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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 3
1998 1
2000 4
2002 3
2003 2
2004 3
2005 1
2006 2
2007 1
2008 1
2009 3
2010 5
2011 3
2012 2
2013 4
2014 5
2015 3
2016 6
2017 5
2018 2
2019 1
2020 1
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57 results
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Page 1
Therapeutic targeting of the angiopoietin-TIE pathway.
Saharinen P, Eklund L, Alitalo K. Saharinen P, et al. Nat Rev Drug Discov. 2017 Sep;16(9):635-661. doi: 10.1038/nrd.2016.278. Epub 2017 May 19. Nat Rev Drug Discov. 2017. PMID: 28529319 Review.
Angiopoietin-Tie signalling in the cardiovascular and lymphatic systems.
Eklund L, Kangas J, Saharinen P. Eklund L, et al. Among authors: saharinen p. Clin Sci (Lond). 2017 Jan 1;131(1):87-103. doi: 10.1042/CS20160129. Clin Sci (Lond). 2017. PMID: 27941161 Free PMC article. Review.
Tie1 controls angiopoietin function in vascular remodeling and inflammation.
Korhonen EA, Lampinen A, Giri H, Anisimov A, Kim M, Allen B, Fang S, D'Amico G, Sipilä TJ, Lohela M, Strandin T, Vaheri A, Ylä-Herttuala S, Koh GY, McDonald DM, Alitalo K, Saharinen P. Korhonen EA, et al. Among authors: saharinen p. J Clin Invest. 2016 Sep 1;126(9):3495-510. doi: 10.1172/JCI84923. Epub 2016 Aug 22. J Clin Invest. 2016. PMID: 27548530 Free PMC article.
Targeting β1-integrin inhibits vascular leakage in endotoxemia.
Hakanpaa L, Kiss EA, Jacquemet G, Miinalainen I, Lerche M, Guzmán C, Mervaala E, Eklund L, Ivaska J, Saharinen P. Hakanpaa L, et al. Among authors: saharinen p. Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6467-E6476. doi: 10.1073/pnas.1722317115. Epub 2018 Jun 25. Proc Natl Acad Sci U S A. 2018. PMID: 29941602 Free PMC article.
Endothelial destabilization by angiopoietin-2 via integrin β1 activation.
Hakanpaa L, Sipila T, Leppanen VM, Gautam P, Nurmi H, Jacquemet G, Eklund L, Ivaska J, Alitalo K, Saharinen P. Hakanpaa L, et al. Among authors: saharinen p. Nat Commun. 2015 Jan 30;6:5962. doi: 10.1038/ncomms6962. Nat Commun. 2015. PMID: 25635707 Free PMC article.
SnapShot: Angiopoietins and Their Functions.
Saharinen P, Leppänen VM, Alitalo K. Saharinen P, et al. Cell. 2017 Oct 19;171(3):724-724.e1. doi: 10.1016/j.cell.2017.10.009. Cell. 2017. PMID: 29053972 Free article.
Receptor tyrosine kinase-mediated angiogenesis.
Jeltsch M, Leppänen VM, Saharinen P, Alitalo K. Jeltsch M, et al. Among authors: saharinen p. Cold Spring Harb Perspect Biol. 2013 Sep 1;5(9):a009183. doi: 10.1101/cshperspect.a009183. Cold Spring Harb Perspect Biol. 2013. PMID: 24003209 Free PMC article. Review.
Angiopoietin signaling in the vasculature.
Eklund L, Saharinen P. Eklund L, et al. Among authors: saharinen p. Exp Cell Res. 2013 May 15;319(9):1271-80. doi: 10.1016/j.yexcr.2013.03.011. Epub 2013 Mar 13. Exp Cell Res. 2013. PMID: 23500414 Review.
Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and β1-integrin activation.
Pekkonen P, Alve S, Balistreri G, Gramolelli S, Tatti-Bugaeva O, Paatero I, Niiranen O, Tuohinto K, Perälä N, Taiwo A, Zinovkina N, Repo P, Icay K, Ivaska J, Saharinen P, Hautaniemi S, Lehti K, Ojala PM. Pekkonen P, et al. Among authors: saharinen p. Elife. 2018 May 1;7:e32490. doi: 10.7554/eLife.32490. Elife. 2018. PMID: 29712618 Free PMC article.
Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization.
Leppänen VM, Saharinen P, Alitalo K. Leppänen VM, et al. Among authors: saharinen p. Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4376-4381. doi: 10.1073/pnas.1616166114. Epub 2017 Apr 10. Proc Natl Acad Sci U S A. 2017. PMID: 28396439 Free PMC article.
57 results
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