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8,425 results
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2-(2-Phenylmorpholin-4-yl)pyrimidin-4(3H)-ones; a new class of potent, selective and orally active glycogen synthase kinase-3β inhibitors.
Fukunaga K, Uehara F, Aritomo K, Shoda A, Hiki S, Okuyama M, Usui Y, Watanabe K, Yamakoshi K, Kohara T, Hanano T, Tanaka H, Tsuchiya S, Sunada S, Saito K, Eguchi J, Yuki S, Asano S, Tanaka S, Mori A, Yamagami K, Baba H, Horikawa T, Fujimura M. Fukunaga K, et al. Among authors: saito k. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6933-7. doi: 10.1016/j.bmcl.2013.09.020. Epub 2013 Sep 21. Bioorg Med Chem Lett. 2013. PMID: 24176395
Discovery of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally-active GSK-3β inhibitors for Alzheimer's disease.
Fukunaga K, Sakai D, Watanabe K, Nakayama K, Kohara T, Tanaka H, Sunada S, Nabeno M, Okamoto M, Saito K, Eguchi J, Mori A, Tanaka S, Inazawa K, Horikawa T. Fukunaga K, et al. Among authors: saito k. Bioorg Med Chem Lett. 2015 Mar 1;25(5):1086-91. doi: 10.1016/j.bmcl.2015.01.005. Epub 2015 Jan 13. Bioorg Med Chem Lett. 2015. PMID: 25655721
Discovery of novel 2-(4-aryl-2-methylpiperazin-1-yl)-pyrimidin-4-ones as glycogen synthase kinase-3β inhibitors.
Kohara T, Nakayama K, Watanabe K, Kusaka SI, Sakai D, Tanaka H, Fukunaga K, Sunada S, Nabeno M, Saito KI, Eguchi JI, Mori A, Tanaka S, Bessho T, Takiguchi-Hayashi K, Horikawa T. Kohara T, et al. Among authors: saito ki. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3733-3738. doi: 10.1016/j.bmcl.2017.06.077. Epub 2017 Jul 5. Bioorg Med Chem Lett. 2017. PMID: 28712706
Discovery of novel 2-(3-phenylpiperazin-1-yl)-pyrimidin-4-ones as glycogen synthase kinase-3β inhibitors.
Usui Y, Uehara F, Hiki S, Watanabe K, Tanaka H, Shouda A, Yokoshima S, Aritomo K, Adachi T, Fukunaga K, Sunada S, Nabeno M, Saito KI, Eguchi JI, Yamagami K, Asano S, Tanaka S, Yuki S, Yoshii N, Fujimura M, Horikawa T. Usui Y, et al. Among authors: saito ki. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3726-3732. doi: 10.1016/j.bmcl.2017.06.078. Epub 2017 Jul 5. Bioorg Med Chem Lett. 2017. PMID: 28712708
8,425 results