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Molecular mechanisms involved in differentiated thyroid cancer invasion and metastasis.
Vasko VV, Saji M. Vasko VV, et al. Among authors: saji m. Curr Opin Oncol. 2007 Jan;19(1):11-7. doi: 10.1097/CCO.0b013e328011ab86. Curr Opin Oncol. 2007. PMID: 17133106 Review.
AKT activation promotes metastasis in a mouse model of follicular thyroid carcinoma.
Kim CS, Vasko VV, Kato Y, Kruhlak M, Saji M, Cheng SY, Ringel MD. Kim CS, et al. Among authors: saji m. Endocrinology. 2005 Oct;146(10):4456-63. doi: 10.1210/en.2005-0172. Epub 2005 Jul 7. Endocrinology. 2005. PMID: 16002527
AKT in thyroid tumorigenesis and progression.
Shinohara M, Chung YJ, Saji M, Ringel MD. Shinohara M, et al. Among authors: saji m. Endocrinology. 2007 Mar;148(3):942-7. doi: 10.1210/en.2006-0937. Epub 2006 Aug 31. Endocrinology. 2007. PMID: 16946008 Review.
Thyroid follicular adenomas may display features of follicular carcinoma and follicular variant of papillary carcinoma.
Vasko VV, Gaudart J, Allasia C, Savchenko V, Di Cristofaro J, Saji M, Ringel MD, De Micco C. Vasko VV, et al. Among authors: saji m. Eur J Endocrinol. 2004 Dec;151(6):779-86. doi: 10.1530/eje.0.1510779. Eur J Endocrinol. 2004. PMID: 15588246
Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkar1a and Pten in mice.
Pringle DR, Vasko VV, Yu L, Manchanda PK, Lee AA, Zhang X, Kirschner JM, Parlow AF, Saji M, Jarjoura D, Ringel MD, La Perle KM, Kirschner LS. Pringle DR, et al. Among authors: saji m. J Clin Endocrinol Metab. 2014 May;99(5):E804-12. doi: 10.1210/jc.2013-3101. Epub 2014 Feb 10. J Clin Endocrinol Metab. 2014. PMID: 24512487 Free PMC article.
Phase II trial of sorafenib in metastatic thyroid cancer.
Kloos RT, Ringel MD, Knopp MV, Hall NC, King M, Stevens R, Liang J, Wakely PE Jr, Vasko VV, Saji M, Rittenberry J, Wei L, Arbogast D, Collamore M, Wright JJ, Grever M, Shah MH. Kloos RT, et al. Among authors: saji m. J Clin Oncol. 2009 Apr 1;27(10):1675-84. doi: 10.1200/JCO.2008.18.2717. Epub 2009 Mar 2. J Clin Oncol. 2009. PMID: 19255327 Free PMC article. Clinical Trial.
Group I p21-activated kinases regulate thyroid cancer cell migration and are overexpressed and activated in thyroid cancer invasion.
McCarty SK, Saji M, Zhang X, Jarjoura D, Fusco A, Vasko VV, Ringel MD. McCarty SK, et al. Among authors: saji m. Endocr Relat Cancer. 2010 Oct 29;17(4):989-99. doi: 10.1677/ERC-10-0168. Print 2010 Dec. Endocr Relat Cancer. 2010. PMID: 20817787 Free PMC article.
Systemic administration of vascular endothelial growth factor monoclonal antibody reduces the growth of papillary thyroid carcinoma in a nude mouse model.
Bauer AJ, Patel A, Terrell R, Doniparthi K, Saji M, Ringel M, Tuttle RM, Francis GL. Bauer AJ, et al. Among authors: saji m. Ann Clin Lab Sci. 2003 Spring;33(2):192-9. Ann Clin Lab Sci. 2003. PMID: 12817624
Gene expression and functional evidence of epithelial-to-mesenchymal transition in papillary thyroid carcinoma invasion.
Vasko V, Espinosa AV, Scouten W, He H, Auer H, Liyanarachchi S, Larin A, Savchenko V, Francis GL, de la Chapelle A, Saji M, Ringel MD. Vasko V, et al. Among authors: saji m. Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2803-8. doi: 10.1073/pnas.0610733104. Epub 2007 Feb 12. Proc Natl Acad Sci U S A. 2007. PMID: 17296934 Free PMC article.
Human herpes simplex viruses in benign and malignant thyroid tumours.
Jensen K, Patel A, Larin A, Hoperia V, Saji M, Bauer A, Yim K, Hemming V, Vasko V. Jensen K, et al. Among authors: saji m. J Pathol. 2010 Jun;221(2):193-200. doi: 10.1002/path.2701. J Pathol. 2010. PMID: 20455254
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