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Mechanisms of cancer cell invasion.
Sahai E. Sahai E. Curr Opin Genet Dev. 2005 Feb;15(1):87-96. doi: 10.1016/j.gde.2004.12.002. Curr Opin Genet Dev. 2005. PMID: 15661538 Review.
Transformation mediated by RhoA requires activity of ROCK kinases.
Sahai E, Ishizaki T, Narumiya S, Treisman R. Sahai E, et al. Curr Biol. 1999 Feb 11;9(3):136-45. doi: 10.1016/s0960-9822(99)80067-0. Curr Biol. 1999. PMID: 10021386
RHO-GTPases and cancer.
Sahai E, Marshall CJ. Sahai E, et al. Nat Rev Cancer. 2002 Feb;2(2):133-42. doi: 10.1038/nrc725. Nat Rev Cancer. 2002. PMID: 12635176 Review.
p53 moves into control of cell morphology.
Sahai E. Sahai E. Mol Interv. 2002 Sep;2(5):286-9. doi: 10.1124/mi.2.5.286. Mol Interv. 2002. PMID: 14993382 No abstract available.
Tumor cells caught in the act of invading: their strategy for enhanced cell motility.
Wang W, Goswami S, Sahai E, Wyckoff JB, Segall JE, Condeelis JS. Wang W, et al. Trends Cell Biol. 2005 Mar;15(3):138-45. doi: 10.1016/j.tcb.2005.01.003. Trends Cell Biol. 2005. PMID: 15752977
Tumor cell migration in three dimensions.
Hooper S, Marshall JF, Sahai E. Hooper S, et al. Methods Enzymol. 2006;406:625-43. doi: 10.1016/S0076-6879(06)06049-6. Methods Enzymol. 2006. PMID: 16472693
It is clear that two-dimensional substrates do not mimic the in vivo environment accurately, and recent work using three-dimensional environments has revealed many different mechanisms of cell migration (Abbott, 2003; Sahai and Marshall, 2003; Wolf et al., 2003). ...
It is clear that two-dimensional substrates do not mimic the in vivo environment accurately, and recent work using three-dimensional environ …
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