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Neurotrophic factors as novel therapeutics for neuropathic pain.
Sah DW, Ossipo MH, Porreca F. Sah DW, et al. Nat Rev Drug Discov. 2003 Jun;2(6):460-72. doi: 10.1038/nrd1107. Nat Rev Drug Discov. 2003. PMID: 12776221 Review.
Gene therapy for neurological disorders: progress and prospects.
Deverman BE, Ravina BM, Bankiewicz KS, Paul SM, Sah DWY. Deverman BE, et al. Among authors: sah dwy. Nat Rev Drug Discov. 2018 Sep;17(9):641-659. doi: 10.1038/nrd.2018.110. Epub 2018 Aug 10. Nat Rev Drug Discov. 2018. PMID: 30093643 Review.
Oligonucleotide therapeutic approaches for Huntington disease.
Sah DW, Aronin N. Sah DW, et al. J Clin Invest. 2011 Feb;121(2):500-7. doi: 10.1172/JCI45130. Epub 2011 Feb 1. J Clin Invest. 2011. PMID: 21285523 Free PMC article. Review.
Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides.
Iwamoto N, Butler DCD, Svrzikapa N, Mohapatra S, Zlatev I, Sah DWY, Meena, Standley SM, Lu G, Apponi LH, Frank-Kamenetsky M, Zhang JJ, Vargeese C, Verdine GL. Iwamoto N, et al. Among authors: sah dwy. Nat Biotechnol. 2017 Sep;35(9):845-851. doi: 10.1038/nbt.3948. Epub 2017 Aug 21. Nat Biotechnol. 2017. PMID: 28829437
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics.
Akinc A, Zumbuehl A, Goldberg M, Leshchiner ES, Busini V, Hossain N, Bacallado SA, Nguyen DN, Fuller J, Alvarez R, Borodovsky A, Borland T, Constien R, de Fougerolles A, Dorkin JR, Narayanannair Jayaprakash K, Jayaraman M, John M, Koteliansky V, Manoharan M, Nechev L, Qin J, Racie T, Raitcheva D, Rajeev KG, Sah DW, Soutschek J, Toudjarska I, Vornlocher HP, Zimmermann TS, Langer R, Anderson DG. Akinc A, et al. Nat Biotechnol. 2008 May;26(5):561-9. doi: 10.1038/nbt1402. Epub 2008 Apr 27. Nat Biotechnol. 2008. PMID: 18438401 Free PMC article.
RNAi therapeutics: a potential new class of pharmaceutical drugs.
Bumcrot D, Manoharan M, Koteliansky V, Sah DW. Bumcrot D, et al. Nat Chem Biol. 2006 Dec;2(12):711-9. doi: 10.1038/nchembio839. Nat Chem Biol. 2006. PMID: 17108989 Free PMC article. Review.
GFRalpha3 is expressed predominantly in nociceptive sensory neurons.
Orozco OE, Walus L, Sah DW, Pepinsky RB, Sanicola M. Orozco OE, et al. Eur J Neurosci. 2001 Jun;13(11):2177-82. doi: 10.1046/j.0953-816x.2001.01596.x. Eur J Neurosci. 2001. PMID: 11422460
TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration.
Shao Z, Browning JL, Lee X, Scott ML, Shulga-Morskaya S, Allaire N, Thill G, Levesque M, Sah D, McCoy JM, Murray B, Jung V, Pepinsky RB, Mi S. Shao Z, et al. Neuron. 2005 Feb 3;45(3):353-9. doi: 10.1016/j.neuron.2004.12.050. Neuron. 2005. PMID: 15694322
LINGO-1 negatively regulates myelination by oligodendrocytes.
Mi S, Miller RH, Lee X, Scott ML, Shulag-Morskaya S, Shao Z, Chang J, Thill G, Levesque M, Zhang M, Hession C, Sah D, Trapp B, He Z, Jung V, McCoy JM, Pepinsky RB. Mi S, et al. Nat Neurosci. 2005 Jun;8(6):745-51. doi: 10.1038/nn1460. Epub 2005 May 15. Nat Neurosci. 2005. PMID: 15895088
A neutralizing anti-Nogo66 receptor monoclonal antibody reverses inhibition of neurite outgrowth by central nervous system myelin.
Li W, Walus L, Rabacchi SA, Jirik A, Chang E, Schauer J, Zheng BH, Benedetti NJ, Liu BP, Choi E, Worley D, Silvian L, Mo W, Mullen C, Yang W, Strittmatter SM, Sah DW, Pepinsky B, Lee DH. Li W, et al. J Biol Chem. 2004 Oct 15;279(42):43780-8. doi: 10.1074/jbc.M401803200. Epub 2004 Aug 5. J Biol Chem. 2004. PMID: 15297463
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