Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

14 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
The role of Rho in G protein-coupled receptor signal transduction.
Sah VP, Seasholtz TM, Sagi SA, Brown JH. Sah VP, et al. Among authors: sagi sa. Annu Rev Pharmacol Toxicol. 2000;40:459-89. doi: 10.1146/annurev.pharmtox.40.1.459. Annu Rev Pharmacol Toxicol. 2000. PMID: 10836144 Review.
Physical and functional interactions of Galphaq with Rho and its exchange factors.
Sagi SA, Seasholtz TM, Kobiashvili M, Wilson BA, Toksoz D, Brown JH. Sagi SA, et al. J Biol Chem. 2001 May 4;276(18):15445-52. doi: 10.1074/jbc.M008961200. Epub 2001 Feb 6. J Biol Chem. 2001. PMID: 11278452 Free PMC article.
Rho-mediated cytoskeletal rearrangement in response to LPA is functionally antagonized by Rac1 and PIP2.
Seasholtz TM, Radeff-Huang J, Sagi SA, Matteo R, Weems JM, Cohen AS, Feramisco JR, Brown JH. Seasholtz TM, et al. Among authors: sagi sa. J Neurochem. 2004 Oct;91(2):501-12. doi: 10.1111/j.1471-4159.2004.02749.x. J Neurochem. 2004. PMID: 15447683 Free article.
Abeta42-lowering nonsteroidal anti-inflammatory drugs preserve intramembrane cleavage of the amyloid precursor protein (APP) and ErbB-4 receptor and signaling through the APP intracellular domain.
Weggen S, Eriksen JL, Sagi SA, Pietrzik CU, Golde TE, Koo EH. Weggen S, et al. Among authors: sagi sa. J Biol Chem. 2003 Aug 15;278(33):30748-54. doi: 10.1074/jbc.M304824200. Epub 2003 May 31. J Biol Chem. 2003. PMID: 12777371 Free article.
Substrate sequence influences γ-secretase modulator activity, role of the transmembrane domain of the amyloid precursor protein.
Sagi SA, Lessard CB, Winden KD, Maruyama H, Koo JC, Weggen S, Kukar TL, Golde TE, Koo EH. Sagi SA, et al. J Biol Chem. 2011 Nov 18;286(46):39794-803. doi: 10.1074/jbc.M111.277228. Epub 2011 Aug 25. J Biol Chem. 2011. PMID: 21868380 Free PMC article.
A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity.
Weggen S, Eriksen JL, Das P, Sagi SA, Wang R, Pietrzik CU, Findlay KA, Smith TE, Murphy MP, Bulter T, Kang DE, Marquez-Sterling N, Golde TE, Koo EH. Weggen S, et al. Among authors: sagi sa. Nature. 2001 Nov 8;414(6860):212-6. doi: 10.1038/35102591. Nature. 2001. PMID: 11700559
The non-cyclooxygenase targets of non-steroidal anti-inflammatory drugs, lipoxygenases, peroxisome proliferator-activated receptor, inhibitor of kappa B kinase, and NF kappa B, do not reduce amyloid beta 42 production.
Sagi SA, Weggen S, Eriksen J, Golde TE, Koo EH. Sagi SA, et al. J Biol Chem. 2003 Aug 22;278(34):31825-30. doi: 10.1074/jbc.M303588200. Epub 2003 Jun 12. J Biol Chem. 2003. PMID: 12805355 Free article.
Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity.
Weggen S, Eriksen JL, Sagi SA, Pietrzik CU, Ozols V, Fauq A, Golde TE, Koo EH. Weggen S, et al. Among authors: sagi sa. J Biol Chem. 2003 Aug 22;278(34):31831-7. doi: 10.1074/jbc.M303592200. Epub 2003 Jun 12. J Biol Chem. 2003. PMID: 12805356 Free article.
Substrate-targeting gamma-secretase modulators.
Kukar TL, Ladd TB, Bann MA, Fraering PC, Narlawar R, Maharvi GM, Healy B, Chapman R, Welzel AT, Price RW, Moore B, Rangachari V, Cusack B, Eriksen J, Jansen-West K, Verbeeck C, Yager D, Eckman C, Ye W, Sagi S, Cottrell BA, Torpey J, Rosenberry TL, Fauq A, Wolfe MS, Schmidt B, Walsh DM, Koo EH, Golde TE. Kukar TL, et al. Among authors: sagi s. Nature. 2008 Jun 12;453(7197):925-9. doi: 10.1038/nature07055. Nature. 2008. PMID: 18548070 Free PMC article.
Inhibitors of Rho-kinase modulate amyloid-beta (Abeta) secretion but lack selectivity for Abeta42.
Leuchtenberger S, Kummer MP, Kukar T, Czirr E, Teusch N, Sagi SA, Berdeaux R, Pietrzik CU, Ladd TB, Golde TE, Koo EH, Weggen S. Leuchtenberger S, et al. Among authors: sagi sa. J Neurochem. 2006 Jan;96(2):355-65. doi: 10.1111/j.1471-4159.2005.03553.x. Epub 2005 Nov 21. J Neurochem. 2006. PMID: 16300630 Free article.
14 results
Jump to page
Feedback