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Disrupting D1-NMDA or D2-NMDA receptor heteromerization prevents cocaine's rewarding effects but preserves natural reward processing.
Sci Adv. 2021 Oct 22;7(43):eabg5970. doi: 10.1126/sciadv.abg5970. Epub 2021 Oct 20.
Sci Adv. 2021.
PMID: 34669474
Free PMC article.
Modulation and functions of dopamine receptor heteromers in drugs of abuse-induced adaptations.
Andrianarivelo A, Saint-Jour E, Walle R, Trifilieff P, Vanhoutte P.
Andrianarivelo A, et al. Among authors: saint jour e.
Neuropharmacology. 2019 Jul 1;152:42-50. doi: 10.1016/j.neuropharm.2018.12.003. Epub 2018 Dec 4.
Neuropharmacology. 2019.
PMID: 30529032
Free article.
Review.
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Npas4 regulates medium spiny neuron physiology and gates cocaine-induced hyperlocomotion.
Lissek T, Andrianarivelo A, Saint-Jour E, Allichon MC, Bauersachs HG, Nassar M, Piette C, Pruunsild P, Tan YW, Forget B, Heck N, Caboche J, Venance L, Vanhoutte P, Bading H.
Lissek T, et al. Among authors: saint jour e.
EMBO Rep. 2021 Dec 6;22(12):e51882. doi: 10.15252/embr.202051882. Epub 2021 Oct 18.
EMBO Rep. 2021.
PMID: 34661342
Free PMC article.
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Activity-Regulated Cytoskeleton-Associated Protein Accumulates in the Nucleus in Response to Cocaine and Acts as a Brake on Chromatin Remodeling and Long-Term Behavioral Alterations.
Salery M, Dos Santos M, Saint-Jour E, Moumné L, Pagès C, Kappès V, Parnaudeau S, Caboche J, Vanhoutte P.
Salery M, et al. Among authors: saint jour e.
Biol Psychiatry. 2017 Apr 1;81(7):573-584. doi: 10.1016/j.biopsych.2016.05.025. Epub 2016 Jun 16.
Biol Psychiatry. 2017.
PMID: 27567310
Free article.
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SWI/SNF chromatin remodeler complex within the reward pathway is required for behavioral adaptations to stress.
Zayed A, Baranowski C, Compagnion AC, Vernochet C, Karaki S, Cuttoli RD, Saint-Jour E, Bhattacharya S, Marti F, Vanhoutte P, Yaniv M, Faure P, Barik J, Amar L, Tronche F, Parnaudeau S.
Zayed A, et al. Among authors: saint jour e.
Nat Commun. 2022 Apr 4;13(1):1807. doi: 10.1038/s41467-022-29380-8.
Nat Commun. 2022.
PMID: 35379786
Free PMC article.
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