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Functional analysis of four naturally occurring variants of human constitutive androstane receptor.
Ikeda S, Kurose K, Jinno H, Sai K, Ozawa S, Hasegawa R, Komamura K, Kotake T, Morishita H, Kamakura S, Kitakaze M, Tomoike H, Tamura T, Yamamoto N, Kunitoh H, Yamada Y, Ohe Y, Shimada Y, Shirao K, Kubota K, Minami H, Ohtsu A, Yoshida T, Saijo N, Saito Y, Sawada J. Ikeda S, et al. Among authors: saito y. Mol Genet Metab. 2005 Sep-Oct;86(1-2):314-9. doi: 10.1016/j.ymgme.2005.05.011. Epub 2005 Jun 28. Mol Genet Metab. 2005. PMID: 15990349
Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population.
Fukushima-Uesaka H, Saito Y, Watanabe H, Shiseki K, Saeki M, Nakamura T, Kurose K, Sai K, Komamura K, Ueno K, Kamakura S, Kitakaze M, Hanai S, Nakajima T, Matsumoto K, Saito H, Goto Y, Kimura H, Katoh M, Sugai K, Minami N, Shirao K, Tamura T, Yamamoto N, Minami H, Ohtsu A, Yoshida T, Saijo N, Kitamura Y, Kamatani N, Ozawa S, Sawada J. Fukushima-Uesaka H, et al. Among authors: saito h, saito y. Hum Mutat. 2004 Jan;23(1):100. doi: 10.1002/humu.9210. Hum Mutat. 2004. PMID: 14695543
Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR): one variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region.
Koyano S, Kurose K, Saito Y, Ozawa S, Hasegawa R, Komamura K, Ueno K, Kamakura S, Kitakaze M, Nakajima T, Matsumoto K, Akasawa A, Saito H, Sawada J. Koyano S, et al. Among authors: saito h, saito y. Drug Metab Dispos. 2004 Jan;32(1):149-54. doi: 10.1124/dmd.32.1.149. Drug Metab Dispos. 2004. PMID: 14709632
Novel nonsynonymous single nucleotide polymorphisms in the CYP2D6 gene.
Soyama A, Kubo T, Miyajima A, Saito Y, Shiseki K, Komamura K, Ueno K, Kamakura S, Kitakaze M, Tomoike H, Ozawa S, Sawada J. Soyama A, et al. Among authors: saito y. Drug Metab Pharmacokinet. 2004 Aug;19(4):313-9. doi: 10.2133/dmpk.19.313. Drug Metab Pharmacokinet. 2004. PMID: 15499201 Free article.
Genetic variations of the AHR gene encoding aryl hydrocarbon receptor in a Japanese population.
Fukushima-Uesaka H, Sai K, Maekawa K, Koyano S, Kaniwa N, Ozawa S, Kawamoto M, Kamatani N, Komamura K, Kamakura S, Kitakaze M, Tomoike H, Ueno K, Minami H, Ohtsu A, Shirao K, Yoshida T, Saijo N, Saito Y, Sawada J. Fukushima-Uesaka H, et al. Among authors: saito y. Drug Metab Pharmacokinet. 2004 Aug;19(4):320-6. doi: 10.2133/dmpk.19.320. Drug Metab Pharmacokinet. 2004. PMID: 15499202 Free article.
Functional characterization of five novel CYP2C8 variants, G171S, R186X, R186G, K247R, and K383N, found in a Japanese population.
Hichiya H, Tanaka-Kagawa T, Soyama A, Jinno H, Koyano S, Katori N, Matsushima E, Uchiyama S, Tokunaga H, Kimura H, Minami N, Katoh M, Sugai K, Goto Y, Tamura T, Yamamoto N, Ohe Y, Kunitoh H, Nokihara H, Yoshida T, Minami H, Saijo N, Ando M, Ozawa S, Saito Y, Sawada J. Hichiya H, et al. Among authors: saito y. Drug Metab Dispos. 2005 May;33(5):630-6. doi: 10.1124/dmd.105.003830. Epub 2005 Feb 16. Drug Metab Dispos. 2005. PMID: 15716363
Functional characterization of three naturally occurring single nucleotide polymorphisms in the CES2 gene encoding carboxylesterase 2 (HCE-2).
Kubo T, Kim SR, Sai K, Saito Y, Nakajima T, Matsumoto K, Saito H, Shirao K, Yamamoto N, Minami H, Ohtsu A, Yoshida T, Saijo N, Ohno Y, Ozawa S, Sawada J. Kubo T, et al. Among authors: saito h, saito y. Drug Metab Dispos. 2005 Oct;33(10):1482-7. doi: 10.1124/dmd.105.005587. Epub 2005 Jul 20. Drug Metab Dispos. 2005. PMID: 16033949
9,402 results