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Effect of ulixertinib, a novel ERK1/2 inhibitor, on the QT/QTc interval in patients with advanced solid tumor malignancies.
Mendzelevski B, Ferber G, Janku F, Li BT, Sullivan RJ, Welsch D, Chi W, Jackson J, Weng O, Sager PT. Mendzelevski B, et al. Among authors: sager pt. Cancer Chemother Pharmacol. 2018 Jun;81(6):1129-1141. doi: 10.1007/s00280-018-3564-1. Epub 2018 Mar 30. Cancer Chemother Pharmacol. 2018. PMID: 29603015 Free PMC article. Clinical Trial.
Scientific white paper on concentration-QTc modeling.
Garnett C, Bonate PL, Dang Q, Ferber G, Huang D, Liu J, Mehrotra D, Riley S, Sager P, Tornoe C, Wang Y. Garnett C, et al. J Pharmacokinet Pharmacodyn. 2018 Jun;45(3):383-397. doi: 10.1007/s10928-017-9558-5. Epub 2017 Dec 5. J Pharmacokinet Pharmacodyn. 2018. PMID: 29209907 Review.
Correction to: Scientific white paper on concentration-QTc modeling.
Garnett C, Bonate PL, Dang Q, Ferber G, Huang D, Liu J, Mehrotra D, Riley S, Sager P, Tornoe C, Wang Y. Garnett C, et al. J Pharmacokinet Pharmacodyn. 2018 Jun;45(3):399. doi: 10.1007/s10928-017-9565-6. J Pharmacokinet Pharmacodyn. 2018. PMID: 29330761
Clinical Development Approaches and Statistical Methodologies to Prospectively Assess the Cardiovascular Risk of New Antidiabetic Therapies for Type 2 Diabetes.
Geiger MJ, Mehta C, Turner JR, Arbet-Engels C, Hantel S, Hirshberg B, Koglin J, Mendzelevski B, Sager PT, Shapiro D, Stewart M, Todaro TG, Gaydos B. Geiger MJ, et al. Among authors: sager pt. Ther Innov Regul Sci. 2015 Jan;49(1):50-64. doi: 10.1177/2168479014549860. Ther Innov Regul Sci. 2015. PMID: 30222452
Influence of Meals and Glycemic Changes on QT Interval Dynamics.
Cirincione B, Sager PT, Mager DE. Cirincione B, et al. Among authors: sager pt. J Clin Pharmacol. 2017 Aug;57(8):966-976. doi: 10.1002/jcph.933. Epub 2017 May 22. J Clin Pharmacol. 2017. PMID: 28543601 Free PMC article. Clinical Trial.
119 results