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Effect of CYP2C19 polymorphism on serum levels of vitamin B12 in patients on long-term omeprazole treatment.
Sagar M, Janczewska I, Ljungdahl A, Bertilsson L, Seensalu R. Sagar M, et al. Aliment Pharmacol Ther. 1999 Apr;13(4):453-8. doi: 10.1046/j.1365-2036.1999.00490.x. Aliment Pharmacol Ther. 1999. PMID: 10215728
Omeprazole treatment of Korean patients: effects on gastric pH and gastrin release in relation to CYP2C19 geno- and phenotypes.
Roh HK, Kim PS, Lee DH, Tybring G, Sagar M, Park CS, Seensalu R, Bertilsson L. Roh HK, et al. Among authors: sagar m. Basic Clin Pharmacol Toxicol. 2004 Sep;95(3):112-9. doi: 10.1111/j.1742-7843.2004.950302.x. Basic Clin Pharmacol Toxicol. 2004. PMID: 15447734 Clinical Trial.
Omeprazole and CYP2C19 polymorphism: effects of long-term treatment on gastrin, pepsinogen I, and chromogranin A in patients with acid related disorders.
Sagar M, Bertilsson L, Stridsberg M, Kjellin A, Mârdh S, Seensalu R. Sagar M, et al. Aliment Pharmacol Ther. 2000 Nov;14(11):1495-502. doi: 10.1046/j.1365-2036.2000.00835.x. Aliment Pharmacol Ther. 2000. PMID: 11069321
Effects of omeprazole on intragastric pH and plasma gastrin are dependent on the CYP2C19 polymorphism.
Sagar M, Tybring G, Dahl ML, Bertilsson L, Seensalu R. Sagar M, et al. Gastroenterology. 2000 Sep;119(3):670-6. doi: 10.1053/gast.2000.16515. Gastroenterology. 2000. PMID: 10982760
Comparison of the effect of lansoprazole and omeprazole on intragastric acidity and gastroesophageal reflux in patients with gastroesophageal reflux disease.
Janczewska I, Sagar M, Sjöstedt S, Hammarlund B, Iwarzon M, Seensalu R. Janczewska I, et al. Among authors: sagar m. Scand J Gastroenterol. 1998 Dec;33(12):1239-43. doi: 10.1080/00365529850172304. Scand J Gastroenterol. 1998. PMID: 9930385 Clinical Trial.
Prolonged and profound acid inhibition is crucial in Helicobacter pylori treatment with a proton pump inhibitor combined with amoxicillin.
Sjöstedt S, Sagar M, Lindberg G, Wikström B, Nord CE, Seensalu R. Sjöstedt S, et al. Among authors: sagar m. Scand J Gastroenterol. 1998 Jan;33(1):39-43. Scand J Gastroenterol. 1998. PMID: 9489906
Interphenotype differences in disposition and effect on gastrin levels of omeprazole--suitability of omeprazole as a probe for CYP2C19.
Chang M, Tybring G, Dahl ML, Götharson E, Sagar M, Seensalu R, Bertilsson L. Chang M, et al. Among authors: sagar m. Br J Clin Pharmacol. 1995 May;39(5):511-8. doi: 10.1111/j.1365-2125.1995.tb04488.x. Br J Clin Pharmacol. 1995. PMID: 7669487 Free PMC article.
CYP2C19 genotype and phenotype determined with omeprazole in patients with acid-related disorders with and without Helicobacter pylori infection.
Sagar M, Seensalu R, Tybring G, Dahl ML, Bertilsson L. Sagar M, et al. Scand J Gastroenterol. 1998 Oct;33(10):1034-8. doi: 10.1080/003655298750026714. Scand J Gastroenterol. 1998. PMID: 9829356
The effects of dose and timing of esomeprazole administration on 24-h, daytime and night-time acid inhibition in healthy volunteers.
Wilder-Smith C, Röhss K, Bokelund Singh S, Sagar M, Nagy P. Wilder-Smith C, et al. Among authors: sagar m. Aliment Pharmacol Ther. 2010 Nov;32(10):1249-56. doi: 10.1111/j.1365-2036.2010.04469.x. Epub 2010 Sep 29. Aliment Pharmacol Ther. 2010. PMID: 20955444 Clinical Trial.
Acid control cannot be improved with a modified-release formulation of a proton pump inhibitor compared with twice-daily dosing of the conventional formulation.
Röhss K, Wilder-Smith C, Bokelund-Singh S, Sagar M, Nagy P. Röhss K, et al. Among authors: sagar m. Dig Dis Sci. 2010 Dec;55(12):3423-9. doi: 10.1007/s10620-010-1176-7. Epub 2010 Mar 18. Dig Dis Sci. 2010. PMID: 20238247 Clinical Trial.
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