, Hoxha A, Linsenmeier L, Sikorska B, Liberski PP, Bartsch U, Saftig P, Glatzel M. Altmeppen HC, et al. Among authors: saftig p. Elife. 2015 Feb 5;4:e04260. doi: 10.7554/eLife.04260. Elife. 2015. PMID: 25654651 Free PMC article.
A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of murine liver tissue homeostasis.
Müller M, Wetzel S, Köhn-Gaone J, Chalupsky K, Lüllmann-Rauch R, Barikbin R, Bergmann J, Wöhner B, Zbodakova O, Leuschner I, Martin G, Tiegs G, Rose-John S, Sedlacek R, Tirnitz-Parker JE, Saftig P, Schmidt-Arras D. Müller M, et al. Among authors: saftig p. Oncotarget. 2016 Apr 5;7(14):17431-41. doi: 10.18632/oncotarget.7836. Oncotarget. 2016. PMID: 26942887 Free PMC article.
327 results